Publications by authors named "Letitia Jean"

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The malaria parasite egress protease SUB1 is activated through precise, plasmepsin X-mediated cleavage of the SUB1 prodomain.
Chrislaine Withers-Martinez, Roger George, Sarah Maslen, Létitia Jean, Fiona Hackett

Biochim Biophys Acta Gen Subj· September 2024

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The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion.
Viola Introini, Alejandro Marin-Menendez, Guilherme Nettesheim, Yen-Chun Lin, Silvia N Kariuki, Letitia Jean

Sci Rep· May 2022

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The kinetics of islet amyloid polypeptide phase-separated system and hydrogel formation are critically influenced by macromolecular crowding.
Lior Pytowski, David J Vaux, Létitia Jean

Biochem J· August 2021

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Liquid-liquid phase separation of type II diabetes-associated IAPP initiates hydrogelation and aggregation.
Lior Pytowski, Chiu Fan Lee, Alex C Foley, David J Vaux, Létitia Jean

Proc Natl Acad Sci U S A· June 2020

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localization of human acetylcholinesterase-derived species in a β-sheet conformation at the core of senile plaques in Alzheimer's disease.
Létitia Jean, Stephen Brimijoin, David J Vaux

J Biol Chem· April 2019

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Reverse immunodynamics: a new method for identifying targets of protective immunity.
Katrina J Spensley, Paul S Wikramaratna, Bridget S Penman, Andrew Walker, Adrian L Smith, Létitia Jean

Sci Rep· February 2019

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Multiphasic effect of vinyl pyrrolidone polymers on amyloidogenesis, from macromolecular crowding to inhibition.
Richard Berwick, David J Vaux, Létitia Jean

Biochem J· November 2018

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The Physiological and Pathological Implications of the Formation of Hydrogels, with a Specific Focus on Amyloid Polypeptides.
Létitia Jean, Alex C Foley, David J T Vaux

Biomolecules· September 2017

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Dynamics of the formation of a hydrogel by a pathogenic amyloid peptide: islet amyloid polypeptide.
Létitia Jean, Chiu Fan Lee, Peter Hodder, Nick Hawkins, David J Vaux

Sci Rep· August 2016

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The air-water interface determines the outcome of seeding during amyloidogenesis.
Ben J Trigg, Chiu Fan Lee, David J Vaux, Létitia Jean

Biochem J· November 2013

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Combined effects of agitation, macromolecular crowding, and interfaces on amyloidogenesis.
Chiu Fan Lee, Sarah Bird, Michael Shaw, Létitia Jean, David J Vaux

J Biol Chem· November 2012

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Enrichment of amyloidogenesis at an air-water interface.
Létitia Jean, Chiu Fan Lee, David J Vaux

Biophys J· March 2012

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Competing discrete interfacial effects are critical for amyloidogenesis.
Létitia Jean, Chiu Fan Lee, Chongsoo Lee, Michael Shaw, David J Vaux

FASEB J· January 2010

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Elongation dynamics of amyloid fibrils: a rugged energy landscape picture.
Chiu Fan Lee, James Loken, Létitia Jean, David J Vaux

Phys Rev E Stat Nonlin Soft Matter Phys· October 2009

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Structural elements regulating amyloidogenesis: a cholinesterase model system.
Létitia Jean, Chiu Fan Lee, Michael Shaw, David J Vaux

PLoS One· March 2008

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Heterologous amyloid seeding: revisiting the role of acetylcholinesterase in Alzheimer's disease.
Létitia Jean, Benjamin Thomas, Abdessamad Tahiri-Alaoui, Michael Shaw, David J Vaux

PLoS One· July 2007

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Unique insertions within Plasmodium falciparum subtilisin-like protease-1 are crucial for enzyme maturation and activity.
Létitia Jean, Chrislaine Withers-Martinez, Fiona Hackett, Michael J Blackman

Mol Biochem Parasitol· December 2005

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Subtilisin-like proteases of the malaria parasite.
Chrislaine Withers-Martinez, Létitia Jean, Michael J Blackman

Mol Microbiol· July 2004

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Functional characterization of the propeptide of Plasmodium falciparum subtilisin-like protease-1.
Letitia Jean, Fiona Hackett, Stephen R Martin, Michael J Blackman

J Biol Chem· August 2003

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