Publications by authors named "Peter Hodder"

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Creating a more strategic small molecule biophysical hit characterization workflow.
Christopher Fotsch, Debaleena Basu, Ryan Case, Qing Chen, Pratibha C Koneru, Peter Hodder

SLAS Discov· June 2024

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A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Zaizhou Liu, Kaige Chen, Jun Dai, Peng Xu, Wei Sun, Peter Hodder

Cell Res· January 2023

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Hit Discovery Methodology.
Mark Wigglesworth, Peter Hodder

SLAS Discov· February 2021

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Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment.
Leiming Wang, Chiang-Min Cheng, Jun Qin, Mafei Xu, Chung-Yang Kao, Peter Hodder

Sci Adv· May 2020

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Identification of Antimalarial Inhibitors Using Late-Stage Gametocytes in a Phenotypic Live/Dead Assay.
Timothy P Spicer, Donald L Gardiner, Frank J Schoenen, Sudeshna Roy, Patrick R Griffin, Peter Hodder

SLAS Discov· January 2019

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Identification of Novel, Structurally Diverse, Small Molecule Modulators of GPR119.
Ainhoa Nieto, Virneliz Fernández-Vega, Timothy P Spicer, Emmanuel Sturchler, Pramisha Adhikari, Peter Hodder

Assay Drug Dev Technol· July 2018

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Improved Scalability of Neuron-Based Phenotypic Screening Assays for Therapeutic Discovery in Neuropsychiatric Disorders.
Timothy P Spicer, Christopher Hubbs, Thomas Vaissiere, Deanna Collia, Camilo Rojas, Peter Hodder

Mol Neuropsychiatry· February 2018

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An Ultra-High-Throughput Screen for Catalytic Inhibitors of Serine/Threonine Protein Phosphatases Types 1 and 5 (PP1C and PP5C).
Mark Swingle, Claude-Henry Volmar, S Adrian Saldanha, Peter Chase, Christina Eberhart, Peter Hodder

SLAS Discov· January 2017

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Development of an HTS-Compatible Assay for Discovery of Melanoma-Related Microphthalmia Transcription Factor Disruptors Using AlphaScreen Technology.
Jing Wang, Pengfei Fang, Peter Chase, Sagi Tshori, Ehud Razin, Peter Hodder

SLAS Discov· January 2017

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Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition.
Michael R Wood, Meredith J Noetzel, James C Tarr, Alice L Rodriguez, Atin Lamsal, Peter S Hodder

Bioorg Med Chem Lett· September 2016

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Fluorometric High-Throughput Screening Assay for Secreted Phospholipases A2 Using Phospholipid Vesicles.
Heather Ewing, Virneliz Fernández-Vega, Timothy P Spicer, Peter Chase, Steven Brown, Peter Hodder

J Biomol Screen· August 2016

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Electroactive biomimetic collagen-silver nanowire composite scaffolds.
Abeni Wickham, Mikhail Vagin, Hazem Khalaf, Sergio Bertazzo, Peter Hodder

Nanoscale· August 2016

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Dynamics of the formation of a hydrogel by a pathogenic amyloid peptide: islet amyloid polypeptide.
Létitia Jean, Chiu Fan Lee, Peter Hodder, Nick Hawkins, David J Vaux

Sci Rep· August 2016

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Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core.
Michael R Wood, Meredith J Noetzel, Julie L Engers, Katrina A Bollinger, Bruce J Melancon, Peter S Hodder

Bioorg Med Chem Lett· July 2016

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Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation.
Lars Plate, Christina B Cooley, John J Chen, Ryan J Paxman, Ciara M Gallagher, Peter Hodder

Elife· July 2016

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Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1.
Pamela Y Ting, Robert Damoiseaux, Björn Titz, Kenneth A Bradley, Thomas G Graeber, Peter Hodder

PLoS One· February 2016

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Selective Targeting of Extracellular Insulin-Degrading Enzyme by Quasi-Irreversible Thiol-Modifying Inhibitors.
Samer O Abdul-Hay, Thomas D Bannister, Hui Wang, Michael D Cameron, Thomas R Caulfield, Peter Hodder

ACS Chem Biol· December 2015

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Endogenous and Synthetic ABHD5 Ligands Regulate ABHD5-Perilipin Interactions and Lipolysis in Fat and Muscle.
Matthew A Sanders, Franck Madoux, Ljiljana Mladenovic, Huamei Zhang, Xiangqun Ye, Peter Hodder

Cell Metab· November 2015

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Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4).
Emery Smith, Peter Chase, Colleen M Niswender, Thomas J Utley, Douglas J Sheffler, Peter Hodder

J Biomol Screen· August 2015

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Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.
Stuart L Schreiber, Joanne D Kotz, Min Li, Jeffrey Aubé, Christopher P Austin, Peter S Hodder

Cell· June 2015

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Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival.
Jae Won Chang, Andrea M Zuhl, Anna E Speers, Sherry Niessen, Steven J Brown, Peter S Hodder

ACS Chem Biol· April 2015

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Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.
Nan Zhao, Crystal M Darby, Jennifer Small, Daniel A Bachovchin, Xiuju Jiang, Peter S Hodder

ACS Chem Biol· February 2015

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Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylases.
Yunfei Wang, Ryan L Stowe, Christie E Pinello, Guimei Tian, Franck Madoux, Peter Hodder

Chem Biol· February 2015

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