Publications by authors named "Lewis Patrick"

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GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis.
Erin C Bogacki, Gustavo Morrone Parfitt, Adriana Cunha, George Longmore, Selina Wray, Patrick A Lewis

Sci Adv· December 2025

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Passive environmental DNA (eDNA) sampling is effective for monitoring vessel biofouling in the Southern Ocean.
Frances Perry, Justine D Shaw, Phillip Cassey, Ashley Coutts, Patrick N Lewis

Sci Total Environ· December 2025

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The scimitar-cat Homotherium from the submerged continental shelf of the Gulf Coast of Texas.
John A Moretti, Deanna Flores, Christopher J Bell, Will Godwin, Adam Hartstone-Rose, Patrick J Lewis

Anat Rec (Hoboken)· November 2025

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Glutamic Acid at Position 168 Is a Constitutive Activator of Tank Binding Kinase 1 Catalytic Function.
Noopur Bhore, Anubhuti Sarkar, Zhi Yao, Susanne Herbst, Patrick A Lewis

Neuromolecular Med· November 2025

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New Frontiers in Animal Prion Diseases.
Hasina Abdul, Timm Konold, John Spiropoulos, Patrick A Lewis

Annu Rev Anim Biosci· November 2025

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Prevalence and Clinical Characteristics of the LRRK2 p.L1795F Variant in Central Europeans with Early-Onset and Familial Parkinson's Disease.
Miriam Ostrozovicova, Gertrud Tamas, Agsha Atputhavadivel, Petr Dusek, Milan Grofik, Patrick Lewis

Mov Disord Clin Pract· August 2025

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Variants in the proteasome regulator PSMF1 cause a phenotypic spectrum from early-onset Parkinson's disease to perinatal lethality and disrupt mitochondrial function.
Francesca Magrinelli, Christelle Tesson, Plamena R Angelova, Jose A Rodriguez, Annarita Scardamaglia, Patrick A Lewis

medRxiv· July 2025

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Loss-of-function coding variants in the Ras of complex proteins/GTPase domain of leucine rich repeat kinase 2.
Sarah Butterfield, Susanne Herbst, Patrick Alfryn Lewis

Protein Sci· July 2025

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Evidence suggesting that microglia make amyloid from neuronally expressed APP: a hypothesis.
John Hardy, Patrick Lewis

Mol Neurodegener· May 2025

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Elimination of intra-hepatocytic malaria parasites is driven by non-canonical autophagy but not nitric oxide production.
Antonino Schepis, Jonas E Mertens, Patrick Lewis, Hardik Patel, Noah Stegman

iScience· April 2025

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Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors.
Deniz Kent, Soon Seng Ng, Adam M Syanda, Payam Khoshkenar, Riccardo Ronzoni, Patrick A Lewis

Hepatology· March 2025

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Robert Carswell and his depiction of sclerotic plaques.
Patrick A Lewis

Mult Scler Relat Disord· November 2024

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The specialized inner ear labyrinth of worm-lizards (Amphisbaenia: Squamata).
Geneva E Clark, Alessandro Palci, Rebecca J Laver, Cristian Hernandez-Morales, Christian A Perez-Martinez, Patrick J Lewis

PLoS One· November 2024

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Microglia contribute to the production of the amyloidogenic ABri peptide in familial British dementia.
Charles Arber, Jackie M Casey, Samuel Crawford, Naiomi Rambarack, Umran Yaman, Patrick A Lewis

Acta Neuropathol· November 2024

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Effect of volatile anaesthetic agents on intracranial pressure, cerebrovascular flow and autoregulation: a protocol for a systematic review and meta-analysis.
Ben Taylor, Jack Ellis, Sam Ponty, Lewis Patrick, Timothy E Scott

BMJ Open· September 2024

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Transcriptomics and weighted protein network analyses of the LRRK2 protein interactome reveal distinct molecular signatures for sporadic and LRRK2 Parkinson's Disease.
Yibo Zhao, Matthew Bracher-Smith, Yuelin Li, Kirsten Harvey, Valentina Escott-Price, Patrick A Lewis

NPJ Parkinsons Dis· August 2024

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LRRK2 kinase activity is necessary for development and regeneration in Nematostella vectensis.
Grace Holmes, Sophie R Ferguson, Patrick Alfryn Lewis, Karen Echeverri

Neural Dev· August 2024

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p.L1795F LRRK2 variant is a common cause of Parkinson's disease in Central Europe.
Miriam Ostrozovicova, Gertrud Tamas, Petr Dušek, Milan Grofik, Vladimir Han, Patrick Lewis

Res Sq· May 2024

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Common genetic risk for Parkinson's disease and dysfunction of the endo-lysosomal system.
Noopur Bhore, Erin C Bogacki, Benjamin O'Callaghan, Helene Plun-Favreau, Patrick A Lewis

Philos Trans R Soc Lond B Biol Sci· April 2024

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Cranial anatomy of the "round-headed" Amphisbaenian Zygaspis quadrifrons (Squamata, Amphisbaenia) based on high-resolution x-ray computed tomography.
Christopher J Bell, Cristhian Cadena, Antonio Meza, Lauren Rudie, Patrick J Lewis

Anat Rec (Hoboken)· March 2024

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Variation in the cranial osteology of the amphisbaenian genus Zygaspis based on high-resolution x-ray computed tomography.
Antonio Meza, Christopher J Bell, Juan D Daza, Monte L Thies, Patrick J Lewis

Anat Rec (Hoboken)· March 2024

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Artificial intelligence for neurodegenerative experimental models.
Sarah J Marzi, Brian M Schilder, Alexi Nott, Carlo Sala Frigerio, Sandrine Willaime-Morawek, Patrick A Lewis

Alzheimers Dement· December 2023

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Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2.
Iqra Nazish, Adamantios Mamais, Anna Mallach, Conceicao Bettencourt, Alice Kaganovich, Patrick A Lewis

Cells· December 2023

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LRRK2 kinase activity is necessary for development and regeneration in Nematostella vectensis.
Grace Holmes, Sophie R Ferguson, Patrick Alfryn Lewis, Karen Echeverri

Res Sq· November 2023

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Differential LRRK2 signalling and gene expression in WT-LRRK2 and G2019S-LRRK2 mouse microglia treated with zymosan and MLi2.
Iqra Nazish, Adamantios Mamais, Anna Mallach, Conceicao Bettencourt, Alice Kaganovich, Patrick A Lewis

bioRxiv· September 2023

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