Publications by authors named "Lifan Zeng"

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Use of a Near Infrared Probe to Assess Intracellular Hydrogen Sulfide Production.
Fikir M Mesfin, Lifan Zeng, Krishna Manohar, Chelsea E Hunter, W Christopher Shelley

J Surg Res· December 2025

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phenazines dictate site-specific competitive interactions with .
Katlyn Todd, Olivia Schneider, Joshua M Lawrence, Josefina L Aronoff, Bartosz Witek, Lifan Zeng

bioRxiv· August 2025

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Critical role of Oas1g and STAT1 pathways in neuroinflammation: insights for Alzheimer's disease therapeutics.
Zhixin Xie, Linxi Li, Weizhong Hou, Zhongxi Fan, Lifan Zeng

J Transl Med· February 2025

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Warfarin analogs target disulfide bond-forming enzymes and suggest a residue important for quinone and coumarin binding.
Dariana Chavez, Gwendolyn Nita Amarquaye, Adrian Mejia-Santana, Dyotima, Kayley Ryan, Lifan Zeng

J Biol Chem· June 2024

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Chondroitin sulfate supplementation improves clinical outcomes in a murine model of necrotizing enterocolitis.
Krishna Manohar, Brian D Hosfield, Fikir M Mesfin, Cameron Colgate, William Christopher Shelley, Lifan Zeng

Physiol Rep· September 2023

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Translation Rescue by Targeting Ppp1r15a through Its Upstream Open Reading Frame in Sepsis-Induced Acute Kidney Injury in a Murine Model.
Ashley Kidwell, Shiv Pratap Singh Yadav, Bernhard Maier, Amy Zollman, Kevin Ni, Lifan Zeng

J Am Soc Nephrol· February 2023

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Fast and high-throughput LC-MS characterization, and peptide mapping of engineered AAV capsids using LC-MS/MS.
Anh K Lam, Junping Zhang, Dylan Frabutt, Patrick L Mulcrone, Lei Li, Lifan Zeng

Mol Ther Methods Clin Dev· December 2022

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Study on dynamic changes of microbial community and lignocellulose transformation mechanism during green waste composting.
Yushan Zhang, Mengting Chen, Jingyi Guo, Ning Liu, Weiyi Yi, Lifan Zeng

Eng Life Sci· May 2022

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ALDH1 Bio-activates Nifuroxazide to Eradicate ALDH Melanoma-Initiating Cells.
Sana Sarvi, Richard Crispin, Yuting Lu, Lifan Zeng, Thomas D Hurley

Cell Chem Biol· December 2018

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Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases.
Lakshmi Prabhu, Lan Chen, Han Wei, Özlem Demir, Ahmad Safa, Lifan Zeng

Mol Biosyst· November 2017

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Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.
Lakshmi Prabhu, Han Wei, Lan Chen, Özlem Demir, George Sandusky, Lifan Zeng

Oncotarget· June 2017

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SHP2 phosphatase as a novel therapeutic target for melanoma treatment.
Ruo-Yu Zhang, Zhi-Hong Yu, Lifan Zeng, Sheng Zhang, Yunpeng Bai

Oncotarget· November 2016

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Novel Anticancer Agents Based on Targeting the Trimer Interface of the PRL Phosphatase.
Yunpeng Bai, Zhi-Hong Yu, Sijiu Liu, Lujuan Zhang, Ruo-Yu Zhang, Li-Fan Zeng

Cancer Res· August 2016

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Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus.
Jianxun Wang, Masayuki Mizui, Li-Fan Zeng, Roderick Bronson, Michele Finnell

J Clin Invest· June 2016

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Abnormal enhancer methylation promotes rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and joint inflammation.
Keisuke Maeshima, Stephanie M Stanford, Deepa Hammaker, Cristiano Sacchetti, Li-Fan Zeng

JCI Insight· May 2016

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Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis.
Severa Bunda, Kelly Burrell, Pardeep Heir, Lifan Zeng, Amir Alamsahebpour

Nat Commun· November 2015

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Shp2 and Pten have antagonistic roles in myeloproliferation but cooperate to promote erythropoiesis in mammals.
Helen He Zhu, Xiaolin Luo, Kaiqing Zhang, Jian Cui, Huifang Zhao, Lifan Zeng

Proc Natl Acad Sci U S A· October 2015

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Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.
Rongjun He, Zhi-Hong Yu, Ruo-Yu Zhang, Li Wu, Andrea M Gunawan, Li-Fan Zeng

ACS Med Chem Lett· July 2015

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Therapeutic potential of targeting the oncogenic SHP2 phosphatase.
Li-Fan Zeng, Ruo-Yu Zhang, Zhi-Hong Yu, Sijiu Li, Li Wu

J Med Chem· August 2014

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Oncogenic KIT-induced aggressive systemic mastocytosis requires SHP2/PTPN11 phosphatase for disease progression in mice.
Namit Sharma, Stephanie Everingham, Li-Fan Zeng, Zhong-Yin Zhang, Reuben Kapur

Oncotarget· August 2014

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Hydroxyindole carboxylic acid-based inhibitors for receptor-type protein tyrosine protein phosphatase beta.
Li-Fan Zeng, Ruo-Yu Zhang, Yunpeng Bai, Li Wu, Andrea M Gunawan

Antioxid Redox Signal· May 2014

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Targeting SHP2 for EGFR inhibitor resistant non-small cell lung carcinoma.
Jie Xu, Li-Fan Zeng, Weihua Shen, John J Turchi, Zhong-Yin Zhang

Biochem Biophys Res Commun· October 2013

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A facile hydroxyindole carboxylic acid based focused library approach for potent and selective inhibitors of Mycobacterium protein tyrosine phosphatase B.
Li-Fan Zeng, Jie Xu, Yantao He, Rongjun He, Li Wu

ChemMedChem· June 2013

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Organocatalytic multicomponent reaction for the acquisition of a selective inhibitor of mPTPB, a virulence factor of tuberculosis.
Rongjun He, Li-Fan Zeng, Yantao He, Li Wu, Andrea Michelle Gunawan

Chem Commun (Camb)· March 2013

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Repositioning HIV-1 integrase inhibitors for cancer therapeutics: 1,6-naphthyridine-7-carboxamide as a promising scaffold with drug-like properties.
Li-Fan Zeng, Yong Wang, Roza Kazemi, Shili Xu, Zhong-Liang Xu

J Med Chem· November 2012

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