Publications by authors named "Lilly Chai"

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AAV gene therapy for GBA1-related diseases.
Swathi Ayloo, Jae Cheon Ryu, Shih-Ching Chou, Lydia Blatnik, Erik Wischhof, Lilly Chai

Mol Ther· December 2025

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Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors.
John L Buchanan, John R Newcomb, David P Carney, Stuart C Chaffee, Lilly Chai

Bioorg Med Chem Lett· April 2011

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The chemosensitizing activity of inhibitors of glucosylceramide synthase is mediated primarily through modulation of P-gp function.
Lilly Chai, Rajashree P McLaren, Ann Byrne, Wei-Lien Chuang, Yinyin Huang

Int J Oncol· March 2011

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Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence.
Ann Byrne, Rajashree P McLaren, Paul Mason, Lilly Chai, Michael R Dufault

Exp Cell Res· January 2010

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Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity.
Matthew W Martin, John Newcomb, Joseph J Nunes, Christina Boucher, Lilly Chai

J Med Chem· March 2008

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Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.
Erin F DiMauro, John Newcomb, Joseph J Nunes, Jean E Bemis, Christina Boucher, Lilly Chai

J Med Chem· March 2008

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Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.
Erin F DiMauro, John Newcomb, Joseph J Nunes, Jean E Bemis, Christina Boucher, Lilly Chai

J Med Chem· September 2006

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Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity.
Matthew W Martin, John Newcomb, Joseph J Nunes, David C McGowan, David M Armistead, Lilly Chai

J Med Chem· August 2006

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