Publications by authors named "Stuart C Chaffee"

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Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors.
John L Buchanan, John R Newcomb, David P Carney, Stuart C Chaffee, Lilly Chai

Bioorg Med Chem Lett· April 2011

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Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.
Erin F DiMauro, John Newcomb, Joseph J Nunes, Jean E Bemis, Christina Boucher, Stuart C Chaffee

J Med Chem· March 2008

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Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors.
Brian L Hodous, Stephanie D Geuns-Meyer, Paul E Hughes, Brian K Albrecht, Steve Bellon, Stuart C Chaffee

Bioorg Med Chem Lett· May 2007

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Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor.
Brian L Hodous, Stephanie D Geuns-Meyer, Paul E Hughes, Brian K Albrecht, Steve Bellon, Stuart C Chaffee

J Med Chem· February 2007

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Alkynylpyrimidine amide derivatives as potent, selective, and orally active inhibitors of Tie-2 kinase.
Victor J Cee, Brian K Albrecht, Stephanie Geuns-Meyer, Paul Hughes, Steve Bellon, Stuart C Chaffee

J Med Chem· February 2007

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