Publications by authors named "Lily Jan"

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Atypical developmental remodeling of dopamine neurons involves AKT-GSK3β signaling and glia activity.
Xiaofan Zhang, Wei Chen, Yayu Wang, Xun Tu, Xiangyu Zhang, Lily Yeh Jan, Yuh Nung Jan

bioRxiv· November 2025

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A cell-based scrambling assay reveals the phospholipid headgroup preference of TMEM16F on the plasma membrane.
Chin Fen Teo, Sami T Tuomivaara, Niek van Hilten, David Crottès, Yuh Nung Jan, Lily Y Jan

Proc Natl Acad Sci U S A· November 2025

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Identification of the peptide Vulnusin, a wound signal that mediates mechanical-injury-induced nociception in Drosophila.
Yanmeng Guo, Tun Li, Sami T Tuomivaara, Chin Fen Teo, Shengjie Feng, Lily Yeh Jan, Yuh Nung Jan

Neuron· October 2025

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A cell-based scrambling assay reveals phospholipid headgroup preference of TMEM16F on the plasma membrane.
Chin Fen Teo, Sami T Tuomivaara, Niek van Hilten, David Crottès, Yuh Nung Jan, Lily Y Jan

bioRxiv· June 2025

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Wide-ranging cellular functions of ion channels and lipid scramblases in the structurally related TMC, TMEM16 and TMEM63 families.
Lily Yeh Jan, Yuh Nung Jan

Nat Struct Mol Biol· February 2025

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Voltage sensors.
Lily Jan

Mol Pharmacol· February 2025

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SLAPSHOT reveals rapid dynamics of extracellularly exposed proteome in response to calcium-activated plasma membrane phospholipid scrambling.
Sami T Tuomivaara, Chin Fen Teo, Yuh Nung Jan, Arun P Wiita, Lily Y Jan

Commun Biol· August 2024

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TMEM16F exacerbates tau pathology and mediates phosphatidylserine exposure in phospho-tau-burdened neurons.
Mario V Zubia, Adeline J H Yong, Kristen M Holtz, Eric J Huang, Yuh Nung Jan, Lily Y Jan

Proc Natl Acad Sci U S A· July 2024

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Nonlinear compliance of NompC gating spring and its implication in mechanotransduction.
Yukun Wang, Peng Jin, Avinash Kumar, Lily Jan, Yifan Cheng, Yuh-Nung Jan

bioRxiv· June 2024

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A personal perspective of the voltage-gated potassium channel studies.
Lily Yeh Jan, Yuh Nung Jan

Nat Struct Mol Biol· April 2024

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Drosophila TMEM63 and mouse TMEM63A are lysosomal mechanosensory ion channels.
Kai Li, Yanmeng Guo, Yayu Wang, Ruijun Zhu, Wei Chen, Lily Yeh Jan, Yuh Nung Jan

Nat Cell Biol· March 2024

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Rare variants in ANO1, encoding a calcium-activated chloride channel, predispose to moyamoya disease.
Amélie Pinard, Wenlei Ye, Stuart M Fraser, Jill A Rosenfeld, Pavel Pichurin, Lily Yeh Jan

Brain· September 2023

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Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase.
Shengjie Feng, Cristina Puchades, Juyeon Ko, Hao Wu, Yifei Chen, Yuh Nung Jan, Lily Yeh Jan

Nat Commun· August 2023

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SLAPSHOT reveals rapid dynamics of extracellularly exposed proteome in response to calcium-activated plasma membrane phospholipid scrambling.
Sami T Tuomivaara, Chin Fen Teo, Yuh Nung Jan, Lily Y Jan, Arun P Wiita

bioRxiv· March 2023

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The GARP complex prevents sterol accumulation at the trans-Golgi network during dendrite remodeling.
Caitlin E O'Brien, Susan H Younger, Lily Yeh Jan, Yuh Nung Jan

J Cell Biol· January 2023

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A photo-switchable assay system for dendrite degeneration and repair in .
Han-Hsuan Liu, Chien-Hsiang Hsu, Lily Y Jan, Yuh-Nung Jan

Proc Natl Acad Sci U S A· August 2022

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Activation and closed-state inactivation mechanisms of the human voltage-gated K4 channel complexes.
Wenlei Ye, Hongtu Zhao, Yaxin Dai, Yingdi Wang, Yu-Hua Lo, Lily Yeh Jan

Mol Cell· July 2022

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K1.1 preserves the neural stem cell pool and facilitates neuron maturation during adult hippocampal neurogenesis.
Yuan-Hung Lin King, Chao Chen, John V Lin King, Jeffrey Simms, Edward Glasscock, Yuh-Nung Jan, Lily Y Jan

Proc Natl Acad Sci U S A· May 2022

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Steroid hormone signaling activates thermal nociception during peripheral nervous system development.
Jacob S Jaszczak, Laura DeVault, Lily Yeh Jan, Yuh Nung Jan

Elife· March 2022

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Identification of a conserved drug binding pocket in TMEM16 proteins.
Yifan Cheng, Shengjie Feng, Cristina Puchades, Juyeon Ko, Eric Figueroa, Yuh Nung Jan, Lily Jan

Res Sq· February 2022

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Structure, function and pharmacology of human itch GPCRs.
Can Cao, Hye Jin Kang, Isha Singh, He Chen, Chengwei Zhang, Lily Y Jan

Nature· December 2021

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TMEM16C is involved in thermoregulation and protects rodent pups from febrile seizures.
Tongfei A Wang, Chao Chen, Fen Huang, Shengjie Feng, Jason Tien, Yuh Nung Jan, Lily Yeh Jan

Proc Natl Acad Sci U S A· May 2021

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Kv1.1 channels regulate early postnatal neurogenesis in mouse hippocampus via the TrkB signaling pathway.
Shu-Min Chou, Ke-Xin Li, Ming-Yueh Huang, Chao Chen, Yuan-Hung Lin King, Yuh Nung Jan, Lily Yeh Jan

Elife· May 2021

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Multi-scale spatial heterogeneity enhances particle clearance in airway ciliary arrays.
Guillermina R Ramirez-San Juan, Arnold J T M Mathijssen, Mu He, Lily Jan, Wallace Marshall

Nat Phys· September 2020

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TMEM16K is an interorganelle regulator of endosomal sorting.
Maja Petkovic, Juan Oses-Prieto, Alma Burlingame, Lily Yeh Jan, Yuh Nung Jan

Nat Commun· July 2020

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