Publications by authors named "Lin Guey"

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In vivo chimeric antigen receptor (CAR)-T cell therapy.
Adrian Bot, Andrew Scharenberg, Kevin Friedman, Lin Guey, Robert Hofmeister

Nat Rev Drug Discov· September 2025

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Characterizing the mechanism of action for mRNA therapeutics for the treatment of propionic acidemia, methylmalonic acidemia, and phenylketonuria.
Rena Baek, Kimberly Coughlan, Lei Jiang, Min Liang, Lei Ci, Lin Guey

Nat Commun· May 2024

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Dual mRNA therapy restores metabolic function in long-term studies in mice with propionic acidemia.
Lei Jiang, Ji-Sun Park, Ling Yin, Rodrigo Laureano, Eric Jacquinet, Lin T Guey

Nat Commun· October 2020

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Disease pharmacokinetic-pharmacodynamic modelling in acute intermittent porphyria to support the development of mRNA-based therapies.
Zinnia P Parra-Guillen, Antonio Fontanellas, Lei Jiang, Daniel Jericó, Paolo Martini, Lin T Guey

Br J Pharmacol· July 2020

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A New Era for Rare Genetic Diseases: Messenger RNA Therapy.
Paolo G V Martini, Lin T Guey

Hum Gene Ther· October 2019

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mRNA Therapy Improves Metabolic and Behavioral Abnormalities in a Murine Model of Citrin Deficiency.
Jingsong Cao, Ding An, Mikel Galduroz, Jenny Zhuo, Shi Liang, Lin Guey

Mol Ther· July 2019

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Long-term efficacy and safety of mRNA therapy in two murine models of methylmalonic acidemia.
Ding An, Andrea Frassetto, Eric Jacquinet, Marianne Eybye, Joseph Milano, Lin T Guey

EBioMedicine· July 2019

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Systemic mRNA Therapy for the Treatment of Fabry Disease: Preclinical Studies in Wild-Type Mice, Fabry Mouse Model, and Wild-Type Non-human Primates.
Xuling Zhu, Ling Yin, Matt Theisen, Jenny Zhuo, Summar Siddiqui, Lin T Guey

Am J Hum Genet· April 2019

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Systematic literature review and meta-analysis on the epidemiology of methylmalonic acidemia (MMA) with a focus on MMA caused by methylmalonyl-CoA mutase (mut) deficiency.
Tímea Almási, Lin T Guey, Christine Lukacs, Kata Csetneki, Zoltán Vokó

Orphanet J Rare Dis· April 2019

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Systematic literature review and meta-analysis on the epidemiology of propionic acidemia.
Tímea Almási, Lin T Guey, Christine Lukacs, Kata Csetneki, Zoltán Vokó

Orphanet J Rare Dis· February 2019

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Systemic messenger RNA as an etiological treatment for acute intermittent porphyria.
Lei Jiang, Pedro Berraondo, Daniel Jericó, Lin T Guey, Ana Sampedro

Nat Med· December 2018

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Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia.
Ding An, Jessica L Schneller, Andrea Frassetto, Shi Liang, Xuling Zhu, Lin T Guey

Cell Rep· August 2018

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Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia.
Ding An, Jessica L Schneller, Andrea Frassetto, Shi Liang, Xuling Zhu, Lin T Guey

Cell Rep· December 2017

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Speed of processing training results in lower risk of dementia.
Jerri D Edwards, Huiping Xu, Daniel O Clark, Lin T Guey, Lesley A Ross

Alzheimers Dement (N Y)· November 2017

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Collagen VII Half-Life at the Dermal-Epidermal Junction Zone: Implications for Mechanisms and Therapy of Genodermatoses.
Tobias Kühl, Markus Mezger, Ingrid Hausser, Lin T Guey, Rupert Handgretinger

J Invest Dermatol· June 2016

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Intravenously Administered Recombinant Human Type VII Collagen Derived from Chinese Hamster Ovary Cells Reverses the Disease Phenotype in Recessive Dystrophic Epidermolysis Bullosa Mice.
Yingping Hou, Lin T Guey, Timothy Wu, Robert Gao, Jon Cogan

J Invest Dermatol· December 2015

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Genetic variation in the TP53 pathway and bladder cancer risk. a comprehensive analysis.
Silvia Pineda, Roger L Milne, M Luz Calle, Nathaniel Rothman, Evangelina López de Maturana, Lin T Guey

PLoS One· January 2015

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Impact of pre-stage II hemodynamics and pulmonary artery anatomy on 12-month outcomes in the Pediatric Heart Network Single Ventricle Reconstruction trial.
Ranjit Aiyagari, John F Rhodes, Peter Shrader, Wolfgang A Radtke, Varsha M Bandisode, Lin T Guey

J Thorac Cardiovasc Surg· October 2014

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RNAi screening in primary human hepatocytes of genes implicated in genome-wide association studies for roles in type 2 diabetes identifies roles for CAMK1D and CDKAL1, among others, in hepatic glucose regulation.
Steven Haney, Juan Zhao, Shiwani Tiwari, Kurt Eng, Lin T Guey

PLoS One· February 2014

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Relationship of demographic and health factors to cognition in older adults in the ACTIVE study.
Daniel F Rexroth, Sharon L Tennstedt, Richard N Jones, Lin T Guey, George W Rebok

J Aging Health· December 2013

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Multicenter study comparing shunt type in the norwood procedure for single-ventricle lesions: three-dimensional echocardiographic analysis.
Gerald R Marx, Girish Shirali, Jami C Levine, Lin T Guey, James F Cnota

Circ Cardiovasc Imaging· November 2013

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Echocardiographic methods, quality review, and measurement accuracy in a randomized multicenter clinical trial of Marfan syndrome.
Elif Seda Selamet Tierney, Jami C Levine, Shan Chen, Timothy J Bradley, Gail D Pearson, Lin T Guey

J Am Soc Echocardiogr· June 2013

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Characteristics of children and young adults with Marfan syndrome and aortic root dilation in a randomized trial comparing atenolol and losartan therapy.
Ronald V Lacro, Lin T Guey, Harry C Dietz, Gail D Pearson, Anji T Yetman

Am Heart J· May 2013

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Does initial shunt type for the Norwood procedure affect echocardiographic measures of cardiac size and function during infancy?: the Single Vventricle Reconstruction trial.
Peter C Frommelt, Lin T Guey, L LuAnn Minich, Majeed Bhat, Tim J Bradley

Circulation· May 2012

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