Publications by authors named "Line Seguy"

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Peptide-grafted nanogels for sustained endothelin and bradykinin blockade in osteoarthritis.
Seng Manivong, Araceli Garcia-Ac, Louiza Mahrouche, Fabiana Guerra, Line Séguy

Int J Pharm· October 2025

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Growth differentiation factor 5 improves meniscal healing in a pilot study on rats.
David Mazy, Nathaniel Léveillé, Line Séguy, Irene Londono, Florina Moldovan

J Exp Orthop· April 2025

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Evidence from a mouse model supports repurposing an anti-asthmatic drug, bambuterol, against Alzheimer's disease by administration through an intranasal route.
Anne-Claire Groo, Thomas Curel, Aurélie Malzert-Fréon, Line Séguy, Ophélie Bento

Commun Biol· February 2025

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Bioinspired Bottlebrush Polymers Effectively Alleviate Frictional Damage Both In Vitro and In Vivo.
Duy Anh Pham, Chang-Sheng Wang, Line Séguy, Hu Zhang, Sabrina Benbabaali

Adv Mater· June 2024

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In vitro evaluation of NA1-115-7-loaded nanoemulsions, an MCL-1-specific inhibitor of natural origin, intended to treat B-cell lymphoproliferative disorders after oral administration.
Line Séguy, Florian Daressy, Sophia Lahlil, Sophie Corvaisier, Vincent Dumontet

Int J Pharm· January 2023

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NA1-115-7, from Zygogynum pancheri, is a new selective MCL-1 inhibitor inducing the apoptosis of hematological cancer cells but non-toxic to normal blood cells or cardiomyocytes.
Florian Daressy, Line Séguy, Loëtitia Favre, Sophie Corvaisier, Cécile Apel

Biomed Pharmacother· October 2022

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How nano-engineered delivery systems can help marketed and repurposed drugs in Alzheimer's disease treatment?
Line Séguy, Anne-Claire Groo, Aurélie Malzert-Fréon

Drug Discov Today· June 2022

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Active Targeted Nanoemulsions for Repurposing of Tegaserod in Alzheimer's Disease Treatment.
Line Séguy, Léna Guyon, Manon Maurel, Pascal Verdié, Audrey Davis

Pharmaceutics· October 2021

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Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL-1.
Florian Daressy, Florian Malard, Line Seguy, Vincent Guérineau, Cécile Apel

ChemMedChem· June 2021

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Design of Non-Haemolytic Nanoemulsions for Intravenous Administration of Hydrophobic APIs.
Line Séguy, Anne-Claire Groo, Didier Goux, Didier Hennequin, Aurélie Malzert-Fréon

Pharmaceutics· November 2020

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8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi.
Cyril Fersing, Clotilde Boudot, Caroline Castera-Ducros, Emilie Pinault, Sébastien Hutter, Line Seguy

Eur J Med Chem· September 2020

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