Publications by authors named "Lingfeng Fu"

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Frizzled-1 amplification promotes fibrosis in the gastric tumor microenvironment through the activation of fibroblasts via the SLIT2/ROBO1 axis.
Yilin Tong, Takashi Semba, Akiho Nishimura, Atsuko Yonemura, Masaya Yamazaki, Lingfeng Fu

Gastric Cancer· January 2026

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Editorial: Interaction of cell subtypes in tumor microenvironment, and implications for immunotherapy.
Hong Jiang, Lingfeng Fu, Takatsugu Ishimoto, Tao Zhang, Jun Zhang

Front Immunol· April 2025

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Influence of the gut microbiota on immune cell interactions and cancer treatment.
Chunxiao Liu, Lingfeng Fu, Yuxin Wang, Weijun Yang

J Transl Med· October 2024

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RAC1-mediated integrin alpha-6 expression in E-cadherin-deficient gastric cancer cells promotes interactions with the stroma and peritoneal dissemination.
Jun Zhang, Lingfeng Fu, Huaitao Wang, Atsuko Yonemura, Takashi Semba

Cancer Lett· June 2024

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Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment.
Atsuko Yonemura, Takashi Semba, Jun Zhang, Yibo Fan, Noriko Yasuda-Yoshihara, Lingfeng Fu, Fumimasa Kitamura

Cell Rep· January 2024

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Downregulation of 15-PGDH enhances MASH-HCC development via fatty acid-induced T-cell exhaustion.
Xichen Hu, Tadahito Yasuda, Noriko Yasuda-Yosihara, Atsuko Yonemura, Terumasa Umemoto, Lingfeng Fu, Takaichi Fukuda

JHEP Rep· December 2023

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Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer.
Fumimasa Kitamura, Takashi Semba, Noriko Yasuda-Yoshihara, Kosuke Yamada, Akiho Nishimura, Lingfeng Fu

JCI Insight· October 2023

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A novel tdTomato transgenic mouse model to visualize FAP-positive cancer-associated fibroblasts.
Feng Wei, Tomoyuki Uchihara, Atsuko Yonemura, Noriko Yasuda-Yoshihara, Tadahito Yasuda, Masahiro Fukuda, Fumimasa Kitamura, Lingfeng Fu

FEBS J· May 2023

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IL-1β derived from mixed-polarized macrophages activates fibroblasts and synergistically forms a cancer-promoting microenvironment.
Jun Zhang, Lingfeng Fu, Noriko Yasuda-Yoshihara, Atsuko Yonemura, Feng Wei, Fumimasa Kitamura

Gastric Cancer· March 2023

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Stromal Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti-PD-1 Immunotherapy in Fibrotic Tumors.
Takahiko Akiyama, Tadahito Yasuda, Tomoyuki Uchihara, Noriko Yasuda-Yoshihara, Benjy J Y Tan, Lingfeng Fu, Fumimasa Kitamura, Yorifumi Satou

Cancer Res· March 2023

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Tumor microenvironmental 15-PGDH depletion promotes fibrotic tumor formation and angiogenesis in pancreatic cancer.
Luke Bu, Atsuko Yonemura, Noriko Yasuda-Yoshihara, Tomoyuki Uchihara, Galym Ismagulov, Fumimasa Kitamura, Lingfeng Fu, Toshifumi Mukunoki

Cancer Sci· October 2022

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Intracellular MUC20 variant 2 maintains mitochondrial calcium homeostasis and enhances drug resistance in gastric cancer.
Lingfeng Fu, Atsuko Yonemura, Noriko Yasuda-Yoshihara, Terumasa Umemoto, Jun Zhang, Fumimasa Kitamura

Gastric Cancer· May 2022

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A positive feedback loop between gastric cancer cells and tumor-associated macrophage induces malignancy progression.
Haiyan Piao, Lingfeng Fu, Yuxin Wang, Yang Liu, Yue Wang

J Exp Clin Cancer Res· May 2022

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The Gut Microbiota in Inflammatory Bowel Disease.
Peng Qiu, Takatsugu Ishimoto, Lingfeng Fu, Jun Zhang, Zhenyong Zhang

Front Cell Infect Microbiol· April 2022

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Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination.
Tadahito Yasuda, Mayu Koiwa, Atsuko Yonemura, Keisuke Miyake, Ryusho Kariya, Lingfeng Fu, Yoshifumi Baba

Cell Rep· February 2021

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Gastric Cancer Stem Cells: Current Insights into the Immune Microenvironment and Therapeutic Targets.
Lingfeng Fu, Luke Bu, Tadahito Yasuda, Mayu Koiwa, Takahiko Akiyama

Biomedicines· January 2020

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Impact of loss-of-function mutations at the RNF43 locus on colorectal cancer development and progression.
Tsugio Eto, Keisuke Miyake, Katsuhiko Nosho, Masaki Ohmuraya, Yu Imamura, Lingfeng Fu, Yoshifumi Baba, Toru Furukawa

J Pathol· August 2018

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