Publications by authors named "Luke Bu"

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Downregulation of 15-PGDH enhances MASH-HCC development via fatty acid-induced T-cell exhaustion.
Xichen Hu, Tadahito Yasuda, Noriko Yasuda-Yosihara, Atsuko Yonemura, Terumasa Umemoto, Luke Bu

JHEP Rep· December 2023

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Prophylactic Vaccination and Intratumoral Boost with HER2-Expressing Oncolytic Herpes Simplex Virus Induces Robust and Persistent Immune Response against HER2-Positive Tumor Cells.
Zahid Delwar, Olga Tatsiy, Dmitry V Chouljenko, I-Fang Lee, Guoyu Liu, Luke Bu

Vaccines (Basel)· December 2023

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Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer.
Fumimasa Kitamura, Takashi Semba, Noriko Yasuda-Yoshihara, Kosuke Yamada, Akiho Nishimura, Luke Bu

JCI Insight· October 2023

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A novel tdTomato transgenic mouse model to visualize FAP-positive cancer-associated fibroblasts.
Feng Wei, Tomoyuki Uchihara, Atsuko Yonemura, Noriko Yasuda-Yoshihara, Tadahito Yasuda, Luke Bu

FEBS J· May 2023

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IL-1β derived from mixed-polarized macrophages activates fibroblasts and synergistically forms a cancer-promoting microenvironment.
Jun Zhang, Lingfeng Fu, Noriko Yasuda-Yoshihara, Atsuko Yonemura, Feng Wei, Luke Bu

Gastric Cancer· March 2023

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Tumor microenvironmental 15-PGDH depletion promotes fibrotic tumor formation and angiogenesis in pancreatic cancer.
Luke Bu, Atsuko Yonemura, Noriko Yasuda-Yoshihara, Tomoyuki Uchihara, Galym Ismagulov

Cancer Sci· October 2022

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Intracellular MUC20 variant 2 maintains mitochondrial calcium homeostasis and enhances drug resistance in gastric cancer.
Lingfeng Fu, Atsuko Yonemura, Noriko Yasuda-Yoshihara, Terumasa Umemoto, Jun Zhang, Luke Bu

Gastric Cancer· May 2022

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Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer.
Rumi Itoyama, Noriko Yasuda-Yoshihara, Fumimasa Kitamura, Tadahito Yasuda, Luke Bu

Cancer Lett· December 2021

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Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination.
Tadahito Yasuda, Mayu Koiwa, Atsuko Yonemura, Keisuke Miyake, Ryusho Kariya, Luke Bu

Cell Rep· February 2021

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The effect of smoking on chronic inflammation, immune function and blood cell composition.
Ingrid Elisia, Vivian Lam, Brandon Cho, Mariah Hay, Michael Yu Li, Luke Bu

Sci Rep· November 2020

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Functional diversity of cancer-associated fibroblasts in modulating drug resistance.
Luke Bu, Hideo Baba, Tadahito Yasuda, Tomoyuki Uchihara, Takatsugu Ishimoto

Cancer Sci· October 2020

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Exploratory examination of inflammation state, immune response and blood cell composition in a human obese cohort to identify potential markers predicting cancer risk.
Ingrid Elisia, Vivian Lam, Brandon Cho, Mariah Hay, Michael Yu Li, Luke Bu

PLoS One· May 2020

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Gastric Cancer Stem Cells: Current Insights into the Immune Microenvironment and Therapeutic Targets.
Lingfeng Fu, Luke Bu, Tadahito Yasuda, Mayu Koiwa, Takahiko Akiyama

Biomedicines· January 2020

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Biological heterogeneity and versatility of cancer-associated fibroblasts in the tumor microenvironment.
Luke Bu, Hideo Baba, Naoya Yoshida, Keisuke Miyake, Tadahito Yasuda

Oncogene· June 2019

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UV Light-inactivated HSV-1 Stimulates Natural Killer Cell-induced Killing of Prostate Cancer Cells.
Ismael Samudio, Elyse Hofs, Brandon Cho, Michael Li, Kayla Bolduc, Luke Bu

J Immunother· June 2019

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Inhibition of 15-PGDH causes Kras-driven tumor expansion through prostaglandin E2-ALDH1 signaling in the pancreas.
Kota Arima, Masaki Ohmuraya, Keisuke Miyake, Mayu Koiwa, Tomoyuki Uchihara, Luke Bu

Oncogene· February 2019

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Downregulation of 15-hydroxyprostaglandin dehydrogenase by interleukin-1β from activated macrophages leads to poor prognosis in pancreatic cancer.
Kota Arima, Yoshihiro Komohara, Luke Bu, Masayo Tsukamoto, Rumi Itoyama

Cancer Sci· February 2018

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Effect of age on chronic inflammation and responsiveness to bacterial and viral challenges.
Ingrid Elisia, Vivian Lam, Elyse Hofs, Michael Yu Li, Mariah Hay, Luke Bu

PLoS One· January 2018

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Monitor Polyimide Production from Diamine and Dianhydride Reactions Using a Combination of In Situ Infrared and Raman Spectroscopy.
Xiaoyun Chen, Qing Min Wang, Luke Bu

Appl Spectrosc· September 2017

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UV-inactivated HSV-1 potently activates NK cell killing of leukemic cells.
Ismael Samudio, Katayoun Rezvani, Hila Shaim, Elyse Hofs, Mor Ngom, Luke Bu

Blood· May 2016

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Tumour-specific triple-regulated oncolytic herpes virus to target glioma.
Zahid M Delwar, Guoyu Liu, Yvonne Kuo, Cleo Lee, Luke Bu

Oncotarget· May 2016

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Transcriptional and translational dual-regulated oncolytic herpes simplex virus type 1 for targeting prostate tumors.
Cleo Y F Lee, Luke X X Bu, Arrigo DeBenedetti, B Jill Williams, Paul S Rennie

Mol Ther· May 2010

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20S-protopanaxadiol inhibits P-glycoprotein in multidrug resistant cancer cells.
Yan Zhao, Luke Bu, Hang Yan, William Jia

Planta Med· August 2009

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