Publications by authors named "Linjie Han"

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Breaking the Toxicity-Efficacy Dilemma of Polymyxins: Advances in Synergists.
Zhiyan Cai, Yang Zhang, Yuqiao Xin, Linjie Han, Benao Xu, Yongshan Zhao

ACS Infect Dis· December 2025

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Identification of small covalent inhibitors targeting DsbA using virtual screening, covalent docking, and molecular dynamics simulations.
Yuxiang Ren, Yuqiao Xin, Rongxi Zhu, Yang Zhang, Linjie Han, Yongshan Zhao

J Mol Graph Model· June 2025

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Selective Reduction of Cysteine Mutant Antibodies for Site-Specific Antibody-Drug Conjugates.
Xiaoli Liao, Anthony Haight, Dennie Welch, Linjie Han

Bioconjug Chem· December 2023

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Automated Capillary Isoelectric Focusing-Mass Spectrometry with Ultrahigh Resolution for Characterizing Microheterogeneity and Isoelectric Points of Intact Protein Complexes.
Tian Xu, Linjie Han, Liangliang Sun

Anal Chem· July 2022

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An improved capillary isoelectric focusing-mass spectrometry method for high-resolution characterization of monoclonal antibody charge variants.
Tian Xu, Linjie Han, Alayna M George Thompson, Liangliang Sun

Anal Methods· January 2022

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High-Throughput Multi-attribute Analysis of Antibody-Drug Conjugates Enabled by Trapped Ion Mobility Spectrometry and Top-Down Mass Spectrometry.
Eli J Larson, David S Roberts, Jake A Melby, Kevin M Buck, Yanlong Zhu, Linjie Han, Qunying Zhang

Anal Chem· July 2021

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Conjugation Site Analysis by MS/MS Protein Sequencing.
Linjie Han, Yanqun Zhao, Qunying Zhang

Methods Mol Biol· January 2021

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Rapid Analysis of Reduced Antibody Drug Conjugate by Online LC-MS/MS with Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.
Eli J Larson, Yanlong Zhu, Zhijie Wu, Bifan Chen, Zhaorui Zhang, Linjie Han, Qunying Zhang

Anal Chem· November 2020

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Impact of linker-drug on ion exchange chromatography separation of antibody-drug conjugates.
Zhaorui Zhang, Shiyue Zhou, Linjie Han, Qunying Zhang, Wayne A Pritts

MAbs· January 2020

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Collision Induced Unfolding of Intact Antibodies: Rapid Characterization of Disulfide Bonding Patterns, Glycosylation, and Structures.
Yuwei Tian, Linjie Han, Adam C Buckner, Brandon T Ruotolo

Anal Chem· November 2015

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Ion Mobility-Mass Spectrometry Differentiates Protein Quaternary Structures Formed in Solution and in Electrospray Droplets.
Linjie Han, Brandon T Ruotolo

Anal Chem· July 2015

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Collisional and Coulombic unfolding of gas-phase proteins: high correlation to their domain structures in solution.
Yueyang Zhong, Linjie Han, Brandon T Ruotolo

Angew Chem Int Ed Engl· August 2014

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Analysis of a soluble (UreD:UreF:UreG)2 accessory protein complex and its interactions with Klebsiella aerogenes urease by mass spectrometry.
Mark A Farrugia, Linjie Han, Yueyang Zhong, Jodi L Boer, Brandon T Ruotolo

J Am Soc Mass Spectrom· September 2013

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Hofmeister salts recover a misfolded multiprotein complex for subsequent structural measurements in the gas phase.
Linjie Han, Brandon T Ruotolo

Angew Chem Int Ed Engl· August 2013

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Dramatically stabilizing multiprotein complex structure in the absence of bulk water using tuned Hofmeister salts.
Linjie Han, Suk-Joon Hyung, Brandon T Ruotolo

Faraday Discuss· July 2013

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Traveling-wave Ion Mobility-Mass Spectrometry Reveals Additional Mechanistic Details in the Stabilization of Protein Complex Ions through Tuned Salt Additives.
Linjie Han, Brandon T Ruotolo

Int J Ion Mobil Spectrom· March 2013

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Bound cations significantly stabilize the structure of multiprotein complexes in the gas phase.
Linjie Han, Suk-Joon Hyung, Brandon T Ruotolo

Angew Chem Int Ed Engl· June 2012

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Bound anions differentially stabilize multiprotein complexes in the absence of bulk solvent.
Linjie Han, Suk-Joon Hyung, Jonathan J S Mayers, Brandon T Ruotolo

J Am Chem Soc· July 2011

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