Publications by authors named "Linjing Mu"

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Sex-specific cardiac ageing and sympathetic compensation: a translational study.
Achi Haider, Susan Bengs, Angela Portmann, Pimrapat Gebert, Alexia Rossi, Muriel Grämer, Linjing Mu

Eur Heart J· December 2025

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Clinical and molecular correlates of limbic age-related TDP-43 encephalopathy (LATE) F-FDG-PET pattern in amnestic mild cognitive impairment.
Cecilia Boccalini, Luisa Knappe, Gregory Mathoux, Debora Elisa Peretti, Federica Ribaldi, Linjing Mu

Eur J Nucl Med Mol Imaging· November 2025

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Preclinical development of [F]TAAR1-2203 as a PET radioligand for imaging TAAR1 expression and receptor occupancy.
Achi Haider, Zhiwei Xiao, Jiahui Chen, Stefanie K Pfister, Xin Zhou, Linjing Mu

Eur J Nucl Med Mol Imaging· November 2025

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Alpha-synuclein interacts with regulators of ATP homeostasis in mitochondria.
Tetiana Serdiuk, Yanick Fleischmann, Dhiman Ghosh, Aro Delparente, Viviane Reber, Linjing Mu

Nat Commun· August 2025

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Discovery of 1,3,4-Oxadiazin-5-One Derivative CJ1-34 as a Partial ATP Synthase Inhibitor for CNS Applications.
Caitlin V M L Jie, Aro Delparente, Lisa Reichert, Manuela Albrecht, Kenneth Atz, Linjing Mu

Chemistry· April 2025

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Exploration of (R)-[C]YH168 as a PET tracer for imaging monoacylglycerol lipase in the brain: from mice to non-human primates.
Yingfang He, MingQiang Zheng, Jiwei Gu, Lisa Reichert, Johannes Trimborn, Linjing Mu

Eur J Nucl Med Mol Imaging· March 2025

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Highly Specific Miniaturized Fluorescent Monoacylglycerol Lipase Probes Enable Translational Research.
Axel Hentsch, Mónica Guberman, Silke Radetzki, Sofia Kaushik, Mirjam Huizenga, Linjing Mu

J Am Chem Soc· March 2025

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[F]NP3-627, a Candidate PET Imaging Agent Targeting the NLRP3 Inflammasome in the Central Nervous System.
David M Whitehead, Christian Fischer, Emmanuelle Briard, Christopher J Farady, Nadège Graveleau, Linjing Mu

ChemMedChem· February 2025

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Sex differences in the association of Alzheimer's disease biomarkers and cognition in a multicenter memory clinic study.
Cecilia Boccalini, Debora Elisa Peretti, Max Scheffler, Linjing Mu, Alessandra Griffa

Alzheimers Res Ther· February 2025

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Age- and sex-specific differences in myocardial sympathetic tone and left ventricular remodeling following myocardial injury.
Achi Haider, Susan Bengs, Angela Portmann, Sandro Fröhlich, Dominik Etter, Linjing Mu

Biol Sex Differ· January 2025

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Development of radiofluorinated MLN-4760 derivatives for PET imaging of the SARS-CoV-2 entry receptor ACE2.
Jinling Wang, Darja Beyer, Christian Vaccarin, Yingfang He, Matthias Tanriver, Linjing Mu

Eur J Nucl Med Mol Imaging· December 2024

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Towards imaging the immune state of cancer by PET: Targeting legumain with C-labeled P1-Asn peptidomimetics carrying a cyano-warhead.
Severin K Lustenberger, Claudia A Castro Jaramillo, Lena A Bärtschi, Rich Williams, Roger Schibli, Linjing Mu

Nucl Med Biol· December 2024

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Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects.
Johannes Aebi, Kenneth Atz, Simon M Ametamey, Jörg Benz, Julie Blaising, Linjing Mu

Chimia (Aarau)· August 2024

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Preclinical Evaluation of the Reversible Monoacylglycerol Lipase PET Tracer (R)-[C]YH132: Application in Drug Development and Neurodegenerative Diseases.
Yingfang He, Aro Delparente, Caitlin V M L Jie, Claudia Keller, Roland Humm, Linjing Mu

Chembiochem· April 2024

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Identification of ()-[F]YH134 for Monoacylglycerol Lipase Neuroimaging and Exploration of Its Use for Central Nervous System and Peripheral Drug Development.
Yingfang He, Stefanie D Krämer, Uwe Grether, Matthias B Wittwer, Ludovic Collin, Linjing Mu

J Nucl Med· February 2024

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The impact of tau deposition and hypometabolism on cognitive impairment and longitudinal cognitive decline.
Cecilia Boccalini, Federica Ribaldi, Ines Hristovska, Annachiara Arnone, Débora Elisa Peretti, Linjing Mu

Alzheimers Dement· January 2024

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Metabotropic glutamate receptor 5 (mGluR5) is associated with neurodegeneration and amyloid deposition in Alzheimer's disease: A [F]PSS232 PET/MRI study.
Jie Wang, Yingfang He, Xing Chen, Lin Huang, Junpeng Li, Linjing Mu

Alzheimers Res Ther· January 2024

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Proof-of-concept optimization of a copper-mediated F-radiosynthesis of a novel MAGL PET tracer on a high-throughput microdroplet platform and its macroscale translation.
Yingqing Lu, Yingfang He, Roger Schibli, Linjing Mu, R Michael van Dam

Lab Chip· October 2023

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Reducing kidney uptake of radiolabelled exendin-4 using variants of the renally cleavable linker MVK.
Belinda Trachsel, Giulia Valpreda, Alexandra Lutz, Roger Schibli, Linjing Mu

EJNMMI Radiopharm Chem· September 2023

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Imaging increased metabolism in the spinal cord in mice after middle cerebral artery occlusion.
Ruiqing Ni, Nadja Straumann, Serana Fazio, Xose Luis Dean-Ben, Georgios Louloudis, Linjing Mu

Photoacoustics· August 2023

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ATN profile classification across two independent prospective cohorts.
Débora E Peretti, Federica Ribaldi, Max Scheffler, Linjing Mu, Valerie Treyer

Front Med (Lausanne)· July 2023

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and Evaluation of ABCG2 (BCRP) Inhibitors Derived from Ko143.
Melanie Zechner, Claudia A Castro Jaramillo, Nadine S Zubler, Marco F Taddio, Linjing Mu

J Med Chem· May 2023

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Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain.
Yingfang He, Uwe Grether, Marco F Taddio, Carla Meier, Claudia Keller, Annemarieke G J Postmus, Linjing Mu

Eur J Med Chem· December 2022

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Dual MVK cleavable linkers effectively reduce renal retention of In-fibronectin-binding peptides.
Giulia Valpreda, Belinda Trachsel, Viola Vogel, Roger Schibli, Linjing Mu

Bioorg Med Chem· November 2022

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Evaluation of cannabinoid type 2 receptor expression and pyridine-based radiotracers in brains from a mouse model of Alzheimer's disease.
Vasil Kecheliev, Francesco Spinelli, Adrienne Herde, Achi Haider, Linjing Mu

Front Aging Neurosci· September 2022

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