Publications by authors named "Linus Backert"

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HLA Ligand Atlas DIA: extending the benign immunopeptidomics resource with increased sensitivity through data-independent acquisition mass spectrometry.
Leon Bichmann, Ana Marcu, Daniel Johannes Kowalewski, Lena Katharina Freudenmann, Linus Backert

J Immunother Cancer· August 2025

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Autologous T cell therapy for PRAME advanced solid tumors in HLA-A*02 patients: a phase 1 trial.
Martin Wermke, Dejka M Araujo, Manik Chatterjee, Apostolia M Tsimberidou, Tobias A W Holderried, Linus Backert

Nat Med· July 2025

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Author Correction: Autologous T cell therapy for PRAME advanced solid tumors in HLA-A*02 patients: a phase 1 trial.
Martin Wermke, Dejka M Araujo, Manik Chatterjee, Apostolia M Tsimberidou, Tobias A W Holderried, Linus Backert

Nat Med· July 2025

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First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors.
Martin Wermke, Tobias A W Holderried, Jason John Luke, Van K Morris, Winfried H Alsdorf, Linus Backert

J Immunother Cancer· July 2024

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Feasibility and Safety of Personalized, Multi-Target, Adoptive Cell Therapy (IMA101): First-in-Human Clinical Trial in Patients with Advanced Metastatic Cancer.
Apostolia M Tsimberidou, Kerstin Guenther, Borje S Andersson, Regina Mendrzyk, Amir Alpert, Linus Backert

Cancer Immunol Res· July 2023

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Pitfalls in HLA Ligandomics-How to Catch a Li(e)gand.
Jens Fritsche, Daniel J Kowalewski, Linus Backert, Frederik Gwinner, Sonja Dorner

Mol Cell Proteomics· March 2022

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HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy.
Ana Marcu, Leon Bichmann, Leon Kuchenbecker, Daniel Johannes Kowalewski, Lena Katharina Freudenmann, Linus Backert

J Immunother Cancer· April 2021

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Integrative -omics and HLA-ligandomics analysis to identify novel drug targets for ccRCC immunotherapy.
Anna Reustle, Moreno Di Marco, Carolin Meyerhoff, Annika Nelde, Juliane S Walz, Linus Backert

Genome Med· March 2020

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A new synthetic toll-like receptor 1/2 ligand is an efficient adjuvant for peptide vaccination in a human volunteer.
Hans-Georg Rammensee, Karl-Heinz Wiesmüller, P Anoop Chandran, Henning Zelba, Elisa Rusch, Linus Backert

J Immunother Cancer· November 2019

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AureoWiki ̵ The repository of the Staphylococcus aureus research and annotation community.
Stephan Fuchs, Henry Mehlan, Jörg Bernhardt, André Hennig, Stephan Michalik, Linus Backert

Int J Med Microbiol· August 2018

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Favorable immune signature in CLL patients, defined by antigen-specific T-cell responses, might prevent second skin cancers.
Juliane Sarah Walz, Daniel Johannes Kowalewski, Linus Backert, Annika Nelde, Oliver Kohlbacher

Leuk Lymphoma· August 2018

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Mapping the HLA Ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation.
Markus W Löffler, Daniel J Kowalewski, Linus Backert, Jörg Bernhardt, Patrick Adam

Cancer Res· August 2018

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The natural HLA ligandome of glioblastoma stem-like cells: antigen discovery for T cell-based immunotherapy.
Marian Christoph Neidert, Daniel Johannes Kowalewski, Manuela Silginer, Konstantina Kapolou, Linus Backert

Acta Neuropathol· June 2018

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HLA ligandome analysis of primary chronic lymphocytic leukemia (CLL) cells under lenalidomide treatment confirms the suitability of lenalidomide for combination with T-cell-based immunotherapy.
Annika Nelde, Daniel J Kowalewski, Linus Backert, Heiko Schuster, Jan-Ole Werner

Oncoimmunology· February 2018

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The immunopeptidomic landscape of ovarian carcinomas.
Heiko Schuster, Janet K Peper, Hans-Christian Bösmüller, Kevin Röhle, Linus Backert

Proc Natl Acad Sci U S A· November 2017

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Unveiling the Peptide Motifs of HLA-C and HLA-G from Naturally Presented Peptides and Generation of Binding Prediction Matrices.
Moreno Di Marco, Heiko Schuster, Linus Backert, Michael Ghosh, Hans-Georg Rammensee

J Immunol· October 2017

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Safety and immunogenicity of a mRNA rabies vaccine in healthy adults: an open-label, non-randomised, prospective, first-in-human phase 1 clinical trial.
Martin Alberer, Ulrike Gnad-Vogt, Henoch Sangjoon Hong, Keyvan Tadjalli Mehr, Linus Backert

Lancet· September 2017

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Characterization of the Canine MHC Class I DLA-88*50101 Peptide Binding Motif as a Prerequisite for Canine T Cell Immunotherapy.
Sharon M Barth, Christian M Schreitmüller, Franziska Proehl, Kathrin Oehl, Leonie M Lumpp, Linus Backert

PLoS One· July 2017

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A meta-analysis of HLA peptidome composition in different hematological entities: entity-specific dividing lines and "pan-leukemia" antigens.
Linus Backert, Daniel Johannes Kowalewski, Simon Walz, Heiko Schuster, Claudia Berlin

Oncotarget· July 2017

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Haploidentical hematopoietic cell transplantation using in vitro T cell depleted grafts as salvage therapy in patients with disease relapse after prior allogeneic transplantation.
Sebastian P Haen, Christiane Groh, Michael Schumm, Linus Backert, Markus W Löffler

Ann Hematol· May 2017

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Distinct transcriptional changes in non-small cell lung cancer patients associated with multi-antigenic RNActive® CV9201 immunotherapy.
Henoch S Hong, Sven D Koch, Birgit Scheel, Ulrike Gnad-Vogt, Andreas Schröder, Linus Backert

Oncoimmunology· November 2016

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Immunoinformatics and epitope prediction in the age of genomic medicine.
Linus Backert, Oliver Kohlbacher

Genome Med· November 2015

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The antigenic landscape of multiple myeloma: mass spectrometry (re)defines targets for T-cell-based immunotherapy.
Simon Walz, Juliane S Stickel, Daniel Johannes Kowalewski, Heiko Schuster, Katja Weisel, Linus Backert

Blood· September 2015

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HLA ligandome analysis identifies the underlying specificities of spontaneous antileukemia immune responses in chronic lymphocytic leukemia (CLL).
Daniel J Kowalewski, Heiko Schuster, Linus Backert, Claudia Berlin, Stefan Kahn

Proc Natl Acad Sci U S A· January 2015

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ToxDBScan: Large-scale similarity screening of toxicological databases for drug candidates.
Michael Römer, Linus Backert, Johannes Eichner, Andreas Zell

Int J Mol Sci· October 2014

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