Publications by authors named "Linus O Johannissen"

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E
Expanding the substrate scope of a bacterial monoterpene synthase for the production of sesquiterpenoid and diterpenoid products.
Nicole G H Leferink, Joshua N Whitehead, Linus O Johannissen, Nigel S Scrutton

FEBS J· October 2025

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Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]-Cycloadditions.
Chuanjie Sun, Anna R Kohn, Ross Smithson, Florence J Hardy, Jonathan S Trimble, Linus O Johannissen

Angew Chem Int Ed Engl· August 2025

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Conformational Sampling during the Reaction of the SARS-CoV-2 Methyltransferase nsp16.
Yuanxin Cao, James D Green, Linus O Johannissen, Sam Hay

J Phys Chem B· August 2025

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Engineered enzymes for enantioselective nucleophilic aromatic substitutions.
Thomas M Lister, George W Roberts, Euan J Hossack, Fei Zhao, Ashleigh J Burke, Linus O Johannissen

Nature· March 2025

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A Machine Learning Model for the Prediction of Water Contact Angles on Solid Polymers.
Jose Sena, Linus O Johannissen, Jonny J Blaker, Sam Hay

J Phys Chem B· March 2025

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Directed Evolution's Selective Use of Quantum Tunneling in Designed Enzymes─A Combined Theoretical and Experimental Study.
Kseniia Korchagina, Sree Ganesh Balasubramani, Jordan Berreur, Emilie F Gerard, Linus O Johannissen

J Phys Chem B· February 2025

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Mechanistic implications of the ternary complex structural models for the photoenzyme protochlorophyllide oxidoreductase.
Aoife Taylor, Shaowei Zhang, Linus O Johannissen, Michiyo Sakuma, Robert S Phillips

FEBS J· April 2024

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A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme.
Amy E Hutton, Jake Foster, Rebecca Crawshaw, Florence J Hardy, Linus O Johannissen

Nat Commun· March 2024

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Photocobilins integrate B and bilin photochemistry for enzyme control.
Shaowei Zhang, Laura N Jeffreys, Harshwardhan Poddar, Yuqi Yu, Chuanyang Liu, Linus O Johannissen

Nat Commun· March 2024

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Decoding Catalysis by Terpene Synthases.
Joshua N Whitehead, Nicole G H Leferink, Linus O Johannissen, Sam Hay, Nigel S Scrutton

ACS Catal· October 2023

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Redox driven B-ligand switch drives CarH photoresponse.
Harshwardhan Poddar, Ronald Rios-Santacruz, Derren J Heyes, Muralidharan Shanmugam, Adam Brookfield, Linus O Johannissen

Nat Commun· August 2023

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How Is Substrate Halogenation Triggered by the Vanadium Haloperoxidase from ?
Emilie F Gérard, Thirakorn Mokkawes, Linus O Johannissen, Jim Warwicker, Reynard R Spiess

ACS Catal· June 2023

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Photoinduced Electron Transfer from a 1,4,5,6-Tetrahydro Nicotinamide Adenine Dinucleotide (Phosphate) Analogue to Oxidized Flavin in an Ene-Reductase Flavoenzyme.
Magnus Speirs, Samantha J O Hardman, Andreea I Iorgu, Linus O Johannissen, Derren J Heyes

J Phys Chem Lett· April 2023

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A Vitamin B -Photocatalysed Approach to Methionine Analogues.
Oliver J Knowles, Linus O Johannissen, Giacomo E M Crisenza, Sam Hay, David Leys

Angew Chem Int Ed Engl· December 2022

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A Vitamin B-Photocatalysed Approach to Methionine Analogues.
Oliver J Knowles, Linus O Johannissen, Giacomo E M Crisenza, Sam Hay, David Leys

Angew Chem Weinheim Bergstr Ger· December 2022

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Mechanism of Action of Flavin-Dependent Halogenases.
Rhys D Barker, Yuqi Yu, Leonardo De Maria, Linus O Johannissen, Nigel S Scrutton

ACS Catal· December 2022

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Chelator-Based Parameterization of the 12-6-4 Lennard-Jones Molecular Mechanics Potential for More Realistic Metal Ion-Protein Interactions.
Paulius Kantakevičius, Calvin Mathiah, Linus O Johannissen, Sam Hay

J Chem Theory Comput· April 2022

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How Photoactivation Triggers Protochlorophyllide Reduction: Computational Evidence of a Stepwise Hydride Transfer during Chlorophyll Biosynthesis.
Linus O Johannissen, Aoife Taylor, Samantha J O Hardman, Derren J Heyes, Nigel S Scrutton

ACS Catal· April 2022

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Publisher Correction: Photocatalysis as the 'master switch' of photomorphogenesis in early plant development.
Derren J Heyes, Shaowei Zhang, Aoife Taylor, Linus O Johannissen, Samantha J O Hardman

Nat Plants· May 2021

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Interplay between chromophore binding and domain assembly by the B-dependent photoreceptor protein, CarH.
Inês S Camacho, Rachelle Black, Derren J Heyes, Linus O Johannissen, Lennart A I Ramakers

Chem Sci· May 2021

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Photocatalysis as the 'master switch' of photomorphogenesis in early plant development.
Derren J Heyes, Shaowei Zhang, Aoife Taylor, Linus O Johannissen, Samantha J O Hardman

Nat Plants· March 2021

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Predicting new protein conformations from molecular dynamics simulation conformational landscapes and machine learning.
Yiming Jin, Linus O Johannissen, Sam Hay

Proteins· February 2021

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Dual role of the active site 'lid' regions of protochlorophyllide oxidoreductase in photocatalysis and plant development.
Shaowei Zhang, Alan R F Godwin, Aoife Taylor, Samantha J O Hardman, Thomas A Jowitt, Linus O Johannissen

FEBS J· January 2021

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Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches.
Laura N Jeffreys, Kamila J Pacholarz, Linus O Johannissen, Hazel M Girvan, Perdita E Barran

J Biol Chem· May 2020

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Taming the Reactivity of Monoterpene Synthases To Guide Regioselective Product Hydroxylation.
Nicole G H Leferink, Kara E Ranaghan, Jaime Battye, Linus O Johannissen, Sam Hay

Chembiochem· April 2020

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