Publications by authors named "Lisa Checkley"

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Optimization of Prodiginines as Single-Dose Curative Antimalarials.
Amrendra Kumar, Yuexin Li, Xiaowei Zhang, Mahesh Gaddam, Diana Caridha, Lisa Checkley

J Med Chem· November 2025

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Measuring growth, resistance, and recovery after artemisinin treatment of Plasmodium falciparum in a single semi-high-throughput assay.
Mackenzie A C Sievert, Tarrick Qahash, Puspendra P Singh, Douglas A Shoue, Lisa A Checkley

Malar J· August 2025

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The extended recovery ring-stage survival assay is a scalable alternative for artemisinin susceptibility phenotyping of fresh isolates.
Martin Okitwi, Douglas A Shoue, Lisa A Checkley, Stephen Orena, Frida G Ceja

Antimicrob Agents Chemother· December 2024

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Measuring Growth, Resistance, and Recovery after Artemisinin Treatment of Plasmodium falciparum in a single semi-high-throughput Assay.
Mackenzie A C Sievert, Puspendra P Singh, Douglas A Shoue, Lisa A Checkley, Katelyn M Brenneman

bioRxiv· November 2024

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A genetic cross reveals the contributions of and to piperaquine drug resistance.
John Kane, Xue Li, Sudhir Kumar, Katrina A Button-Simons, Katelyn M Vendrely Brenneman, Lisa A Checkley

mBio· July 2024

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A genetic cross reveals the contributions of and to piperaquine drug resistance.
John Kane, Xue Li, Sudhir Kumar, Katrina A Button-Simons, Katelyn M Vendrely Brenneman, Lisa A Checkley

bioRxiv· September 2023

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Chloroquine resistance evolution in Plasmodium falciparum is mediated by the putative amino acid transporter AAT1.
Alfred Amambua-Ngwa, Katrina A Button-Simons, Xue Li, Sudhir Kumar, Katelyn Vendrely Brenneman, Lisa A Checkley

Nat Microbiol· July 2023

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Synthesis and antimalarial activity of amide and ester conjugates of siderophores and ozonides.
Rohit Tiwari, Lisa Checkley, Michael T Ferdig, Jonathan L Vennerstrom, Marvin J Miller

Biometals· April 2023

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A Malaria Parasite Cross Reveals Genetic Determinants of Growth in Different Culture Media.
Sudhir Kumar, Xue Li, Marina McDew-White, Ann Reyes, Elizabeth Delgado, Lisa A Checkley

Front Cell Infect Microbiol· June 2022

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Optimizing bulk segregant analysis of drug resistance using genetic crosses conducted in humanized mice.
Katelyn Vendrely Brenneman, Xue Li, Sudhir Kumar, Elizabeth Delgado, Lisa A Checkley

iScience· April 2022

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The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice.
Katrina A Button-Simons, Sudhir Kumar, Nelly Carmago, Meseret T Haile, Catherine Jett, Lisa A Checkley

Commun Biol· June 2021

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The extended recovery ring-stage survival assay provides a superior association with patient clearance half-life and increases throughput.
Sage Z Davis, Puspendra P Singh, Katelyn M Vendrely, Douglas A Shoue, Lisa A Checkley

Malar J· January 2020

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Leveraging crowdsourcing to accelerate global health solutions.
Sage Davis, Katrina Button-Simons, Taoufik Bensellak, Eren Mehmet Ahsen, Lisa Checkley

Nat Biotechnol· August 2019

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Pairwise growth competitions identify relative fitness relationships among artemisinin resistant Plasmodium falciparum field isolates.
Abigail R Tirrell, Katelyn M Vendrely, Lisa A Checkley, Sage Z Davis, Marina McDew-White

Malar J· August 2019

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Simultaneous genome-wide gene expression and transcript isoform profiling in the human malaria parasite.
Lindsey B Turnbull, Geoffrey H Siwo, Katrina A Button-Simons, Asako Tan, Lisa A Checkley

PLoS One· November 2017

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Antiplasmodial activity of targeted zinc(II)-dipicolylamine complexes.
Douglas R Rice, María de Lourdes Betancourt Mendiola, Claribel Murillo-Solano, Lisa A Checkley, Michael T Ferdig

Bioorg Med Chem· May 2017

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Garcinol Inhibits GCN5-Mediated Lysine Acetyltransferase Activity and Prevents Replication of the Parasite Toxoplasma gondii.
Victoria Jeffers, Hongyu Gao, Lisa A Checkley, Yunlong Liu, Michael T Ferdig

Antimicrob Agents Chemother· April 2016

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An integrative analysis of small molecule transcriptional responses in the human malaria parasite Plasmodium falciparum.
Geoffrey H Siwo, Roger S Smith, Asako Tan, Katrina A Button-Simons, Lisa A Checkley

BMC Genomics· December 2015

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Guanabenz repurposed as an antiparasitic with activity against acute and latent toxoplasmosis.
Imaan Benmerzouga, Lisa A Checkley, Michael T Ferdig, Gustavo Arrizabalaga, Ronald C Wek

Antimicrob Agents Chemother· November 2015

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Plasmodium falciparum genetic crosses in a humanized mouse model.
Ashley M Vaughan, Richard S Pinapati, Ian H Cheeseman, Nelly Camargo, Matthew Fishbaugher, Lisa A Checkley

Nat Methods· July 2015

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Predicting functional and regulatory divergence of a drug resistance transporter gene in the human malaria parasite.
Geoffrey H Siwo, Asako Tan, Katrina A Button-Simons, Upeka Samarakoon, Lisa A Checkley

BMC Genomics· February 2015

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Expression of the essential Kinase PfCDPK1 from Plasmodium falciparum in Toxoplasma gondii facilitates the discovery of novel antimalarial drugs.
Rajshekhar Y Gaji, Lisa Checkley, Michael L Reese, Michael T Ferdig, Gustavo Arrizabalaga

Antimicrob Agents Chemother· May 2014

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The landscape of inherited and de novo copy number variants in a Plasmodium falciparum genetic cross.
Upeka Samarakoon, Joseph M Gonzales, Jigar J Patel, Asako Tan, Lisa Checkley

BMC Genomics· September 2011

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Design, synthesis, and study of a mycobactin-artemisinin conjugate that has selective and potent activity against tuberculosis and malaria.
Marvin J Miller, Andrew J Walz, Helen Zhu, Chunrui Wu, Garrett Moraski, Lisa Checkley

J Am Chem Soc· February 2011

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Chloroquine susceptibility and reversibility in a Plasmodium falciparum genetic cross.
Jigar J Patel, Drew Thacker, John C Tan, Perri Pleeter, Lisa Checkley

Mol Microbiol· November 2010

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