Publications by authors named "Lisa D Belmont"

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GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1.
Alexander M Taylor, Chris Bailey, Lisa D Belmont, Robert Campbell, Nico Cantone

J Med Chem· August 2022

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Werner Syndrome Helicase Is Required for the Survival of Cancer Cells with Microsatellite Instability.
Lorn Kategaya, Senthil K Perumal, Jeffrey H Hager, Lisa D Belmont

iScience· March 2019

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Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development.
James J Crawford, Adam R Johnson, Dinah L Misner, Lisa D Belmont, Georgette Castanedo

J Med Chem· March 2018

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Battling Btk Mutants With Noncovalent Inhibitors That Overcome Cys481 and Thr474 Mutations.
Adam R Johnson, Pawan Bir Kohli, Arna Katewa, Emily Gogol, Lisa D Belmont

ACS Chem Biol· October 2016

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Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma Models.
Elizabeth A Punnoose, Joel D Leverson, Franklin Peale, Erwin R Boghaert, Lisa D Belmont

Mol Cancer Ther· May 2016

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Cell biology and the "real world".
Craig Blackstone, Lisa D Belmont

Mol Biol Cell· March 2016

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Structural basis for resistance to diverse classes of NAMPT inhibitors.
Weiru Wang, Kristi Elkins, Angela Oh, Yen-Ching Ho, Jiansheng Wu, Lisa D Belmont

PLoS One· December 2015

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Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy.
Joel D Leverson, Darren C Phillips, Michael J Mitten, Erwin R Boghaert, Dolores Diaz, Lisa D Belmont

Sci Transl Med· March 2015

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Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment.
Eugene Varfolomeev, Anita Izrael-Tomasevic, Kebing Yu, Daisy Bustos, Tatiana Goncharov, Lisa D Belmont

Biochem J· February 2015

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Loss of NAPRT1 expression by tumor-specific promoter methylation provides a novel predictive biomarker for NAMPT inhibitors.
David S Shames, Kristi Elkins, Kimberly Walter, Thomas Holcomb, Pan Du, Lisa D Belmont

Clin Cancer Res· December 2013

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Dependence of tumor cell lines and patient-derived tumors on the NAD salvage pathway renders them sensitive to NAMPT inhibition with GNE-618.
Yang Xiao, Kristi Elkins, Jenni K Durieux, Leslie Lee, Jason Oeh, Lisa D Belmont

Neoplasia· October 2013

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Bcl-2/Bcl-xL inhibition increases the efficacy of MEK inhibition alone and in combination with PI3 kinase inhibition in lung and pancreatic tumor models.
Nguyen Tan, Maureen Wong, Michelle A Nannini, Rebecca Hong, Leslie B Lee, Lisa D Belmont

Mol Cancer Ther· June 2013

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GDC-0941, a novel class I selective PI3K inhibitor, enhances the efficacy of docetaxel in human breast cancer models by increasing cell death in vitro and in vivo.
Jeffrey J Wallin, Jane Guan, Wei Wei Prior, Leslie B Lee, Leanne Berry, Lisa D Belmont

Clin Cancer Res· July 2012

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Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells.
Delphine Mérino, Seong L Khaw, Stefan P Glaser, Daniel J Anderson, Lisa D Belmont

Blood· June 2012

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Navitoclax (ABT-263) reduces Bcl-x(L)-mediated chemoresistance in ovarian cancer models.
Maureen Wong, Nguyen Tan, Jiping Zha, Franklin V Peale, Peng Yue, Lisa D Belmont

Mol Cancer Ther· April 2012

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Navitoclax enhances the efficacy of taxanes in non-small cell lung cancer models.
Nguyen Tan, Mehnaz Malek, Jiping Zha, Peng Yue, Robert Kassees, Lisa D Belmont

Clin Cancer Res· March 2011

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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
Ingrid E Wertz, Saritha Kusam, Cynthia Lam, Toru Okamoto, Wendy Sandoval, Lisa D Belmont

Nature· March 2011

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A chemosensitization screen identifies TP53RK, a kinase that restrains apoptosis after mitotic stress.
David Peterson, James Lee, Xingye C Lei, William F Forrest, David P Davis, Lisa D Belmont

Cancer Res· August 2010

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Antitumor activity of an allosteric inhibitor of centromere-associated protein-E.
Kenneth W Wood, Latesh Lad, Lusong Luo, Xiangping Qian, Steven D Knight, Lisa D Belmont

Proc Natl Acad Sci U S A· March 2010

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