Publications by authors named "Lora Picton"

Claim this Profile
S
Stat5 opposes the transcription factor Tox and rewires exhausted CD8 T cells toward durable effector-like states during chronic antigen exposure.
Jean-Christophe Beltra, Mohamed S Abdel-Hakeem, Sasikanth Manne, Zhen Zhang, Hua Huang, Lora Picton

Immunity· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Overcoming lung cancer immunotherapy resistance by combining nontoxic variants of IL-12 and IL-2.
Brendan L Horton, Alicia D D'Souza, Maria Zagorulya, Chloe V McCreery, Gita C Abhiraman, Lora Picton

JCI Insight· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis.
Naotaka Tsutsumi, Zahra Masoumi, Sophie C James, Julie A Tucker, Hauke Winkelmann, Lora K Picton

Cell· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Receptor Elimination by E3 Ubiquitin Ligase Recruitment (REULR): A Targeted Protein Degradation Toolbox.
Dirk H Siepe, Lora K Picton, K Christopher Garcia

ACS Synth Biol· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo.
Teresa L Ramos, Sara Bolivar-Wagers, Sujeong Jin, Govindarajan Thangavelu, Federico Simonetta, Lora K Picton

Blood· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
IL-2 receptor engineering enhances regulatory T cell function suppressed by calcineurin inhibitor.
Toshihito Hirai, Po-Yu Lin, Teresa L Ramos, Federico Simonetta, Leon L Su, Lora K Picton

Am J Transplant· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Publisher Correction: Potentiating adoptive cell therapy using synthetic IL-9 receptors.
Anusha Kalbasi, Mikko Siurala, Leon L Su, Mito Tariveranmoshabad, Lora K Picton

Nature· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Induced CD45 Proximity Potentiates Natural Killer Cell Receptor Antagonism.
Junming Ren, Yeara Jo, Lora K Picton, Leon L Su, David H Raulet

ACS Synth Biol· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Potentiating adoptive cell therapy using synthetic IL-9 receptors.
Anusha Kalbasi, Mikko Siurala, Leon L Su, Mito Tariveranmoshabad, Lora K Picton

Nature· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design of protein-binding proteins from the target structure alone.
Longxing Cao, Brian Coventry, Inna Goreshnik, Buwei Huang, William Sheffler, Lora Picton

Nature· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synergy of a STING agonist and an IL-2 superkine in cancer immunotherapy against MHC I-deficient and MHC I tumors.
Natalie K Wolf, Cristina Blaj, Lora K Picton, Gail Snyder, Li Zhang

Proc Natl Acad Sci U S A· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Facile discovery of surrogate cytokine agonists.
Michelle Yen, Junming Ren, Qingxiang Liu, Caleb R Glassman, Timothy P Sheahan, Lora K Picton

Cell· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Interleukin-2 superkines by computational design.
Junming Ren, Alexander E Chu, Kevin M Jude, Lora K Picton, Aris J Kare

Proc Natl Acad Sci U S A· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia.
Qian Zhang, Morgan E Hresko, Lora K Picton, Leon Su, Michael J Hollander

Sci Transl Med· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An engineered IL-2 partial agonist promotes CD8 T cell stemness.
Fei Mo, Zhiya Yu, Peng Li, Jangsuk Oh, Rosanne Spolski, Lora K Picton

Nature· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
Caleb R Glassman, Leon Su, Sonia S Majri-Morrison, Hauke Winkelmann, Fei Mo, Lora K Picton

Elife· May 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Selective expansion of regulatory T cells using an orthogonal IL-2/IL-2 receptor system facilitates transplantation tolerance.
Toshihito Hirai, Teresa L Ramos, Po-Yu Lin, Federico Simonetta, Leon L Su, Lora K Picton

J Clin Invest· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Isolation and Analysis of Mitochondrial Fission Enzyme DNM1 from Saccharomyces cerevisiae.
Nolan W Kennedy, Lora K Picton, R Blake Hill

Methods Mol Biol· March 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Immune receptor inhibition through enforced phosphatase recruitment.
Ricardo A Fernandes, Leon Su, Yoko Nishiga, Junming Ren, Aladdin M Bhuiyan, Lora K Picton

Nature· October 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.
Jonathan T Sockolosky, Eleonora Trotta, Giulia Parisi, Lora Picton, Leon L Su

Science· March 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Alternative evolutionary histories in the sequence space of an ancient protein.
Tyler N Starr, Lora K Picton, Joseph W Thornton

Nature· September 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species.
Evan A Bordt, Pascaline Clerc, Brian A Roelofs, Andrew J Saladino, László Tretter, Lora K Picton

Dev Cell· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A designed point mutant in Fis1 disrupts dimerization and mitochondrial fission.
Jonathan P B Lees, Cara Marie Manlandro, Lora K Picton, Alexandra Z Ebie Tan, Salvador Casares

J Mol Biol· October 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evidence for conformational heterogeneity of fission protein Fis1 from Saccharomyces cerevisiae.
Lora K Picton, Salvador Casares, Ann C Monahan, Ananya Majumdar, R Blake Hill

Biochemistry· July 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Role of conserved cysteines in the alphavirus E3 protein.
Megan M Parrott, Sarah A Sitarski, Randy J Arnold, Lora K Picton, R Blake Hill

J Virol· March 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis