Publications by authors named "Luca Cardone"

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Drug Repurposing in Pancreatic Cancer: A Multi-Stakeholder Perspective to Improve Treatment Options for Pancreatic Cancer Patients.
Evelyn Hewitt, Gauthier Bouche, Alexandre Costa Alencar, Stephen J Bigelsen, Raluca Radu, Luca Cardone

Cancer Manag Res· March 2025

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Enhancing PDAC therapy: Decitabine-olaparib synergy targets KRAS-dependent tumors.
Giorgia Anastasio, Michela Felaco, Alessia Lamolinara, Francesco Del Pizzo, Elisa Cacciagrano, Luca Cardone

iScience· February 2025

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DNA demethylation triggers cell free DNA release in colorectal cancer cells.
Valeria Pessei, Marco Macagno, Elisa Mariella, Noemi Congiusta, Vittorio Battaglieri, Luca Cardone

Genome Med· October 2024

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Cancer incidence (2000-2020) among individuals under 35: an emerging sex disparity in oncology.
Alessandro Cavazzani, Claudia Angelini, Dario Gregori, Luca Cardone

BMC Med· September 2024

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Computer-aided drug repurposing for cancer therapy: Approaches and opportunities to challenge anticancer targets.
Carla Mottini, Francesco Napolitano, Zhongxiao Li, Xin Gao, Luca Cardone

Semin Cancer Biol· January 2021

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Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem-Like Cells and Reduces Metastases through Effects on Lipid Anabolism.
Rosanna Dattilo, Carla Mottini, Emanuela Camera, Alessia Lamolinara, Noam Auslander, Luca Cardone

Cancer Res· October 2020

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Beyond the Genomic Mutation: Rethinking the Molecular Biomarkers of K-RAS Dependency in Pancreatic Cancers.
Carla Mottini, Luca Cardone

Int J Mol Sci· July 2020

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Boosting the arsenal against COVID-19 through computational drug repurposing.
Gennaro Ciliberto, Luca Cardone

Drug Discov Today· June 2020

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Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma.
Carla Mottini, Hideo Tomihara, Diego Carrella, Alessia Lamolinara, Manuela Iezzi, Luca Cardone

Cancer Res· November 2019

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Drug repurposing for the treatment of glioblastoma multiforme.
Claudia Abbruzzese, Silvia Matteoni, Michele Signore, Luca Cardone, Kavindra Nath

J Exp Clin Cancer Res· November 2017

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Biocomputing drug repurposing toward targeted therapies.
Luca Cardone

Aging (Albany NY)· November 2016

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Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds.
Diego Carrella, Isabella Manni, Barbara Tumaini, Rosanna Dattilo, Federica Papaccio, Luca Cardone

Oncotarget· September 2016

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Metabolic regulation of the ultradian oscillator Hes1 by reactive oxygen species.
Simona Ventre, Alessia Indrieri, Chiara Fracassi, Brunella Franco, Ivan Conte, Luca Cardone

J Mol Biol· May 2015

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Differential network analysis for the identification of condition-specific pathway activity and regulation.
Gennaro Gambardella, Maria Nicoletta Moretti, Rossella de Cegli, Luca Cardone, Adriano Peron

Bioinformatics· July 2013

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Activation of β-catenin by oncogenic PIK3CA and EGFR promotes resistance to glucose deprivation by inducing a strong antioxidant response.
Luca Cardone, Alberto Bardelli, Vittorio Enrico Avvedimento

PLoS One· December 2012

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Analysis of circadian rhythms in zebrafish.
Jun Hirayama, Maki Kaneko, Luca Cardone, Gregory Cahill, Paolo Sassone-Corsi

Methods Enzymol· November 2008

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PIK3CA-activating mutations and chemotherapy sensitivity in stage II-III breast cancer.
Cornelia Liedtke, Luca Cardone, Attila Tordai, Kai Yan, Henry L Gomez

Breast Cancer Res· July 2008

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Circadian clock control by SUMOylation of BMAL1.
Luca Cardone, Jun Hirayama, Francesca Giordano, Teruya Tamaru, Jorma J Palvimo

Science· August 2005

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Common pathways in circadian and cell cycle clocks: light-dependent activation of Fos/AP-1 in zebrafish controls CRY-1a and WEE-1.
Jun Hirayama, Luca Cardone, Masao Doi, Paolo Sassone-Corsi

Proc Natl Acad Sci U S A· July 2005

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Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD.
Ozkan Yildiz, Masao Doi, Irene Yujnovsky, Luca Cardone, Alex Berndt

Mol Cell· January 2005

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Mitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signaling.
Luca Cardone, Annalisa Carlucci, Adele Affaitati, Alessandra Livigni, Tiziana DeCristofaro

Mol Cell Biol· June 2004

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On the communication pathways between the central pacemaker and peripheral oscillators.
Nicolas Cermakian, Matthew P Pando, Masao Doi, Luca Cardone, Irene Yujnovsky

Novartis Found Symp· February 2004

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Timing the cell cycle.
Luca Cardone, Paolo Sassone-Corsi

Nat Cell Biol· October 2003

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Essential role of A-kinase anchor protein 121 for cAMP signaling to mitochondria.
Adele Affaitati, Luca Cardone, Tiziana de Cristofaro, Annalisa Carlucci, Michael D Ginsberg

J Biol Chem· February 2003

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Hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin prevents cardiac hypertrophy induced by pressure overload and inhibits p21ras activation.
Ciro Indolfi, Emilio Di Lorenzo, Cinzia Perrino, Angela Maria Stingone, Antonio Curcio, Luca Cardone

Circulation· October 2002

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