Publications by authors named "Luca Lazzari"

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The lncRNA ELDR suppresses tumorigenicity of AML by interfering with DNA replication and chromatin accessibility.
Kaifee Arman, Julie Ross, Eva-Maria Piskor, Luca Lazzari, Virginie Calderon

Blood Adv· December 2025

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Total neoadjuvant therapy followed by non-operative management or surgery in stage II-III rectal cancer (NO-CUT): a multicentre, single-arm, phase 2 trial.
Alessio Amatu, Giorgio Patelli, Maria Giulia Zampino, Francesca Bergamo, Stefania Mosconi, Luca Lazzari

Lancet Oncol· December 2025

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The molecular and functional landscape of resistance to FOLFIRI chemotherapy in metastatic colorectal cancer.
Marco Avolio, Simonetta M Leto, Francesco Sassi, Barbara Lupo, Elena Grassi, Luca Lazzari

Cancer Discov· September 2025

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Stain normalization matters: impact on feature relevance and classifier performance in mCRC therapy response prediction.
Giulia Nicoletti, Debora Cafaro, Federica Cruciani, Gianluca Mauri, Luca Lazzari

Annu Int Conf IEEE Eng Med Biol Soc· July 2025

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AI-Driven Pathomics for Predicting Chemotherapy Response in Metastatic Colorectal Cancer: A Transfer Learning Approach with Attention-Based Multiple Instance Learning.
Federica Cruciani, Giulia Nicoletti, Debora Cafaro, Gianluca Mauri, Luca Lazzari

Annu Int Conf IEEE Eng Med Biol Soc· July 2025

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Selective Translation Under Heat Shock: Integrating HSP70 mRNA Regulation with Cellular Stress Responses in Yeast and Mammals.
Talar Ghadanian, Shruti Iyer, Luca Lazzari, Maria Vera

Mol Biol Cell· May 2025

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Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer.
Elena Grassi, Valentina Vurchio, George D Cresswell, Irene Catalano, Barbara Lupo, Luca Lazzari

Sci Transl Med· May 2025

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Clinical utility and future perspectives of liquid biopsy in colorectal cancer.
Giorgio Patelli, Luca Lazzari, Giovanni Crisafulli, Andrea Sartore-Bianchi, Alberto Bardelli

Commun Med (Lond)· April 2025

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A Comparative Study of Methyl-BEAMing and Droplet Digital PCR for Gene Promoter Hypermethylation Detection.
Marco Macagno, Valeria Pessei, Noemi Congiusta, Luca Lazzari, Sara Erika Bellomo

Diagnostics (Basel)· November 2024

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Prediction of homologous recombination deficiency identifies colorectal tumors sensitive to PARP inhibition.
Giorgio Corti, Kristi Buzo, Enrico Berrino, Martina Miotto, Maria Costanza Aquilano, Luca Lazzari

NPJ Precis Oncol· October 2024

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Tuning the Softness of the Pendant Arms and the Polyazamacrocyclic Backbone to Chelate the Pb/Pb Theranostic Pair.
Marianna Tosato, Parmissa Randhawa, Luca Lazzari, Brooke L McNeil, Marco Dalla Tiezza

Inorg Chem· January 2024

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The ribosome quality control factor Asc1 determines the fate of HSP70 mRNA on and off the ribosome.
Lokha R Alagar Boopathy, Emma Beadle, Alan RuoChen Xiao, Aitana Garcia-Bueno Rico, Celia Alecki, Luca Lazzari

Nucleic Acids Res· July 2023

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Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients.
Giovanni Crisafulli, Andrea Sartore-Bianchi, Luca Lazzari, Filippo Pietrantonio, Alessio Amatu

Cancer Discov· July 2022

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Revisiting Lead(II)-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic Acid Coordination Chemistry in Aqueous Solutions: Evidence of an Underestimated Thermodynamic Stability.
Marianna Tosato, Luca Lazzari, Valerio Di Marco

ACS Omega· May 2022

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Delta-Radiomics Predicts Response to First-Line Oxaliplatin-Based Chemotherapy in Colorectal Cancer Patients with Liver Metastases.
Valentina Giannini, Laura Pusceddu, Arianna Defeudis, Giulia Nicoletti, Giovanni Cappello, Luca Lazzari

Cancers (Basel)· January 2022

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Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver.
Alice Bertocchi, Sara Carloni, Paola Simona Ravenda, Giovanni Bertalot, Ilaria Spadoni, Luca Lazzari

Cancer Cell· May 2021

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Amyloid aggregates accumulate in melanoma metastasis modulating YAP activity.
Vittoria Matafora, Francesco Farris, Umberto Restuccia, Simone Tamburri, Giuseppe Martano, Luca Lazzari

EMBO Rep· September 2020

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A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin.
Sabrina Arena, Giorgio Corti, Erika Durinikova, Monica Montone, Nicole M Reilly, Luca Lazzari

Clin Cancer Res· March 2020

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Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer.
Annalisa Lorenzato, Alessandro Magrì, Vittoria Matafora, Valentina Audrito, Pamela Arcella, Luca Lazzari

Cancers (Basel)· March 2020

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Patient-Derived Xenografts and Matched Cell Lines Identify Pharmacogenomic Vulnerabilities in Colorectal Cancer.
Luca Lazzari, Giorgio Corti, Gabriele Picco, Claudio Isella, Monica Montone

Clin Cancer Res· October 2019

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Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer.
Giulia Siravegna, Luca Lazzari, Giovanni Crisafulli, Andrea Sartore-Bianchi, Benedetta Mussolin

Cancer Cell· July 2018

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Reliance upon ancestral mutations is maintained in colorectal cancers that heterogeneously evolve during targeted therapies.
Mariangela Russo, Simona Lamba, Annalisa Lorenzato, Alberto Sogari, Giorgio Corti, Luca Lazzari

Nat Commun· June 2018

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ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer.
Filippo Pietrantonio, Federica Di Nicolantonio, Alexa B Schrock, Jeeyun Lee, Sabine Tejpar, Luca Lazzari

J Natl Cancer Inst· December 2017

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Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer.
Beth O Van Emburgh, Sabrina Arena, Giulia Siravegna, Luca Lazzari, Giovanni Crisafulli

Nat Commun· December 2016

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MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations.
Sabrina Arena, Giulia Siravegna, Benedetta Mussolin, Jeffrey D Kearns, Beni B Wolf, Luca Lazzari

Sci Transl Med· February 2016

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