Publications by authors named "Luca Pignataro"

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Late-stage peptide modification with salicylaldehyde tag enhances affinity for nuclear factor-kappa B essential modulator.
Mattia Mason, Kaliroi Peqini, Federico Uggeri, Diego Rondelli, Sara Sattin, Luca Pignataro

RSC Chem Biol· December 2025

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A Tight Contact: The Expanding Application of Salicylaldehydes in Lysine-Targeting Covalent Drugs.
Mattia Mason, Laura Belvisi, Luca Pignataro, Alberto Dal Corso

Chembiochem· April 2024

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Amine-Carbamate Self-Immolative Spacers Counterintuitively Release 3° Alcohol at Much Faster Rates than 1° Alcohol Payloads.
Mattia Mason, Lydia Bisbal Lopez, Fazel Bashiri, Aurélie Herrero, Aurélien Baron, Luca Pignataro

Chembiochem· April 2024

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Design, Synthesis and Catalytic Activity of (Cyclopentadienone)iron Complexes Containing a Stereogenic Plane and a Stereogenic Axis.
Giovanni Maria Fusi, Tommaso Gandini, Silvia Gazzola, Toni Grell, Valentina Colombo, Luca Pignataro

Chemistry· December 2023

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mass spectrometry-based biodistribution analysis of an antibody-Resiquimod conjugate bearing a protease-cleavable and acid-labile linker.
Lydia Bisbal Lopez, Domenico Ravazza, Matilde Bocci, Aureliano Zana, Lucrezia Principi, Luca Pignataro

Front Pharmacol· December 2023

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Visible Light-Promoted β-Functionalization of Carbonyl Compounds in the Presence of Organic Dyes.
Luigi Dolcini, Tommaso Gandini, Riccardo Castiglioni, Alberto Bossi, Marta Penconi, Luca Pignataro

J Org Chem· October 2023

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RGD Cyclopeptide Equipped with a Lysine-Engaging Salicylaldehyde Showing Enhanced Integrin Affinity and Cell Detachment Potency.
Giovanni Sacco, Daniela Arosio, Mayra Paolillo, Andreas Gloger, Jörg Scheuermann, Luca Pignataro

Chemistry· April 2023

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Advanced Pyrrolidine-Carbamate Self-Immolative Spacer with Tertiary Amine Handle Induces Superfast Cyclative Drug Release.
Alberto Dal Corso, Margaux Frigoli, Martina Prevosti, Mattia Mason, Raffaella Bucci, Luca Pignataro

ChemMedChem· August 2022

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A trifunctional self-immolative spacer enables drug release with two non-sequential enzymatic cleavages.
Alberto Dal Corso, Simone Arosio, Noemi Arrighetti, Paola Perego, Laura Belvisi, Luca Pignataro

Chem Commun (Camb)· August 2021

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Fast Cyclization of a Proline-Derived Self-Immolative Spacer Improves the Efficacy of Carbamate Prodrugs.
Alberto Dal Corso, Valentina Borlandelli, Cristina Corno, Paola Perego, Laura Belvisi, Luca Pignataro

Angew Chem Int Ed Engl· March 2020

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Insight into GEBR-32a: Chiral Resolution, Absolute Configuration and Enantiopreference in PDE4D Inhibition.
Valeria Cavalloro, Katia Russo, Francesca Vasile, Luca Pignataro, Archimede Torretta

Molecules· February 2020

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Innovative Linker Strategies for Tumor-Targeted Drug Conjugates.
Alberto Dal Corso, Luca Pignataro, Laura Belvisi, Cesare Gennari

Chemistry· November 2019

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A dimeric bicyclic RGD ligand displays enhanced integrin binding affinity and strong biological effects on U-373 MG glioblastoma cells.
Giovanni Sacco, Alberto Dal Corso, Daniela Arosio, Laura Belvisi, Mayra Paolillo, Luca Pignataro

Org Biomol Chem· October 2019

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Synthesis and Biological Evaluation of RGD and isoDGR-Monomethyl Auristatin Conjugates Targeting Integrin α β.
André Raposo Moreira Dias, Lizeth Bodero, Ana Martins, Daniela Arosio, Silvia Gazzola, Luca Pignataro

ChemMedChem· May 2019

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β-Glucuronidase triggers extracellular MMAE release from an integrin-targeted conjugate.
Paula López Rivas, Christoph Müller, Christian Breunig, Torsten Hechler, Andreas Pahl, Luca Pignataro

Org Biomol Chem· May 2019

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Rational Design of Antiangiogenic Helical Oligopeptides Targeting the Vascular Endothelial Growth Factor Receptors.
Simone Zanella, Gianfranco Bocchinfuso, Marta De Zotti, Daniela Arosio, Franca Marino, Luca Pignataro

Front Chem· March 2019

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Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin-Targeted Conjugate.
André Raposo Moreira Dias, Arianna Pina, Amelia Dean, Hans-Georg Lerchen, Michele Caruso, Luca Pignataro

Chemistry· February 2019

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Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting.
Lizeth Bodero, Paula López Rivas, Barbara Korsak, Torsten Hechler, Andreas Pahl, Luca Pignataro

Beilstein J Org Chem· February 2018

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Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin α β.
André Raposo Moreira Dias, Arianna Pina, Alberto Dal Corso, Daniela Arosio, Laura Belvisi, Luca Pignataro

Chemistry· October 2017

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Investigating the Interaction of Cyclic RGD Peptidomimetics with αβ₆ Integrin by Biochemical and Molecular Docking Studies.
Monica Civera, Daniela Arosio, Francesca Bonato, Leonardo Manzoni, Luca Pignataro

Cancers (Basel)· September 2017

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Enantioselective Reductions Promoted by (Cyclopentadienone)iron Complexes.
Umberto Piarulli, Sofia Vailati Fachini, Luca Pignataro

Chimia (Aarau)· September 2017

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Tumor Targeting with an isoDGR-Drug Conjugate.
Simone Zanella, Simona Angerani, Arianna Pina, Paula López Rivas, Clelia Giannini, Luca Pignataro

Chemistry· June 2017

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Insights into the Binding of Cyclic RGD Peptidomimetics to αβ Integrin by using Live-Cell NMR And Computational Studies.
Ileana Guzzetti, Monica Civera, Francesca Vasile, Daniela Arosio, Cristina Tringali, Luca Pignataro

ChemistryOpen· February 2017

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Riding the Wave of Monodentate Ligand Revival: From the A/B Concept to Noncovalent Interactions.
Luca Pignataro, Cesare Gennari

Chem Rec· December 2016

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Asymmetric Hydrogenation of 3-Substituted Pyridinium Salts.
Marc Renom-Carrasco, Piotr Gajewski, Luca Pignataro, Johannes G de Vries, Umberto Piarulli

Chemistry· July 2016

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