Publications by authors named "Lucia Vanrell"

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Effective cancer immunotherapy combining mRNA-encoded bispecific antibodies that induce polyclonal T cell engagement and PD-L1-dependent 4-1BB costimulation.
Oana Hangiu, Rocío Navarro, Susana Frago, Laura Rubio-Pérez, Antonio Tapia-Galisteo, Lucía Vanrell

Front Immunol· May 2025

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Discovery and preclinical development of a SdAb-based CAR-T technology for targeting CD33 in AML.
Franco Bernasconi-Bisio, Eva Molina, Vianca Ibarra, Inés Ibáñez-Sala, Federica Rochira, Lucía Vanrell

Mol Ther Oncol· March 2025

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Targeting PD-1 T cells with small-format immunocytokines enhances IL-12 antitumor activity.
Noelia Silva-Pilipich, Uxue Beloki, Patricia Apaolaza, Ana Igea, Laura Salaberry, Lucía Vanrell

Mol Ther· January 2025

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Characterization of a Trispecific PD-L1 Blocking Antibody That Exhibits EGFR-Conditional 4-1BB Agonist Activity.
Laura Rubio-Pérez, Susana Frago, Marta Compte, Rocío Navarro, Seandean L Harwood, Lucía Vanrell

Antibodies (Basel)· April 2024

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Checkpoint blockade meets gene therapy: Opportunities to improve response and reduce toxicity.
Noelia Silva-Pilipich, Ángela Covo-Vergara, Lucía Vanrell, Cristian Smerdou

Int Rev Cell Mol Biol· August 2023

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Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses.
Noelia Silva-Pilipich, Ester Blanco, Teresa Lozano, Eva Martisova, Ana Igea, Lucía Vanrell

Cancer Lett· May 2023

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A Small Virus to Deliver Small Antibodies: New Targeted Therapies Based on AAV Delivery of Nanobodies.
Noelia Silva-Pilipich, Cristian Smerdou, Lucía Vanrell

Microorganisms· September 2021

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Long-Term Systemic Expression of a Novel PD-1 Blocking Nanobody from an AAV Vector Provides Antitumor Activity without Toxicity.
Noelia Silva-Pilipich, Eva Martisova, María Cristina Ballesteros-Briones, Sandra Hervas-Stubbs, Noelia Casares, Lucia Vanrell

Biomedicines· December 2020

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A new generation of vaccines based on alphavirus self-amplifying RNA.
María Cristina Ballesteros-Briones, Noelia Silva-Pilipich, Guillermo Herrador-Cañete, Lucia Vanrell, Cristian Smerdou

Curr Opin Virol· October 2020

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Adeno-Associated Viral Vectors Serotype 8 for Cell-Specific Delivery of Therapeutic Genes in the Central Nervous System.
Diego Pignataro, Diego Sucunza, Lucia Vanrell, Esperanza Lopez-Franco, Iria G Dopeso-Reyes

Front Neuroanat· February 2017

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Complementary Effects of Interleukin-15 and Alpha Interferon Induce Immunity in Hepatitis B Virus Transgenic Mice.
Marianna Di Scala, Itziar Otano, Irene Gil-Fariña, Lucia Vanrell, Mirja Hommel

J Virol· October 2016

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Chronic exposure to IFNα drives medullar lymphopoiesis towards T-cell differentiation in mice.
Marianna Di Scala, Irene Gil-Fariña, Lucia Vanrell, Rodrigo Sánchez-Bayona, Diego Alignani

Haematologica· August 2015

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Recombinant streptavidin nanopeptamer anti-immunocomplex assay for noncompetitive detection of small analytes.
Mariana Carlomagno, Gabriel Lassabe, Martín Rossotti, Andrés González-Techera, Lucía Vanrell

Anal Chem· October 2014

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IL12-mediated liver inflammation reduces the formation of AAV transcriptionally active forms but has no effect over preexisting AAV transgene expression.
Irene Gil-Fariña, Marianna Di Scala, Lucia Vanrell, Cristina Olagüe, Africa Vales

PLoS One· January 2014

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Nanopeptamers for the development of small-analyte lateral flow tests with a positive readout.
Lucía Vanrell, Andrés Gonzalez-Techera, Bruce D Hammock, Gualberto Gonzalez-Sapienza

Anal Chem· January 2013

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Development of a liver-specific Tet-on inducible system for AAV vectors and its application in the treatment of liver cancer.
Lucia Vanrell, Marianna Di Scala, Laura Blanco, Itziar Otano, Irene Gil-Farina

Mol Ther· July 2011

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Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria.
Carmen Unzu, Ana Sampedro, Itsaso Mauleón, Lucía Vanrell, Juan Dubrot

J Hepatol· March 2010

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Effect of adeno-associated virus serotype and genomic structure on liver transduction and biodistribution in mice of both genders.
Astrid Pañeda, Lucia Vanrell, Itsaso Mauleon, Julien S Crettaz, Pedro Berraondo

Hum Gene Ther· August 2009

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