Publications by authors named "Lukas Perkhofer"

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Gallbladder Cancer: Current Multimodality Treatment Concepts and Future Directions.
Niklas Sturm, Jasmin Selina Schuhbaur, Felix Hüttner, Lukas Perkhofer, Thomas Jens Ettrich

November 2022

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Durvalumab in Advanced Biliary Tract Cancer: Real-World Data From a Large Cohort of Patients Across Multiple International Centers.
Margherita Rimini, Lorenzo Fornaro, Masafumi Ikeda, Oluseyi Abidoye, Jessica Lucchetti, Lukas Perkhofer

Liver Int· December 2025

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Negative impact of corticosteroid use on outcome in patients with advanced BTCs treated with cisplatin, gemcitabine, and durvalumab: A large real-life worldwide population.
Federica Lo Prinzi, Francesca Salani, Silvia Camera, Mario Domenico Rizzato, Anna Saborowski, Lukas Perkhofer

Int J Cancer· November 2025

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Genomic pathway alterations and their prognostic impact in biliary tract cancer: Insights from a multinational cohort treated with cisplatin, gemcitabine, and durvalumab.
Chiara Pirrone, Umberto Malapelle, Francesco Pepe, Federica Lo Prinzi, Federico Nichetti, Lukas Perkhofer

Eur J Cancer· November 2025

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GerPaCyst - The trial protocol of the prospective, multicenter, interdisciplinary German Pancreas Club Cyst Registry.
Kim Christin Honselmann, Jonathan Marschner, Anna Staufenbiel, Julia Bertram, Steffen Deichmann, Lukas Perkhofer

PLoS One· November 2025

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The impact of molecular alterations in patients with advanced biliary tract cancer receiving cisplatin, gemcitabine, and durvalumab: a large, real-life, worldwide population.
Margherita Rimini, Lorenzo Fornaro, Federica Lo Prinzi, Mario Domenico Rizzato, Anna Saborowski, Lukas Perkhofer

J Natl Cancer Inst· October 2025

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DKK3 Initially Preserves Acinar Integrity Through MEK-Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer.
Dharini Srinivasan, Elodie Roger, Lukas Perkhofer, Eleni Zimmer, Thomas F E Barth

Adv Sci (Weinh)· October 2025

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Factors associated with reaching maintenance therapy in patients with advanced biliary tract cancer treated with durvalumab: Real-world results from a multicenter and multinational study.
Margherita Rimini, Lorenzo Fornaro, Federica Lo Prinzi, Mario Domenico Rizzato, Anna Saborowski, Lukas Perkhofer

Int J Cancer· September 2025

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Homologous Repair-Deficient Pancreatic Cancer: Refined Targeting of DNA Damage Response is an Effective Therapeutic Strategy.
Alica K Beutel, Christopher J Halbrook, Menar Ekizce, Jessica Lindenmayer, Elodie Roger, Lukas Perkhofer

United European Gastroenterol J· September 2025

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Ivosidenib for IDH1-Mutant Intrahepatic Cholangiocarcinoma: Insights From a Multicenter Real-World Study.
Monica Niger, Margherita Rimini, Florian Castet, Anna Melzer, Mario Domenico Rizzato, Lukas Perkhofer

Liver Int· September 2025

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Impact of antibiotic therapy in patients with cholangiocarcinoma treated with chemoimmunotherapy.
Francesco Vitiello, Caterina Vivaldi, Mario Domenico Rizzato, Anna Saborowski, Lorenzo Antonuzzo, Lukas Perkhofer

Oncology· August 2025

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A Prognostic Index for Advanced Biliary Tract Cancer Treated With Cisplatin, Gemcitabine and Durvalumab: The MAGIC-D Index.
Mara Persano, Margherita Rimini, Francesca Salani, Federica Lo Prinzi, Federico Nichetti, Lukas Perkhofer

Liver Int· July 2025

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Unveiling the intriguing relationship: oncogenic KRAS, morphological shifts, and mutational complexity in pancreatic mucinous cystic neoplasms.
Lucas-Alexander Schulte, Annika Beck, Ralf Marienfeld, Ninel Azoitei, Thomas Fe Barth, Lukas Perkhofer

J Pathol· April 2025

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Efficacy of cisplatin-gemcitabine-durvalumab in patients with advanced biliary tract cancer experiencing early vs late disease relapse after surgery: a large real-life worldwide population.
Federica Lo Prinzi, Francesca Salani, Margherita Rimini, Mario Domenico Rizzato, Lorenzo Antonuzzo, Lukas Perkhofer

Oncologist· March 2025

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European guidelines for the diagnosis and treatment of pancreatic exocrine insufficiency: UEG, EPC, EDS, ESPEN, ESPGHAN, ESDO, and ESPCG evidence-based recommendations.
J Enrique Dominguez-Muñoz, Miroslav Vujasinovic, Daniel de la Iglesia, Djuna Cahen, Gabriele Capurso, Lukas Perkhofer

United European Gastroenterol J· February 2025

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Reply to Y. Liang et al.
Lukas Perkhofer, Thomas Seufferlein, Anna Melzer, Thomas J Ettrich

J Clin Oncol· January 2025

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Nanoliposomal Irinotecan With Fluorouracil and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Cholangiocarcinoma: A Phase II Study of the AIO Hepatobiliary-YMO Cancer Groups (NIFE-AIO-YMO HEP-0315).
Thomas J Ettrich, Dominik P Modest, Marianne Sinn, Jana K Striefler, Bernhard Opitz, Lukas Perkhofer

J Clin Oncol· September 2024

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Durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer: A large real-life worldwide population.
Margherita Rimini, Lorenzo Fornaro, Mario Domenico Rizzato, Lorenzo Antonuzzo, Federico Rossari, Lukas Perkhofer

Eur J Cancer· September 2024

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Prediction of resistance to bevacizumab plus FOLFOX in metastatic colorectal cancer-Results of the prospective multicenter PERMAD trial.
Thomas Seufferlein, Ludwig Lausser, Alexander Stein, Dirk Arnold, Gerald Prager, Lukas Perkhofer

PLoS One· June 2024

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SARS-Cov-2 vaccination is safe in autoimmune pancreatitis patients.
Lukas Perkhofer, Katja Kilani, Ägädius Wieser, Thomas Seufferlein, Pauline Kleger

United European Gastroenterol J· February 2024

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A Systematic Evaluation of the SARS-CoV-2 Vaccine-Induced Anti-S-RBD-Ig Response in a Population of Health Care Workers.
Viktoria Hentschel, Cornelia Horsch, Benjamin Mayer, Annsophie Thies, Will Qian, Lukas Perkhofer

Vaccines (Basel)· September 2023

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TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration.
Michael Karl Melzer, Silvia Schirge, Johann Gout, Frank Arnold, Dharini Srinivasan, Lukas Perkhofer

BMC Biol· March 2023

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Homologous recombination deficiency is inversely correlated with microsatellite instability and identifies immunologically cold tumors in most cancer types.
Jan Budczies, Klaus Kluck, Susanne Beck, Iordanis Ourailidis, Michael Allgäuer, Lukas Perkhofer

J Pathol Clin Res· July 2022

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A Methodological Workflow to Analyze Synthetic Lethality and Drug Synergism in Cancer Cells.
Johann Gout, Elodie Roger, Alexander Kleger, Lukas Perkhofer

Methods Mol Biol· July 2022

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Acute Reactions After Vaccination Against COVID-19 and Long-Term Antibody Levels.
Lukas Perkhofer, Jana Nägele, Joris Kroschel, Benjamin Mayer, Martin Müller

Dtsch Arztebl Int· July 2022

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