Publications by authors named "Luke Pilling"

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Predictors of MRI-estimated brain iron deposition in dementia and Parkinson's disease-associated subcortical regions: Genetic and observational analysis in UK Biobank.
Francesco Casanova, Qu Tian, Daniel S Williamson, Mitchell R Lucas, David Zweibaum, Luke C Pilling

J Alzheimers Dis· November 2025

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Proteogenomic signature of Alzheimer's disease and related dementia risk in individuals with major depressive disorder.
Breno Satler Diniz, Zhiduo Chen, David C Steffens, Luke Pilling, Yuliya Nikolova

Nat Ment Health· August 2025

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Understanding the causes and consequences of low statin adherence: evidence from UK Biobank primary care data.
Deniz Türkmen, Xiaoran Liang, Jane A H Masoli, Dipender Gill, Luke C Pilling

BMC Med· July 2025

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Plasma GDF15 affects long-term dementia risk and alters neuro-immune signaling.
Cassandra O Blew, Michael R Duggan, Dimitrios Tsitsipatis, Gabriela T Gomez, Zulema Rodriguez Hernandez, Luke C Pilling

medRxiv· July 2025

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A proteomic signature of healthspan.
Chia-Ling Kuo, Peiran Liu, Gabin Drouard, Eero Vuoksimaa, Jaakko Kaprio, Luke C Pilling

Proc Natl Acad Sci U S A· June 2025

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Incidence of liver complications with hemochromatosis-associated HFE p.C282Y homozygosity: The role of central adiposity.
Mitchell R Lucas, Luke C Pilling, Janice L Atkins, David Melzer

Hepatology· May 2025

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A proteomic signature of healthspan.
Chia-Ling Kuo, Peiran Liu, Gabin Drouard, Eero Vuoksimaa, Jaakko Kaprio, Luke C Pilling

medRxiv· March 2025

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A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data.
Olivia Murrin, Ninon Mounier, Bethany Voller, Linus Tata, Carlos Gallego-Moll, Luke C Pilling

EBioMedicine· March 2025

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Mitochondrial DNA copy number associated dementia risk by somatic mutations and frailty.
Qu Tian, David A Zweibaum, Yong Qian, Richard F Oppong, Luke C Pilling

Geroscience· February 2025

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Proteomic analysis of APOEε4 carriers implicates lipid metabolism, complement and lymphocyte signaling in cognitive resilience.
Keenan A Walker, Yang An, Abhay Moghekar, Ruin Moaddel, Michael R Duggan, Luke C Pilling

Mol Neurodegener· October 2024

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Proteogenomic signature of risk of Alzheimer's disease and related dementia risk in individuals with a history of major depression disorder.
Breno Satler Diniz, Zhiduo Chen, David C Steffens, Luke Pilling, Richard H Fortinsky

medRxiv· September 2024

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Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults.
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice L Atkins

Aging Cell· August 2024

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MRI-derived brain iron, grey matter volume, and risk of dementia and Parkinson's disease: Observational and genetic analysis in the UK Biobank cohort.
Francesco Casanova, Qu Tian, Daniel S Williamson, Yong Qian, David Zweibaum, Luke C Pilling

Neurobiol Dis· July 2024

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Is Mitochondrial DNA Copy Number from Human Blood Associated with Iron Deposits in the Brain?
Qu Tian, David A Zweibaum, Luke C Pilling, Francesco Casanova, Yong Qian

Antioxid Redox Signal· June 2024

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Iron and risk of dementia: Mendelian randomisation analysis in UK Biobank.
Francesco Casanova, Qu Tian, Janice L Atkins, Andrew R Wood, Daniel Williamson, Luke C Pilling

J Med Genet· April 2024

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Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults.
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice L Atkins

medRxiv· April 2024

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Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone.
Deniz Türkmen, Jack Bowden, Jane A H Masoli, João Delgado, Chia-Ling Kuo, Luke C Pilling

Pharmacogenomics J· April 2024

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Exome Sequencing and Statin Treatment Response in 64,000 UK Biobank Patients.
Deniz Türkmen, Jack Bowden, Jane A H Masoli, David Melzer, Luke C Pilling

Int J Mol Sci· April 2024

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genotypes, haemochromatosis diagnosis and clinical outcomes at age 80 years: a prospective cohort study in the UK Biobank.
Mitchell R Lucas, Janice L Atkins, Luke C Pilling, Jeremy D Shearman, David Melzer

BMJ Open· March 2024

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Does physical activity moderate the association between shorter leukocyte telomere length and incident coronary heart disease? Data from 54,180 UK Biobank participants.
Meiruo Xiang, Luke C Pilling, David Melzer, Ben Kirk, Gustavo Duque

Geroscience· February 2024

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Hemochromatosis Genetic Variants and Musculoskeletal Outcomes: 11.5-Year Follow-Up in the UK Biobank Cohort Study.
Lucy R Banfield, Karen M Knapp, Luke C Pilling, David Melzer, Janice L Atkins

JBMR Plus· October 2023

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Mid-life leukocyte telomere length and dementia risk: An observational and mendelian randomization study of 435,046 UK Biobank participants.
Rui Liu, Meiruo Xiang, Luke C Pilling, David Melzer, Lihong Wang

Aging Cell· July 2023

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Association between Residential Exposure to Air Pollution and Incident Coronary Heart Disease Is Not Mediated by Leukocyte Telomere Length: A UK Biobank Study.
Chia-Ling Kuo, Rui Liu, Lucas da Cunha Godoy, Luke C Pilling, Richard H Fortinsky

Toxics· May 2023

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Letter to the editor regarding: "A haemochromatosis-causing HFE mutation is associated with SARS-CoV-2 susceptibility in the Czech population" clinica chimica acta 538 (2023) 211-215.
Janice L Atkins, Mitchell R Lucas, Luke C Pilling, David Melzer

Clin Chim Acta· March 2023

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Very Low and High Levels of Vitamin D Are Associated with Shorter Leukocyte Telomere Length in 148,321 UK Biobank Participants.
Chia-Ling Kuo, Ben Kirk, Meiruo Xiang, Luke C Pilling, George A Kuchel

Nutrients· March 2023

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