Publications by authors named "Luned Badder"

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OSCAR is an online ML-powered tool for organoid cell counting using bright-field images.
Stephanie E A Burnell, Lorenzo Capitani, Chloe A Harris, Luned M Badder, Alan L Parker

Cell Rep Methods· December 2025

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An αvβ6-specific virotherapy expressing bispecific immune cell activators induces immune cell activation to mediate tumor cell death.
Rebecca J Bayliss, Luned M Badder, James Davies, Andrew Robinson, Mona Pissarreck

Mol Ther Oncol· September 2025

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The αvβ6 integrin specific virotherapy, Ad5-A20.FCU1, selectively delivers potent "in-tumour" chemotherapy to pancreatic ductal adenocarcinoma.
Luned M Badder, James A Davies, Valerie S Meniel, Mahulena Marušková, Beatriz Salvador-Barbero

Br J Cancer· November 2024

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A pseudotyped adenovirus serotype 5 vector with serotype 49 fiber knob is an effective vector for vaccine and gene therapy applications.
Carly M Bliss, Sarah L Hulin-Curtis, Marta Williams, Mahulena Marušková, James A Davies, Luned M Badder

Mol Ther Methods Clin Dev· September 2024

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The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.
Dragomir B Krastev, Shudong Li, Yilun Sun, Andrew J Wicks, Gwendoline Hoslett, Luned M Badder

Nat Cell Biol· January 2022

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Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.
Diana Zatreanu, Helen M R Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Luned M Badder

Nat Commun· June 2021

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Efficient Intravenous Tumor Targeting Using the αvβ6 Integrin-Selective Precision Virotherapy Ad5-A20.
James A Davies, Gareth Marlow, Hanni K Uusi-Kerttula, Gillian Seaton, Luke Piggott, Luned M Badder

Viruses· May 2021

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3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.
Luned M Badder, Andrew J Hollins, Bram Herpers, Kuan Yan, Kenneth B Ewan, Delyth A Badder

PLoS One· September 2020

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Insights into pancreatic β cell energy metabolism using rodent β cell models.
Karl J Morten, Michelle Potter, Luned Badder, Pamela Sivathondan, Rebecca Dragovic

Wellcome Open Res· September 2019

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Anti-Folate Receptor Alpha-Directed Antibody Therapies Restrict the Growth of Triple-negative Breast Cancer.
Anthony Cheung, James Opzoomer, Kristina M Ilieva, Patrycja Gazinska, Ricarda M Hoffmann, Luned Badder

Clin Cancer Res· October 2018

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Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA.
Paul J Kemp, David J Rushton, Polina L Yarova, Christian Schnell, Charlene Geater, Luned Badder

J Physiol· November 2016

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Monitoring Intracellular Oxygen Concentration: Implications for Hypoxia Studies and Real-Time Oxygen Monitoring.
Michelle Potter, Luned Badder, Yvette Hoade, Iain G Johnston, Karl J Morten

Adv Exp Med Biol· May 2016

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Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons.
Vsevolod Telezhkin, Christian Schnell, Polina Yarova, Sun Yung, Emma Cope, Luned Badder

Am J Physiol Cell Physiol· April 2016

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Differential regulation of HIF-mediated pathways increases mitochondrial metabolism and ATP production in hypoxic osteoclasts.
Karl J Morten, Luned Badder, Helen J Knowles

J Pathol· April 2013

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