Publications by authors named "Lutz Preu"

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Evaluation of Ruthenium(II) -Heterocyclic Carbene Complexes as Antibacterial Agents and Inhibitors of Bacterial Thioredoxin Reductase.
Hilke Burmeister, Pascal Dietze, Lutz Preu, Julia E Bandow, Ingo Ott

Molecules· July 2021

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A promiscuous coenzyme A ligase provides benzoyl-coenzyme A for xanthone biosynthesis in Hypericum.
Poonam Singh, Lutz Preu, Till Beuerle, David Kaufholdt, Robert Hänsch

Plant J· December 2020

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[]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors.
Christian Lechner, Maren Flaßhoff, Hannes Falke, Lutz Preu, Nadége Loaëc

Molecules· November 2019

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Structure-activity relationships in a series of antiplasmodial thieno[2,3-b]pyridines.
Andreas Masch, Abed Nasereddin, Arne Alder, Megan J Bird, Sandra I Schweda, Lutz Preu

Malar J· March 2019

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Molecular structures of cdc2-like kinases in complex with a new inhibitor chemotype.
Anne Walter, Apirat Chaikuad, Renate Helmer, Nadège Loaëc, Lutz Preu

PLoS One· August 2018

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Scaffold hopping identifies 6,8-disubstituted purines as novel anaplastic lymphoma kinase inhibitors.
Laura Schlütke, Markus Immer, Lutz Preu, Frank Totzke, Christoph Schächtele

Eur J Pharm Biopharm· May 2018

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Indole-3-Carbonitriles as DYRK1A Inhibitors by Fragment-Based Drug Design.
Rosanna Meine, Walter Becker, Hannes Falke, Lutz Preu, Nadège Loaëc

Molecules· January 2018

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Metal ion - Dehydrin interactions investigated by affinity capillary electrophoresis and computer models.
Markus Nachbar, Mona Mozafari, Friederike Krull, Kai-Jorrit Maul, Lutz Preu

J Plant Physiol· September 2017

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Using affinity capillary electrophoresis and computational models for binding studies of heparinoids with p-selectin and other proteins.
Mona Mozafari, Shantheya Balasupramaniam, Lutz Preu, Sami El Deeb, Christian G Reiter

Electrophoresis· June 2017

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Antiplasmodial dihetarylthioethers target the coenzyme A synthesis pathway in Plasmodium falciparum erythrocytic stages.
Thomas Weidner, Leonardo Lucantoni, Abed Nasereddin, Lutz Preu, Peter G Jones

Malar J· May 2017

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Identification of CLK1 Inhibitors by a Fragment-linking Based Virtual Screening.
Anne Walter, Apirat Chaikuad, Nadège Loaëc, Lutz Preu, Stefan Knapp

Mol Inform· April 2017

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5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms.
Oliver C F Orban, Ricarda S Korn, Diego Benítez, Andrea Medeiros, Lutz Preu

Bioorg Med Chem· August 2016

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Ca(2+) -complex stability of GAPAGPLIVPY peptide in gas and aqueous phase, investigated by affinity capillary electrophoresis and molecular dynamics simulations and compared to mass spectrometric results.
Markus Nachbar, Sami El Deeb, Mona Mozafari, Hassan A Alhazmi, Lutz Preu

Electrophoresis· March 2016

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Novel 2-Phenoxyanilide Congeners Derived from a Hit Structure of the TCAMS: Synthesis and Evaluation of Their in Vitro Activity against Plasmodium falciparum.
Thomas Weidner, Abed Nasereddin, Lutz Preu, Johann Grünefeld, Ron Dzikowski

Molecules· February 2016

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10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A.
Hannes Falke, Apirat Chaikuad, Anja Becker, Nadège Loaëc, Olivier Lozach, Lutz Preu

J Med Chem· April 2015

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Precise, fast, and flexible determination of protein interactions by affinity capillary electrophoresis: part 3: anions.
Yuanhong Xu, Sabine Redweik, Deia Abd El-Hady, Hassan M Albishri, Lutz Preu

Electrophoresis· August 2014

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9- and 11-Substituted 4-azapaullones are potent and selective inhibitors of African trypanosoma.
Franziska Maiwald, Diego Benítez, Diego Charquero, Mahin Abad Dar, Hanna Erdmann, Lutz Preu

Eur J Med Chem· August 2014

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Parenteral formulation of an antileishmanial drug candidate--tackling poor solubility, chemical instability, and polymorphism.
Eva Kupetz, Lutz Preu, Conrad Kunick, Heike Bunjes

Eur J Pharm Biopharm· November 2013

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2-Arylpaullones are selective antitrypanosomal agents.
Jasmin Ryczak, Ma'ayan Papini, Annette Lader, Abedelmajeed Nasereddin, Dmitry Kopelyanskiy, Lutz Preu

Eur J Med Chem· June 2013

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3,6-Diamino-4-(2-halophenyl)-2-benzoylthieno[2,3-b]pyridine-5-carbonitriles are selective inhibitors of Plasmodium falciparum glycogen synthase kinase-3.
Wiebke Fugel, Anselm Erich Oberholzer, Bernhard Gschloessl, Ron Dzikowski, Narkiss Pressburger, Lutz Preu

J Med Chem· January 2013

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2-Anilino-4-(benzimidazol-2-yl)pyrimidines--a multikinase inhibitor scaffold with antiproliferative activity toward cancer cell lines.
Renate Determann, Jan Dreher, Knut Baumann, Lutz Preu, Peter G Jones

Eur J Med Chem· July 2012

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Dual IGF-1R/SRC inhibitors based on a N'-aroyl-2-(1H-indol-3-yl)-2-oxoacetohydrazide structure.
Stefanie Schmidt, Lutz Preu, Thomas Lemcke, Frank Totzke, Christoph Schächtele

Eur J Med Chem· July 2011

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Inhibitors of the RET tyrosine kinase based on a 2-(alkylsulfanyl)-4-(3-thienyl)nicotinonitrile scaffold.
Wiebke Brandt, Luca Mologni, Lutz Preu, Thomas Lemcke, Carlo Gambacorti-Passerini

Eur J Med Chem· July 2010

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Identification of 2-anilino-9-methoxy-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-ones as dual PLK1/VEGF-R2 kinase inhibitor chemotypes by structure-based lead generation.
Anne-Marie Egert-Schmidt, Jan Dreher, Ute Dunkel, Simone Kohfeld, Lutz Preu

J Med Chem· March 2010

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Development of 5-benzylpaullones and paullone-9-carboxylic acid alkyl esters as selective inhibitors of mitochondrial malate dehydrogenase (mMDH).
Anja Becker, Simone Kohfeld, Annette Lader, Lutz Preu, Tanja Pies

Eur J Med Chem· January 2010

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