Publications by authors named "Ly Ngo"

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Long-term efficacy and safety of perampanel in patients aged 60 years and older with focal seizures: Post hoc analysis of phase III open-label extension studies stratified by enzyme-inducing anti-seizure medication use.
Rohit Marawar, Ilo E Leppik, Robert T Wechsler, Anna Patten, Leock Y Ngo

Epilepsy Behav Rep· December 2025

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Efficacy and safety of perampanel as first adjunctive therapy in patients with focal-onset seizures or generalized tonic-clonic seizures in four post-marketing studies across regions.
Stefano Meletti, Vineet Punia, Amitabh Dash, Anna Lisa Gentile, Ricardo Sáinz-Fuertes, Leock Y Ngo

Epilepsia Open· November 2025

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Time to prerandomization seizure count design sufficiently assessed the safety and tolerability of perampanel for the treatment of focal seizures.
Wesley T Kerr, Leock Y Ngo, Liang Zhu, Anna Patten, Jocelyn Y Cheng

Epilepsia· September 2025

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Safety, Tolerability, and Pharmacokinetics of NRL-1049, a Rho-Associated Kinase Inhibitor, in Healthy Volunteers: A Phase 1, First-in-Human, Single-Ascending Dose, Randomized, Placebo-Controlled Trial.
Stuart Madden, Issam Awad, Miguel A Lopez-Toledano, Leslie Morrison, Juan Gutierrez, Leock Y Ngo

CNS Drugs· September 2025

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Pharmacokinetics and 180-day safety of diazepam nasal spray in pediatric patients with epilepsy aged 2-5 years.
Eric B Segal, James W Wheless, Muhammad Zafar, Evelyn K Shih, Leock Y Ngo

Epilepsia· September 2025

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Potential for Therapeutic Alteration of the Underlying Biology of Epilepsy.
Michael R Sperling, Jurriaan M Peters, Qian Wu, Michelle Guignet, H Steve White, Leock Y Ngo

Biomedicines· September 2025

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Real-world use of adjunctive perampanel for focal-onset seizures in Italy: A mirroring clinical practice study of perampanel in adults and adolescents (AMPA).
Alfredo D'Aniello, Anna Teresa Giallonardo, Paolo Tinuper, Oriano Mecarelli, Umberto Aguglia, Leock Y Ngo

Epilepsia Open· August 2025

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Long-term safety and efficacy of adjunctive perampanel in pediatric patients (ages 4 to <12 years) with inadequately controlled focal-onset seizures or generalized tonic-clonic seizures.
Robert Flamini, Andras Fogarasi, Hirowo Omatsu, Mathieu Milh, Steven Phillips, Leock Y Ngo

Epilepsia· April 2025

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Efficacy and safety of perampanel in patients with seizures associated with Lennox-Gastaut syndrome: A randomized trial.
David G Vossler, Brenda E Porter, Ryutaro Kira, Jeehun Lee, Alec Aeby, Leock Y Ngo

Epilepsia· February 2025

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Time to prerandomization seizure count design sufficiently assessed the safety and tolerability of perampanel for the treatment of primary generalized tonic-clonic seizures.
Wesley T Kerr, Leock Y Ngo, Liang Zhu, Anna Patten, Jocelyn Y Cheng

Epilepsia· August 2024

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Perampanel as monotherapy or first adjunctive therapy in pediatric and adult patients with epilepsy: the first United States-based phase IV open-label ELEVATE study.
Vineet Punia, Pavel Klein, Temenuzhka Mihaylova, Victor Biton, Omar Samad, Leock Y Ngo

J Neurol· July 2024

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Intravenous perampanel as an alternative to the oral formulations in Japanese patients with epilepsy.
Ryosuke Hanaya, Yuichi Kubota, Masahiro Mizobuchi, Koji Iida, Tomonori Ono, Leock Y Ngo

Epilepsia Open· December 2023

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Open-label study to investigate the safety and efficacy of adjunctive perampanel in pediatric patients (aged 4 to <12 years) with inadequately controlled focal-onset seizures: Japanese subgroup analysis.
Hirowo Omatsu, Toshihide Watanabe, Ryutaro Kira, Kaeko Ishiba, Anna Patten, Leock Y Ngo

Seizure· August 2023

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Determination of drug-related problems among type 2 diabetes outpatients in a hospital in Vietnam: A cross-sectional study.
Duong Thi Ly Huong, Nguyen Thanh Hang, Nguyen Khanh Ly, Nguyen Hong Nhat, Nguyen Thi Lan Huong, Nguyen Ngoc Hieu, Ngo Hai Ly

PLoS One· August 2023

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Translating and Validating the Vietnamese Version of the Health Sciences Evidence-Based Practice Questionnaire.
Quyen Thao Nguyen, Mei-Ling Yeh, Ly Thi Hai Ngo, Chiehfeng Chen

Int J Environ Res Public Health· March 2023

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Time to exceed pre-randomization monthly seizure count for perampanel in participants with primary generalized tonic-clonic seizures: A potential clinical end point.
Wesley T Kerr, Christian Brandt, Leock Y Ngo, Anna Patten, Jocelyn Y Cheng

Epilepsia· November 2022

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Intravenous Perampanel as an Interchangeable Alternative to Oral Perampanel: A Randomized, Crossover, Phase I Pharmacokinetic and Safety Study.
Ziad Hussein, Oneeb Majid, Peter Boyd, Jagadeesh Aluri, Leock Y Ngo

Clin Pharmacol Drug Dev· July 2022

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Experience of perampanel monotherapy beyond initial titration to achieve seizure freedom in patients with focal-onset seizures with newly diagnosed or currently untreated recurrent epilepsy: A post hoc analysis of the open-label Study 342 (FREEDOM).
Ryan Edbert Husni, Leock Y Ngo, Hirofumi Senokuchi, Anna Patten, Hidetaka Hiramatsu

Epilepsia Open· March 2022

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Sustained seizure freedom with adjunctive perampanel in patients with convulsive seizures: Post hoc analysis of open-label extension studies 307 and 332.
Trevor Resnick, Anna Patten, Leock Y Ngo, Manoj Malhotra

Epilepsy Behav· March 2022

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A post-approval observational study to evaluate the safety and tolerability of perampanel as an add-on therapy in adolescent, adult, and elderly patients with epilepsy.
Melissa Maguire, Elinor Ben-Menachem, Anna Patten, Manoj Malhotra, Leock Y Ngo

Epilepsy Behav· January 2022

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Health-related quality of life in pediatric patients with partial onset seizures or primary generalized tonic-clonic seizures receiving adjunctive perampanel.
Andrew Trigg, Elaine Brohan, Kim Cocks, Amy Jones, Amir A Tahami Monfared, Leock Y Ngo

Epilepsy Behav· May 2021

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Adjunctive perampanel and myoclonic and absence seizures: Post hoc analysis of data from study 332 in patients with idiopathic generalized epilepsy.
Christian Brandt, Robert T Wechsler, Terence J O'Brien, Anna Patten, Manoj Malhotra, Leock Y Ngo

Seizure· August 2020

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Influence of External NaCl Salt on Membrane Rigidity of Neutral DOPC Vesicles.
Judith U De Mel, Sudipta Gupta, Rasangi M Perera, Ly Ngo, Piotr Zolnierczuk

Langmuir· August 2020

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A large multicentre, randomized, double-blind, cross-over study in healthy volunteers to compare pharmacokinetics, pharmacodynamics and safety of a pegfilgrastim biosimilar with its US- and EU-reference biologics.
Anne Bellon, Jessie Wang, Andrej Skerjanec, Maria Velinova, Daniel Dickerson, Ly Ngo

Br J Clin Pharmacol· June 2020

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Open-label study to investigate the safety and efficacy of adjunctive perampanel in pediatric patients (4 to <12 years) with inadequately controlled focal seizures or generalized tonic-clonic seizures.
Andras Fogarasi, Robert Flamini, Mathieu Milh, Steven Phillips, Shinsaku Yoshitomi, Leock Y Ngo

Epilepsia· January 2020

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