Publications by authors named "Lyle D Burgoon"

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Octamethylcyclotetrasiloxane (D4) lacks endocrine disruptive potential via estrogen pathways.
Christopher J Borgert, Lyle D Burgoon

Arch Toxicol· April 2025

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Challenges and Opportunities in the Development and Adoption of New Approach Methods (NAMs).
Steven L Levine, Leah S Riter, Laurent Lagadic, Adriana C Bejarano, Natalie Burden, Lyle D Burgoon

J Agric Food Chem· April 2025

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Kinetically-derived maximal dose (KMD) confirms lack of human relevance for high-dose effects of octamethylcyclotetrasiloxane (D4).
Christopher J Borgert, Lyle D Burgoon, Claudio Fuentes

Arch Toxicol· February 2025

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The database makes the poison: How the selection of datasets in QSAR models impacts toxicant prediction of higher tier endpoints.
Lyle D Burgoon, Felix M Kluxen, Anja Hüser, Markus Frericks

Regul Toxicol Pharmacol· August 2024

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The physiological and biochemical basis of potency thresholds modeled using human estrogen receptor alpha: implications for identifying endocrine disruptors.
Christopher J Borgert, Lyle D Burgoon, John C Matthews

Arch Toxicol· June 2024

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Kinetically-derived maximal dose (KMD) indicates lack of human carcinogenicity of ethylbenzene.
Lyle D Burgoon, Christopher J Borgert, Claudio Fuentes, James E Klaunig

Arch Toxicol· January 2024

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Range of the perfluorooctanoate (PFOA) safe dose for human health: An international collaboration.
Lyle D Burgoon, Harvey J Clewell, Tony Cox, Wolfgang Dekant, Linda D Dell

Regul Toxicol Pharmacol· December 2023

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Understanding and overcoming the technical challenges in using in silico predictions in regulatory decisions of complex toxicological endpoints - A pesticide perspective for regulatory toxicologists with a focus on machine learning models.
Lyle D Burgoon, Felix M Kluxen, Markus Frericks

Regul Toxicol Pharmacol· January 2023

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Comment on "Application of an Assay to Identify Chemicals That Increase Estradiol and Progesterone Synthesis and Are Potential Breast Cancer Risk Factors".
Lyle D Burgoon, Christopher J Borgert

Environ Health Perspect· May 2022

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A novel approach to calculating the kinetically derived maximum dose.
Lyle D Burgoon, Claudio Fuentes, Christopher J Borgert

Arch Toxicol· March 2022

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Organizing mechanism-related information on chemical interactions using a framework based on the aggregate exposure and adverse outcome pathways.
Paul S Price, Annie M Jarabek, Lyle D Burgoon

Environ Int· May 2020

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Predicting the Probability that a Chemical Causes Steatosis Using Adverse Outcome Pathway Bayesian Networks (AOPBNs).
Lyle D Burgoon, Michelle Angrish, Natalia Garcia-Reyero, Nathan Pollesch, Anze Zupanic

Risk Anal· March 2020

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Different as night and day: Behavioural and life history responses to varied photoperiods in Daphnia magna.
Kurt A Gust, Alan J Kennedy, Jennifer G Laird, Mitchell S Wilbanks, Natalie D Barker, Lyle D Burgoon

Mol Ecol· October 2019

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Introducing WikiPathways as a Data-Source to Support Adverse Outcome Pathways for Regulatory Risk Assessment of Chemicals and Nanomaterials.
Marvin Martens, Tim Verbruggen, Penny Nymark, Roland Grafström, Lyle D Burgoon

Front Genet· December 2018

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Using In Vitro High-Throughput Screening Data for Predicting Benzo[k]Fluoranthene Human Health Hazards.
Lyle D Burgoon, Ingrid L Druwe, Kyle Painter, Erin E Yost

Risk Anal· February 2017

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A decision analysis framework for estimating the potential hazards for drinking water resources of chemicals used in hydraulic fracturing fluids.
Erin E Yost, John Stanek, Lyle D Burgoon

Sci Total Environ· January 2017

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Response to Cohen et al. (2016) regarding response to Druwe and Burgoon.
Ingrid L Druwe, Lyle D Burgoon

Arch Toxicol· December 2016

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The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions.
Ila Cote, Melvin E Andersen, Gerald T Ankley, Stanley Barone, Linda S Birnbaum, Lyle D Burgoon

Environ Health Perspect· November 2016

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Estimating the Potential Toxicity of Chemicals Associated with Hydraulic Fracturing Operations Using Quantitative Structure-Activity Relationship Modeling.
Erin E Yost, John Stanek, Robert S DeWoskin, Lyle D Burgoon

Environ Sci Technol· July 2016

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Loss of Hif-2α Rescues the Hif-1α Deletion Phenotype of Neonatal Respiratory Distress In Mice.
Yogesh Saini, Steven P Proper, Peter Dornbos, Krista K Greenwood, Anna K Kopec, Lyle D Burgoon

PLoS One· June 2016

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A Market-Basket Approach to Predict the Acute Aquatic Toxicity of Munitions and Energetic Materials.
Lyle D Burgoon

Bull Environ Contam Toxicol· June 2016

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Overview of Chronic Oral Toxicity Values for Chemicals Present in Hydraulic Fracturing Fluids, Flowback, and Produced Waters.
Erin E Yost, John Stanek, Robert S DeWoskin, Lyle D Burgoon

Environ Sci Technol· May 2016

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Can data science inform environmental justice and community risk screening for type 2 diabetes?
J Allen Davis, Lyle D Burgoon

PLoS One· April 2016

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Systematic Omics Analysis Review (SOAR) tool to support risk assessment.
Emma R McConnell, Shannon M Bell, Ila Cote, Rong-Lin Wang, Edward J Perkins, Lyle D Burgoon

PLoS One· August 2015

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A framework for the next generation of risk science.
Daniel Krewski, Margit Westphal, Melvin E Andersen, Gregory M Paoli, Weihsueh A Chiu, Lyle D Burgoon

Environ Health Perspect· August 2014

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