Publications by authors named "Lynee Massey"

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Autophagy activator AA-20 improves proteostasis and extends lifespan.
Ee Phie Tan, Nora Lyang, Saam Doroodian, Pablo Sanz-Martinez, Jin Xu, Lynée A Massey

Proc Natl Acad Sci U S A· August 2025

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Autophagy activators normalize aberrant Tau proteostasis and rescue synapses in human familial Alzheimer's disease iPSC-derived cortical organoids.
Sergio R Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Lynee Massey

bioRxiv· July 2025

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A PIKfyve modulator combined with an integrated stress response inhibitor to treat lysosomal storage diseases.
William C Hou, Lynée A Massey, Derek Rhoades, Yin Wu, Wen Ren

Proc Natl Acad Sci U S A· August 2024

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Unified Synthesis of 2-Isocyanoallopupukeanane and 9-Isocyanopupukeanane through a "Contra-biosynthetic" Rearrangement.
Melissa A Hardy, Jack Hayward Cooke, Zhitao Feng, Kenta Noda, Isabel Kerschgens, Lynée A Massey

Angew Chem Int Ed Engl· January 2024

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A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway.
Suzanne Elsasser, Lisa P Elia, Richard I Morimoto, Evan T Powers, Daniel Finley, Lynée A Massey

bioRxiv· March 2023

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Synthesis of Chiral Tetrasubstituted Azetidines from Donor-Acceptor Azetines via Asymmetric Copper(I)-Catalyzed Imido-Ylide [3+1]-Cycloaddition with Metallo-Enolcarbenes.
Kostiantyn O Marichev, Kan Wang, Kuiyong Dong, Nicole Greco, Lynée A Massey

Angew Chem Int Ed Engl· November 2019

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Chiral donor-acceptor azetines as powerful reactants for synthesis of amino acid derivatives.
Kostiantyn O Marichev, Kuiyong Dong, Lynée A Massey, Yongming Deng, Luca De Angelis

Nat Commun· November 2019

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Copper-Catalyzed Formal [4+2] Cycloaddition of Enoldiazoimides with Sulfur Ylides.
Qing-Qing Cheng, Lynée A Massey, Brook S Willett, Yongming Deng, Hadi Arman

Angew Chem Int Ed Engl· August 2018

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Catalytic Divergent [3+3]- and [3+2]-Cycloaddition by Discrimination Between Diazo Compounds.
Yongming Deng, Lynée A Massey, Yeray A Rodriguez Núñez, Hadi Arman, Michael P Doyle

Angew Chem Int Ed Engl· September 2017

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Catalytic Asymmetric [3+1]-Cycloaddition Reaction of Ylides with Electrophilic Metallo-enolcarbene Intermediates.
Yongming Deng, Lynée A Massey, Peter Y Zavalij, Michael P Doyle

Angew Chem Int Ed Engl· June 2017

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