Publications by authors named "Magnus Hoffmann"

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Recruiting ESCRT to single-chain heterotrimer peptide MHCI releases antigen-presenting vesicles that stimulate T cells selectively.
Blade A Olson, Kathryn E Huey-Tubman, Zhiyuan Mao, Magnus A G Hoffmann, Pamela J Bjorkman

Proc Natl Acad Sci U S A· December 2025

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mRNA delivery of genetically encoded mosaic-8 pan-sarbecovirus RBD vaccines.
Alexander A Cohen, Jennifer R Keeffe, Lusineh Manasyan, Indeever Madireddy, Ange-Célia I Priso Fils, Magnus A G Hoffmann

bioRxiv· October 2025

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Bivalent mRNA booster encoding virus-like particles elicits potent polyclass RBD antibodies in pre-vaccinated mice.
Chengcheng Fan, Alexander A Cohen, Kim-Marie A Dam, Annie V Rorick, Ange-Célia I Priso Fils, Magnus A G Hoffmann

bioRxiv· August 2025

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The Interplay of Furin Cleavage and D614G in Modulating SARS-CoV-2 Spike Protein Dynamics.
Sophie R Shoemaker, Megan Luo, Kim-Marie A Dam, John E Pak, Magnus A G Hoffmann

bioRxiv· January 2025

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ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines.
Magnus A G Hoffmann, Zhi Yang, Kathryn E Huey-Tubman, Alexander A Cohen, Priyanthi N P Gnanapragasam

Cell· May 2023

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CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals.
Harry B Gristick, Harald Hartweger, Maximilian Loewe, Jelle van Schooten, Victor Ramos, Magnus A G Hoffmann

Sci Immunol· February 2023

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ESCRT recruitment to mRNA-encoded SARS-CoV-2 spike induces virus-like particles and enhanced antibody responses.
Magnus A G Hoffmann, Zhi Yang, Kathryn E Huey-Tubman, Alexander A Cohen, Priyanthi N P Gnanapragasam

bioRxiv· December 2022

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Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Zhi Yang, Kim-Marie A Dam, Michael D Bridges, Magnus A G Hoffmann, Andrew T DeLaitsch

Nat Commun· February 2022

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Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env.
Amelia Escolano, Harry B Gristick, Rajeev Gautam, Andrew T DeLaitsch, Morgan E Abernathy, Magnus A G Hoffmann

Sci Transl Med· November 2021

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characterization of engineered red blood cells as viral traps against HIV-1 and SARS-CoV-2.
Magnus A G Hoffmann, Collin Kieffer, Pamela J Bjorkman

Mol Ther Methods Clin Dev· June 2021

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Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Christopher O Barnes, Anthony P West, Kathryn E Huey-Tubman, Magnus A G Hoffmann, Naima G Sharaf

Cell· August 2020

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Nanoparticles presenting clusters of CD4 expose a universal vulnerability of HIV-1 by mimicking target cells.
Magnus A G Hoffmann, Yotam Bar-On, Zhi Yang, Harry B Gristick, Priyanthi N P Gnanapragasam

Proc Natl Acad Sci U S A· August 2020

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Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies.
Christopher O Barnes, Anthony P West, Kathryn E Huey-Tubman, Magnus A G Hoffmann, Naima G Sharaf

bioRxiv· May 2020

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Enhanced broadband fluorescence detection of nucleic acids using multipolar gap-plasmons on biomimetic Au metasurfaces.
Vinayak Narasimhan, Radwanul Hasan Siddique, Magnus Hoffmann, Shailabh Kumar, Hyuck Choo

Nanoscale· August 2019

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Investigation into process-induced de-aggregation of cohesive micronised API particles.
Magnus Hoffmann, Patrick S Wray, John F Gamble, Mike Tobyn

Int J Pharm· September 2015

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Monitoring process induced attrition of drug substance particles within formulated blends.
John F Gamble, Magnus Hoffmann, Helen Hughes, Paul Hutchins, Mike Tobyn

Int J Pharm· August 2014

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