Publications by authors named "Mandy Chan"

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Adipocyte-derived FABP4 promotes metabolism-associated steatotic liver-induced hepatocellular carcinoma by driving ITGB1-mediated β-catenin activation.
Carmen Oi Ning Leung, Shilpa Gurung, Katherine Po Sin Chung, Rainbow Wing Hei Leung, Martina Mang Leng Lei, Mandy Sze Man Chan

J Clin Invest· December 2025

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Non-invasive risk-based surveillance of hepatocellular carcinoma in patients with metabolic dysfunction-associated steatotic liver disease.
Jimmy Che-To Lai, Boyu Yang, Hye Won Lee, Huapeng Lin, Emmanuel A Tsochatzis, Wah-Kheong Chan, Mandy Sau-Wai Chan

Gut· November 2025

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Histological severity and hepatic outcomes in patients with MASLD and discrepant FIB-4 and liver stiffness measurement.
Joseph Rabbat, Boyu Yang, Hye Won Lee, Huapeng Lin, Emmanuel Tsochatzis, Wah-Kheong Chan, Mandy Sau-Wai Chan

Clin Mol Hepatol· November 2025

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Wild-type KRAS activation drives evasion of interferon-mediated immunity and resistance to immunotherapy in hepatocellular carcinoma.
Martina Mang Leng Lei, Carmen Oi Ning Leung, Rainbow Wing Hei Leung, Xue Qian Wu, Katherine Po Sin Chung, Mandy Sze Man Chan, Stephen Lam Chan

Nat Commun· November 2025

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Human Single-Nucleus RNA Sequencing Identifies CD47 as a Therapeutic Target for Doxorubicin-Induced Cardiomyopathy.
Zhen Guo, Anahita Ataran, Pan Ma, Wenjing Yu, Hamidreza Hajirezaei, Mandy M Chan, Kodi S Ravichandran

Circulation· September 2025

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Prognostic performance of the two-step clinical care pathway in metabolic dysfunction-associated steatotic liver disease.
Terry Cheuk-Fung Yip, Hye Won Lee, Huapeng Lin, Emmanuel Tsochatzis, Salvatore Petta, Wah-Kheong Chan, Mandy Sau-Wai Chan

J Hepatol· August 2025

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From "Burnt-Out" to "Burning-Out": Capturing Liver Fat Loss in Patients With Advanced Metabolic Dysfunction-Associated Steatotic Liver Disease From a Dynamic Perspective.
Wen-Yue Liu, Shanshan Huang, Hongsheng Ji, Seung Up Kim, Terry Cheuk-Fung Yip, Wah-Kheong Chan, Mandy Sau-Wai Chan

Gastroenterology· August 2025

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Effect of hypertension on long-term adverse clinical outcomes and liver fibrosis progression in MASLD.
Xiao-Dong Zhou, Li-You Lian, Qin-Fen Chen, Seung Up Kim, Terry Cheuk-Fung Yip, Wah-Kheong Chan, Mandy Sau-Wai Chan

J Hepatol· August 2025

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A Critical Role for the Mitochondrial Pyruvate Carrier in Hepatic Stellate Cell Activation.
Mohammad Habibi, Daniel Ferguson, Sophie J Eichler, Mandy M Chan, Christina Fu

Cell Mol Gastroenterol Hepatol· July 2025

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Oncogenic Activity and Sorafenib Sensitivity of p.S214C Mutation in Lung Cancer.
Carol Lee, Weixue Mu, Xi July Chen, Mandy Sze Man Chan, Zhishan Chen, Helen Hoi Yin Chan, David Wai Chan

Cancers (Basel)· July 2025

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Effect of Antidiabetic Drug Classes on the Risk of Liver-Related Events in Individuals With T2D and MASLD.
Yu Shi, Seung Up Kim, Terry Cheuk-Fung Yip, Emmanuel Tsochatzis, Salvatore Petta, Wah-Kheong Chan, Mandy Sau-Wai Chan

Clin Gastroenterol Hepatol· June 2025

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acFibroMASH Index for the Diagnosis of Fibrotic MASH and Prediction of Liver-related Events: An International Multicenter Study.
Gong Feng, Ferenc E Mózes, Dong Ji, Sombat Treeprasertsuk, Takeshi Okanoue, Wah Kheong Chan, Mandy Sau-Wai Chan

Clin Gastroenterol Hepatol· April 2025

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Biliary Metaplasia and Macrophage Activation Define the Cellular Landscape of Cardiogenic Liver Disease.
Arick C Park, Christina F Fu, Adeesh Parvathaneni, Bin Q Yang, Mandy M Chan

JACC Basic Transl Sci· April 2025

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Development of an improved construct for spectinomycin selection in plant transformation.
Kent F McCue, Min Shao, Jennie Huynh, Tai Minh, Mandy Chan

BMC Res Notes· March 2025

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Tracing LYVE1 peritoneal fluid macrophages unveils two paths to resident macrophage repopulation with differing reliance on monocytes.
Alexandre Gallerand, Jichang Han, Rachel L Mintz, Jing Chen, Daniel D Lee, Mandy M Chan

bioRxiv· March 2025

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Molecular imaging of macrophage composition and dynamics in MASLD.
Bin Q Yang, Mandy M Chan, Gyu Seong Heo, Lanlan Lou, Hannah Luehmann

JHEP Rep· December 2024

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Long-term liver-related outcomes and liver stiffness progression of statin usage in steatotic liver disease.
Xiao-Dong Zhou, Seung Up Kim, Terry Cheuk-Fung Yip, Salvatore Petta, Atsushi Nakajima, Wah Kheong Chan, Mandy Sau-Wai Chan

Gut· October 2024

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Evaluation of a Novel Dermal Cooling System for the Treatment of Benign Pigmented Lesions in Asians.
Christina S M Wong, Mandy W M Chan, Samantha Y N Shek, Chi Keung Yeung, Henry H L Chan

Lasers Surg Med· August 2024

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Cutting Edge: Hepatic Stellate Cells Drive the Phenotype of Monocyte-derived Macrophages to Regulate Liver Fibrosis in Metabolic Dysfunction-associated Steatohepatitis.
Mandy M Chan, Li He, Brian N Finck, Joel D Schilling, Sabine Daemen

J Immunol· August 2024

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Vibration-Controlled Transient Elastography Scores to Predict Liver-Related Events in Steatotic Liver Disease.
Huapeng Lin, Hye Won Lee, Terry Cheuk-Fung Yip, Emmanuel Tsochatzis, Salvatore Petta, Wah-Kheong Chan, Mandy Sau-Wai Chan

JAMA· April 2024

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The use of fractional radiofrequency in Asian patients to improve skin texture.
Mandy W M Chan, Agnes W S Chan, Christina S M Wong, Samantha Y N Shek, Chi Keung Yeung, Henry H L Chan

Lasers Surg Med· February 2024

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Human serous cavity macrophages and dendritic cells possess counterparts in the mouse with a distinct distribution between species.
Jichang Han, Alexandre Gallerand, Emma C Erlich, Beth A Helmink, Iris Mair, Mandy M Chan

Nat Immunol· January 2024

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SON is an essential mA target for hematopoietic stem cell fate.
Hanzhi Luo, Mariela Cortés-López, Cyrus L Tam, Michael Xiao, Isaac Wakiro, Mandy Chan, Kathryn Chang

Cell Stem Cell· December 2023

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Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease.
Mandy M Chan, Sabine Daemen, Joseph W Beals, Marina Terekhova, Bin Q Yang

JHEP Rep· November 2023

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Financial well-being as a mediator of the relationship between multimorbidity and health-related quality of life in people with cancer.
Winnie K W So, Doreen W H Au, Dorothy N S Chan, Marques S N Ng, Kai Chow Choi, Mandy Chan, Maggie Chan, Raymond J Chan

Cancer Med· July 2023

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