Publications by authors named "Manjinder Lall"

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Enantioselective Single and Dual α-C-H Bond Functionalization of Cyclic Amines via Enzymatic Carbene Transfer.
Xinkun Ren, Bo M Couture, Ningyu Liu, Manjinder S Lall, Jeffrey T Kohrt

J Am Chem Soc· January 2023

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Pharmacokinetics, mass balance, metabolism, and excretion of the liver-targeted acetyl-CoA carboxylase inhibitor PF-05221304 (clesacostat) in humans.
Tim F Ryder, Arthur Bergman, Amanda King-Ahmad, Neeta B Amin, Manjinder S Lall

Xenobiotica· March 2022

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Toward the assembly and characterization of an encoded library hit confirmation platform: Bead-Assisted Ligand Isolation Mass Spectrometry (BALI-MS).
Anokha S Ratnayake, Mark E Flanagan, Timothy L Foley, Scott L Hultgren, Justin Bellenger, Manjinder S Lall

Bioorg Med Chem· July 2021

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Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure-Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H Receptor Inverse Agonist.
Manjinder S Lall, Asser Bassyouni, James Bradow, Maria Brown, Mark Bundesmann

J Med Chem· July 2020

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Utilizing on- and off-line monitoring tools to follow a kinetic resolution step during flow synthesis.
Kathleen A Farley, Usa Reilly, Dennis P Anderson, Brian P Boscoe, Mark W Bundesmann, Manjinder S Lall

Magn Reson Chem· April 2017

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Pyridone-conjugated monobactam antibiotics with gram-negative activity.
Matthew F Brown, Mark J Mitton-Fry, Joel T Arcari, Rose Barham, Jeffrey Casavant, Manjinder S Lall

J Med Chem· July 2013

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Novel monobactams utilizing a siderophore uptake mechanism for the treatment of gram-negative infections.
Mark J Mitton-Fry, Joel T Arcari, Matthew F Brown, Jeffrey M Casavant, Steven M Finegan, Manjinder S Lall

Bioorg Med Chem Lett· September 2012

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Stereoselective synthesis of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile.
Manjinder S Lall, Garrett Hoge, Tuan P Tran, William Kissel, Sean T Murphy

J Org Chem· May 2012

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Preparation, gram-negative antibacterial activity, and hydrolytic stability of novel siderophore-conjugated monocarbam diols.
Mark E Flanagan, Steven J Brickner, Manjinder Lall, Jeffrey Casavant, Laura Deschenes

ACS Med Chem Lett· May 2011

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Diversification of a β-Lactam Pharmacophore via Allylic C-H Amination: Accelerating Effect of Lewis Acid Co-Catalyst.
Xiangbing Ben Qi, Grant T Rice, Manjinder S Lall, Mark S Plummer, M Christina White

Tetrahedron· June 2010

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The use of biochemical and biophysical tools for triage of high-throughput screening hits - A case study with Escherichia coli phosphopantetheine adenylyltransferase.
J Richard Miller, Venkataraman Thanabal, Michael M Melnick, Manjinder Lall, Charles Donovan

Chem Biol Drug Des· May 2010

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5-(2-Pyrimidinyl)-imidazo[1,2-a]pyridines are antibacterial agents targeting the ATPase domains of DNA gyrase and topoisomerase IV.
Jeremy T Starr, Richard J Sciotti, Debra L Hanna, Michael D Huband, Lisa M Mullins, Manjinder S Lall

Bioorg Med Chem Lett· September 2009

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Synthesis and SAR of novel conformationally-restricted oxazolidinones possessing gram-positive and fastidious gram-negative antibacterial activity. Part 1: Substituted pyrazoles.
Frederick E Boyer, J V N Vara Prasad, Allison L Choy, Louis Chupak, Michael R Dermyer, Manjinder S Lall

Bioorg Med Chem Lett· August 2007

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Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site.
Jiang Yin, Ernst M Bergmann, Maia M Cherney, Manjinder S Lall, Rajendra P Jain

J Mol Biol· December 2005

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Inhibitors of 3C cysteine proteinases from Picornaviridae.
Manjinder S Lall, Rajendra P Jain, John C Vederas

Curr Top Med Chem· January 2005

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Serine and threonine beta-lactones: a new class of hepatitis A virus 3C cysteine proteinase inhibitors.
Manjinder S Lall, Yeeman K Ramtohul, Michael N G James, John C Vederas

J Org Chem· March 2002

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