Publications by authors named "Manu Setty"

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Molecular profiling of adult C. elegans glia across sexes by single-nuclear RNA-seq.
Maria D Purice, Elgene J A Quitevis, R Sean Manning, Liza J Severs, Nina-Tuyen Tran, Manu Setty

Dev Cell· October 2025

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Patterns of intra- and intertumor phenotypic heterogeneity in lethal prostate cancer.
Martine P Roudier, Roman Gulati, Erolcan Sayar, Radhika A Patel, Micah Tratt, Manu Setty

J Clin Invest· August 2025

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Comparing phenotypic manifolds with Kompot: Detecting differential abundance and gene expression at single-cell resolution.
Dominik J Otto, Erica Arriaga-Gomez, Elana Thieme, Ruijin Yang, Stanley C Lee, Manu Setty

bioRxiv· June 2025

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Single-cell analysis of bidirectional reprogramming between early embryonic states identify mechanisms of differential lineage plasticities in mice.
Vidur Garg, Yang Yang, Sonja Nowotschin, Manu Setty, Eralda Salataj

Dev Cell· March 2025

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Age-related epithelial defects limit thymic function and regeneration.
Anastasia I Kousa, Lorenz Jahn, Kelin Zhao, Angel E Flores, Dante Acenas, Manu Setty

Nat Immunol· September 2024

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Quantifying cell-state densities in single-cell phenotypic landscapes using Mellon.
Dominik J Otto, Cailin Jordan, Brennan Dury, Christine Dien, Manu Setty

Nat Methods· July 2024

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Signals that control MAIT cell function in healthy and inflamed human tissues.
Andrew J Konecny, Yin Huang, Manu Setty, Martin Prlic

Immunol Rev· May 2024

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SEACells infers transcriptional and epigenomic cellular states from single-cell genomics data.
Sitara Persad, Zi-Ning Choo, Christine Dien, Noor Sohail, Ignas Masilionis, Manu Setty

Nat Biotechnol· December 2023

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DUX4 expression in cancer induces a metastable early embryonic totipotent program.
Andrew A Smith, Yee Nip, Sean R Bennett, Danielle C Hamm, Richard J L F Lemmers, Manu Setty

Cell Rep· September 2023

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Quantifying Cell-State Densities in Single-Cell Phenotypic Landscapes using Mellon.
Dominik Otto, Cailin Jordan, Brennan Dury, Christine Dien, Manu Setty

bioRxiv· July 2023

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Molecular heterogeneity of glia across sexes.
Maria D Purice, Elgene J A Quitevis, R Sean Manning, Liza J Severs, Nina-Tuyen Tran, Manu Setty

bioRxiv· March 2023

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Single-cell analysis of bidirectional reprogramming between early embryonic states reveals mechanisms of differential lineage plasticities.
Vidur Garg, Yang Yang, Sonja Nowotschin, Manu Setty, Ying-Yi Kuo

bioRxiv· March 2023

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Defining cellular population dynamics at single-cell resolution during prostate cancer progression.
Alexandre A Germanos, Sonali Arora, Ye Zheng, Erica T Goddard, Ilsa M Coleman, Manu Setty

Elife· December 2022

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Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling.
Joseph M Chan, Samir Zaidi, Jillian R Love, Jimmy L Zhao, Manu Setty

Science· September 2022

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CUT&Tag2for1: a modified method for simultaneous profiling of the accessible and silenced regulome in single cells.
Derek H Janssens, Dominik J Otto, Michael P Meers, Manu Setty, Kami Ahmad

Genome Biol· March 2022

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CellRank for directed single-cell fate mapping.
Marius Lange, Volker Bergen, Michal Klein, Manu Setty, Bernhard Reuter

Nat Methods· February 2022

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Tissue Schematics: A framework to decipher tissue architecture and assembly.
Manu Setty

Cell Syst· February 2022

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Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer's disease.
Sudha R Guttikonda, Lisa Sikkema, Jason Tchieu, Nathalie Saurat, Ryan M Walsh, Manu Setty

Nat Neurosci· March 2021

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Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-parenchymal Cell Lineages.
Jeremy Lotto, Sibyl Drissler, Rebecca Cullum, Wei Wei, Manu Setty

Cell· October 2020

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Regenerative lineages and immune-mediated pruning in lung cancer metastasis.
Ashley M Laughney, Jing Hu, Nathaniel R Campbell, Samuel F Bakhoum, Manu Setty

Nat Med· February 2020

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Author Correction: Characterization of cell fate probabilities in single-cell data with Palantir.
Manu Setty, Vaidotas Kiseliovas, Jacob Levine, Adam Gayoso, Linas Mazutis

Nat Biotechnol· October 2019

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The emergent landscape of the mouse gut endoderm at single-cell resolution.
Sonja Nowotschin, Manu Setty, Ying-Yi Kuo, Vincent Liu, Vidur Garg

Nature· May 2019

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Characterization of cell fate probabilities in single-cell data with Palantir.
Manu Setty, Vaidotas Kiseliovas, Jacob Levine, Adam Gayoso, Linas Mazutis

Nat Biotechnol· April 2019

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Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States.
Spencer C Wei, Roshan Sharma, Nana-Ama A S Anang, Jacob H Levine, Yang Zhao, Manu Setty

Immunity· April 2019

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Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment.
Elham Azizi, Ambrose J Carr, George Plitas, Andrew E Cornish, Catherine Konopacki, Manu Setty

Cell· August 2018

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