Publications by authors named "Manuel D Leonetti"

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Evaluation of De Vries et al.: Quantifying cellular shapes and how they correlate to cellular responses.
Manuel D Leonetti

Cell Syst· March 2025

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MicroVQA: A Multimodal Reasoning Benchmark for Microscopy-Based Scientific Research.
James Burgess, Jeffrey J Nirschl, Laura Bravo-Sánchez, Alejandro Lozano, Sanket Rajan Gupte, Manuel D Leonetti

ArXiv· March 2025

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Global organelle profiling reveals subcellular localization and remodeling at proteome scale.
Marco Y Hein, Duo Peng, Verina Todorova, Frank McCarthy, Kibeom Kim, Manuel D Leonetti

Cell· February 2025

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An SLC12A9-dependent ion transport mechanism maintains lysosomal osmolarity.
Roni Levin-Konigsberg, Koushambi Mitra, Kaitlyn Spees, AkshatKumar Nigam, Katherine Liu, Manuel D Leonetti

Dev Cell· January 2025

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Mantis: High-throughput 4D imaging and analysis of the molecular and physical architecture of cells.
Ivan E Ivanov, Eduardo Hirata-Miyasaki, Talon Chandler, Rasmi Cheloor-Kovilakam, Ziwen Liu, Manuel D Leonetti

PNAS Nexus· September 2024

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protoSpaceJAM: an open-source, customizable and web-accessible design platform for CRISPR/Cas insertional knock-in.
Duo Peng, Madhuri Vangipuram, Joan Wong, Manuel D Leonetti

Nucleic Acids Res· August 2024

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Mantis: high-throughput 4D imaging and analysis of the molecular and physical architecture of cells.
Ivan E Ivanov, Eduardo Hirata-Miyasaki, Talon Chandler, Rasmi Cheloor-Kovilakam, Ziwen Liu, Manuel D Leonetti

bioRxiv· June 2024

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An open-source FACS automation system for high-throughput cell biology.
Diane M Wiener, Emily Huynh, Ilakkiyan Jeyakumar, Sophie Bax, Samia Sama, Manuel D Leonetti

PLoS One· March 2024

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Cell biology is….
Julie A Theriot, Anne Simonsen, Iva Tolić, Manuel D Leonetti, Satyajit Mayor

Cell· January 2024

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Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq.
Sara Sunshine, Andreas S Puschnik, Joseph M Replogle, Matthew T Laurie, Jamin Liu, Manuel D Leonetti

Nat Commun· October 2023

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Oxaliplatin disrupts nucleolar function through biophysical disintegration.
H Broder Schmidt, Zane A Jaafar, B Erik Wulff, Jason J Rodencal, Kibeom Hong, Manuel D Leonetti

Cell Rep· November 2022

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Self-supervised deep learning encodes high-resolution features of protein subcellular localization.
Hirofumi Kobayashi, Keith C Cheveralls, Manuel D Leonetti, Loic A Royer

Nat Methods· August 2022

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Author Correction: Spatiotemporal dissection of the cell cycle with single-cell proteogenomics.
Diana Mahdessian, Anthony J Cesnik, Christian Gnann, Frida Danielsson, Lovisa Stenström, Manuel D Leonetti

Nature· August 2022

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Correlative imaging of the spatio-angular dynamics of biological systems with multimodal instant polarization microscope.
Ivan E Ivanov, Li-Hao Yeh, Juan A Perez-Bermejo, Janie R Byrum, James Y S Kim, Manuel D Leonetti

Biomed Opt Express· May 2022

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OpenCell: Endogenous tagging for the cartography of human cellular organization.
Nathan H Cho, Keith C Cheveralls, Andreas-David Brunner, Kibeom Kim, André C Michaelis, Manuel D Leonetti

Science· March 2022

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WASP integrates substrate topology and cell polarity to guide neutrophil migration.
Rachel M Brunetti, Gabriele Kockelkoren, Preethi Raghavan, George R R Bell, Derek Britain, Manuel D Leonetti

J Cell Biol· February 2022

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Split-wrmScarlet and split-sfGFP: tools for faster, easier fluorescent labeling of endogenous proteins in Caenorhabditis elegans.
Jérôme Goudeau, Catherine S Sharp, Jonathan Paw, Laura Savy, Manuel D Leonetti

Genetics· April 2021

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Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.
James K Nuñez, Jin Chen, Greg C Pommier, J Zachery Cogan, Joseph M Replogle, Manuel D Leonetti

Cell· April 2021

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Spatiotemporal dissection of the cell cycle with single-cell proteogenomics.
Diana Mahdessian, Anthony J Cesnik, Christian Gnann, Frida Danielsson, Lovisa Stenström, Manuel D Leonetti

Nature· February 2021

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Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory Pathway.
Noemi Jiménez-Rojo, Manuel D Leonetti, Valeria Zoni, Adai Colom, Suihan Feng

Curr Biol· October 2020

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Rapid deployment of SARS-CoV-2 testing: The CLIAHUB.
Emily D Crawford, Irene Acosta, Vida Ahyong, Erika C Anderson, Shaun Arevalo, Manuel D Leonetti

PLoS Pathog· October 2020

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Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder.
Lovisa Stenström, Diana Mahdessian, Christian Gnann, Anthony J Cesnik, Wei Ouyang, Manuel D Leonetti

Mol Syst Biol· August 2020

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Revealing architectural order with quantitative label-free imaging and deep learning.
Syuan-Ming Guo, Li-Hao Yeh, Jenny Folkesson, Ivan E Ivanov, Anitha P Krishnan, Manuel D Leonetti

Elife· July 2020

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Pervasive functional translation of noncanonical human open reading frames.
Jin Chen, Andreas-David Brunner, J Zachery Cogan, James K Nuñez, Alexander P Fields, Manuel D Leonetti

Science· March 2020

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Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation.
John J Chen, Diane L Nathaniel, Preethi Raghavan, Maxine Nelson, Ruilin Tian, Manuel D Leonetti

J Biol Chem· December 2019

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