Publications by authors named "Manuel Rodriguez-Paredes"

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Loss of YTHDC1 mA reading function promotes invasiveness in urothelial carcinoma of the bladder.
Jinyun Xu, Jonas Koch, Claudia Schmidt, Malin Nientiedt, Manuel Neuberger

Exp Mol Med· February 2025

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Analysis of population heterogeneity in CHO cells by genome-wide DNA methylation analysis and by multi-modal single-cell sequencing.
Elias Böhl, Günter Raddatz, Suki Roy, Lingzhi Huang, Jasrene Kaur Sandhu

J Biotechnol· December 2024

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Functionally distinct cancer-associated fibroblast subpopulations establish a tumor promoting environment in squamous cell carcinoma.
Sabrina Schütz, Llorenç Solé-Boldo, Carlota Lucena-Porcel, Jochen Hoffmann, Alexander Brobeil

Nat Commun· September 2023

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Reinvestigating the clinical relevance of the mA writer METTL3 in urothelial carcinoma of the bladder.
Jonas Koch, Manuel Neuberger, Martina Schmidt-Dengler, Jinyun Xu, Vitor Coutinho Carneiro

iScience· August 2023

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Differentiation-related epigenomic changes define clinically distinct keratinocyte cancer subclasses.
Llorenç Solé-Boldo, Günter Raddatz, Julian Gutekunst, Oliver Gilliam, Felix Bormann

Mol Syst Biol· September 2022

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The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate TGFβ and Hippo pathways.
Elena Gómez-Marín, Melanija Posavec-Marjanović, Laura Zarzuela, Laura Basurto-Cayuela, José A Guerrero-Martínez

Nucleic Acids Res· September 2022

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Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin.
Elisa Espinet, Zuguang Gu, Charles D Imbusch, Nathalia A Giese, Magdalena Büscher

Cancer Discov· March 2021

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Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford progeria syndrome.
Florian Köhler, Felix Bormann, Günter Raddatz, Julian Gutekunst, Samuel Corless

Genome Med· May 2020

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Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming.
Llorenç Solé-Boldo, Günter Raddatz, Sabrina Schütz, Jan-Philipp Mallm, Karsten Rippe

Commun Biol· April 2020

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DNA Methylation in Epidermal Differentiation, Aging, and Cancer.
Florian Köhler, Manuel Rodríguez-Paredes

J Invest Dermatol· January 2020

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The importance of non-histone protein methylation in cancer therapy.
Manuel Rodríguez-Paredes, Frank Lyko

Nat Rev Mol Cell Biol· October 2019

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Transforming growth factor β1-mediated functional inhibition of mesenchymal stromal cells in myelodysplastic syndromes and acute myeloid leukemia.
Stefanie Geyh, Manuel Rodríguez-Paredes, Paul Jäger, Annemarie Koch, Felix Bormann

Haematologica· September 2018

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Cell-of-Origin DNA Methylation Signatures Are Maintained during Colorectal Carcinogenesis.
Felix Bormann, Manuel Rodríguez-Paredes, Felix Lasitschka, Dominic Edelmann, Tanja Musch

Cell Rep· June 2018

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Epigenetically Regulated Chromosome 14q32 miRNA Cluster Induces Metastasis and Predicts Poor Prognosis in Lung Adenocarcinoma Patients.
Margarita González-Vallinas, Manuel Rodríguez-Paredes, Marco Albrecht, Carsten Sticht, Damian Stichel

Mol Cancer Res· March 2018

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Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin.
Manuel Rodríguez-Paredes, Felix Bormann, Günter Raddatz, Julian Gutekunst, Carlota Lucena-Porcel

Nat Commun· February 2018

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Impact of DLK1-DIO3 imprinted cluster hypomethylation in smoker patients with lung cancer.
Sonia Molina-Pinelo, Ana Salinas, Nicolás Moreno-Mata, Irene Ferrer, Rocío Suarez

Oncotarget· January 2018

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-associated DNA hypermethylation in acute myeloid leukemia reflects differentiation blockage rather than inhibition of TET-mediated demethylation.
Laura Wiehle, Günter Raddatz, Stefan Pusch, Julian Gutekunst, Andreas von Deimling

Cell Stress· September 2017

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Reduced DNA methylation patterning and transcriptional connectivity define human skin aging.
Felix Bormann, Manuel Rodríguez-Paredes, Sabine Hagemann, Himanshu Manchanda, Boris Kristof

Aging Cell· June 2016

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An increase in MECP2 dosage impairs neural tube formation.
Paolo Petazzi, Naiara Akizu, Alejandra García, Conchi Estarás, Alexia Martínez de Paz

Neurobiol Dis· July 2014

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The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes.
Alicia Subtil-Rodríguez, Elena Vázquez-Chávez, María Ceballos-Chávez, Manuel Rodríguez-Paredes, José I Martín-Subero

Nucleic Acids Res· February 2014

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p21 as a transcriptional co-repressor of S-phase and mitotic control genes.
Nuria Ferrándiz, Juan M Caraballo, Lucía García-Gutierrez, Vikram Devgan, Manuel Rodriguez-Paredes

PLoS One· December 2012

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Control of neuronal differentiation by sumoylation of BRAF35, a subunit of the LSD1-CoREST histone demethylase complex.
María Ceballos-Chávez, Sabrina Rivero, Pablo García-Gutiérrez, Manuel Rodríguez-Paredes, Mario García-Domínguez

Proc Natl Acad Sci U S A· May 2012

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A combined epigenetic therapy equals the efficacy of conventional chemotherapy in refractory advanced non-small cell lung cancer.
Manuel Rodríguez-Paredes, Manel Esteller

Cancer Discov· December 2011

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Cancer epigenetics reaches mainstream oncology.
Manuel Rodríguez-Paredes, Manel Esteller

Nat Med· March 2011

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