Publications by authors named "Marc Derive"

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Tumor-dependent myeloid and lymphoid cell recruitment in genO-BRGSF-HIS mice: a novel tool for evaluating immunotherapies.
Gaëlle H Martin, Siham Hedir, Florent Creusat, Alexis Gonon, Amélie Marguier, Marc Derive

Front Immunol· October 2025

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The potential of targeting TREM-1 in IBD.
Emilie Vinolo, Marine Maillefer, Lucie Jolly, Nelly Colné, Gregory Meiffren, Marc Derive

Adv Pharmacol· November 2024

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THBS1 myeloid cells expand in SLD hepatocellular carcinoma and contribute to immunosuppression and unfavorable prognosis through TREM1.
Julie Giraud, Domitille Chalopin, Eloïse Ramel, Thomas Boyer, Atika Zouine, Marc Derive

Cell Rep· February 2024

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Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial.
Bruno François, Simon Lambden, Tom Fivez, Sebastien Gibot, Marc Derive

Lancet Respir Med· October 2023

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Soluble TREM-1 plasma concentration predicts poor outcome in COVID-19 patients.
Sébastien Gibot, Thomas Lafon, Laurent Jacquin, Benjamin Lefevre, Antoine Kimmoun, Marc Derive

Intensive Care Med Exp· August 2023

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Evaluation of the efficacy and safety of TREM-1 inhibition with nangibotide in patients with COVID-19 receiving respiratory support: the ESSENTIAL randomised, double-blind trial.
Bruno François, Simon Lambden, Jean-Jacques Garaud, Marc Derive, Jean-Marie Grouin

EClinicalMedicine· June 2023

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Dexamethasone Modulates the Cytokine Response but Not COVID-19-Induced Coagulopathy in Critically Ill.
Mélanie Dechamps, Julien De Poortere, Marie Octave, Audrey Ginion, Valentine Robaux, Marc Derive

Int J Mol Sci· April 2023

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Persistently Elevated Soluble Triggering Receptor Expressed on Myeloid Cells 1 and Decreased Monocyte Human Leucocyte Antigen DR Expression Are Associated With Nosocomial Infections in Septic Shock Patients.
Matthieu Venet, Frank Bidar, Marc Derive, Benjamin Delwarde, Céline Monard

Crit Care Explor· March 2023

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Triggering receptor expressed on myeloid cells-1 deletion in mice attenuates high-fat diet-induced obesity.
Benjamin Brustolin, Nina Touly, Marine Maillefer, Lola Parisot, Elisa Di Pillo, Marc Derive

Front Endocrinol (Lausanne)· January 2023

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Triggering Receptors Expressed on Myeloid Cells 1 : Our New Partner in Human Oncology?
Marie Muller, Vincent Haghnejad, Anthony Lopez, Angelica Tiotiu, Stéphane Renaud, Marc Derive

Front Oncol· July 2022

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Oxidative stress-induced endothelial dysfunction and decreased vascular nitric oxide in COVID-19 patients.
Virginie Montiel, Irina Lobysheva, Ludovic Gérard, Marjorie Vermeersch, David Perez-Morga, Marc Derive

EBioMedicine· March 2022

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Inflammation-Induced Coagulopathy Substantially Differs Between COVID-19 and Septic Shock: A Prospective Observational Study.
Mélanie Dechamps, Julien De Poortere, Manon Martin, Laurent Gatto, Aurélie Daumerie, Marc Derive

Front Med (Lausanne)· January 2022

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Plasma and genetic determinants of soluble TREM-1 and major adverse cardiovascular events in a prospective cohort of acute myocardial infarction patients. Results from the FAST-MI 2010 study.
Hafid Ait-Oufella, Mengyao Yu, Salma Kotti, Adrien Georges, Marie Vandestienne, Marc Derive

Int J Cardiol· December 2021

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sTREM-1 is a specific biomarker of TREM-1 pathway activation.
Lucie Jolly, Kévin Carrasco, Margarita Salcedo-Magguilli, Jean-Jacques Garaud, Simon Lambden, Marc Derive

Cell Mol Immunol· August 2021

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Increased sTREM-1 plasma concentrations are associated with poor clinical outcomes in patients with COVID-19.
Aline H de Nooijer, Inge Grondman, Simon Lambden, Emma J Kooistra, Nico A F Janssen, Marc Derive

Biosci Rep· July 2021

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Rationale and protocol for the efficacy, safety and tolerability of nangibotide in patients with septic shock (ASTONISH) phase IIb randomised controlled trial.
Bruno Francois, Simon Lambden, Sebastien Gibot, Marc Derive, Aurelie Olivier

BMJ Open· July 2021

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Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs release in sepsis.
Amir Boufenzer, Kevin Carrasco, Lucie Jolly, Benjamin Brustolin, Elisa Di-Pillo, Marc Derive

Cell Mol Immunol· February 2021

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TREM-1 orchestrates angiotensin II-induced monocyte trafficking and promotes experimental abdominal aortic aneurysm.
Marie Vandestienne, Yujiao Zhang, Icia Santos-Zas, Rida Al-Rifai, Jeremie Joffre, Marc Derive

J Clin Invest· January 2021

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Triggering Receptor Expressed on Myeloid Cells-1 Inhibitor Targeted to Endothelium Decreases Cell Activation.
Sébastien Gibot, Lucie Jolly, Jérémie Lemarié, Kevin Carrasco, Marc Derive

Front Immunol· October 2020

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Nangibotide in patients with septic shock: a Phase 2a randomized controlled clinical trial.
Bruno François, Xavier Wittebole, Ricard Ferrer, Jean-Paul Mira, Thierry Dugernier, Marc Derive

Intensive Care Med· July 2020

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Inhibition of triggering receptor expressed on myeloid cells-1 impairs thrombin generation.
Elisa Di Pillo, Kevin Carrasco, Benjamin Brustolin, Amir Boufenzer, Lucie Jolly, Marc Derive

J Thromb Haemost· February 2020

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TREM-1 multimerization is essential for its activation on monocytes and neutrophils.
Kevin Carrasco, Amir Boufenzer, Lucie Jolly, Helene Le Cordier, Guanbo Wang, Marc Derive

Cell Mol Immunol· May 2019

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A first-in-man safety and pharmacokinetics study of nangibotide, a new modulator of innate immune response through TREM-1 receptor inhibition.
Valerie Cuvier, Ulrike Lorch, Stephan Witte, Aurelie Olivier, Sebastien Gibot, Marc Derive

Br J Clin Pharmacol· October 2018

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Targeted endothelial gene deletion of triggering receptor expressed on myeloid cells-1 protects mice during septic shock.
Lucie Jolly, Kevin Carrasco, Marc Derive, Jérémie Lemarié, Amir Boufenzer

Cardiovasc Res· May 2018

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Triggering Receptor Expressed on Myeloid cells-1: a new player in platelet aggregation.
Lucie Jolly, Jeremie Lemarie, Kevin Carrasco, Batric Popovic, Marc Derive

Thromb Haemost· August 2017

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