Publications by authors named "Stephan Witte"

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Enibarcimab for the treatment of septic shock in patients selected by a combination of the biomarkers bio-ADM and DPP3: A prespecified subgroup analysis of the AdrenOSS-2 trial.
Claudia Knothe, Stephan Witte, Andreas Bergmann, Alexandre Mebazaa, Pierre-Francois Laterre

J Crit Care· August 2025

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Enhancing sepsis biomarker development: key considerations from public and private perspectives.
Jean-Francois Llitjos, Enitan D Carrol, Marcin F Osuchowski, Marc Bonneville, Brendon P Scicluna, Stephan Witte

Crit Care· July 2024

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Rationale and protocol for the efficacy, safety and tolerability of nangibotide in patients with septic shock (ASTONISH) phase IIb randomised controlled trial.
Bruno Francois, Simon Lambden, Sebastien Gibot, Marc Derive, Aurelie Olivier, Stephan Witte

BMJ Open· July 2021

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Nangibotide in patients with septic shock: a Phase 2a randomized controlled clinical trial.
Bruno François, Xavier Wittebole, Ricard Ferrer, Jean-Paul Mira, Thierry Dugernier, Stephan Witte

Intensive Care Med· July 2020

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PICOT binding to the polycomb group protein, EED, alters H3K27 methylation at the MYT1 PRC2 target gene.
Pinakin Pandya, Ronit Pasvolsky, Yael Babichev, Alex Braiman, Stephan Witte

Biochem Biophys Res Commun· February 2019

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A first-in-man safety and pharmacokinetics study of nangibotide, a new modulator of innate immune response through TREM-1 receptor inhibition.
Valerie Cuvier, Ulrike Lorch, Stephan Witte, Aurelie Olivier, Sebastien Gibot

Br J Clin Pharmacol· October 2018

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Safety and Efficacy of a Novel Microbial Lipase in Patients with Exocrine Pancreatic Insufficiency due to Cystic Fibrosis: A Randomized Controlled Clinical Trial.
James E Heubi, David Schaeffer, Richard C Ahrens, Natalie Sollo, Steven Strausbaugh, Stephan Witte

J Pediatr· September 2016

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Low-dose prednisone chronotherapy for rheumatoid arthritis: a randomised clinical trial (CAPRA-2).
Frank Buttgereit, Daksha Mehta, John Kirwan, Jacek Szechinski, Maarten Boers, Stephan Witte

Ann Rheum Dis· February 2013

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Hypothalamus-pituitary-adrenal axis function in patients with rheumatoid arthritis treated with nighttime-release prednisone.
Rieke Alten, Gisela Döring, Maurizio Cutolo, Erika Gromnica-Ihle, Stephan Witte

J Rheumatol· October 2010

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Targeting pathophysiological rhythms: prednisone chronotherapy shows sustained efficacy in rheumatoid arthritis.
Frank Buttgereit, Gisela Doering, Achim Schaeffler, Stephan Witte, Stanislaw Sierakowski

Ann Rheum Dis· July 2010

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Efficacy of modified-release versus standard prednisone to reduce duration of morning stiffness of the joints in rheumatoid arthritis (CAPRA-1): a double-blind, randomised controlled trial.
Frank Buttgereit, Gisela Doering, Achim Schaeffler, Stephan Witte, Stanislaw Sierakowski

Lancet· January 2008

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Roflumilast--an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial.
Klaus F Rabe, Eric D Bateman, Denis O'Donnell, Stephan Witte, Dirk Bredenbröker

Lancet· October 2005

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