Publications by authors named "Marc Fabian"

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tRNA-overlapping long non-coding RNA loci repress codon-biased genes.
Sameen Ahmed, Jacob L Fine, Jordan J Chalmers, Katerina Kiriakopulos, Lindsay A Clarke, Marc R Fabian

Cell Rep· October 2025

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DICER1 in pediatric and adult cancer predisposition populations: Prevalence, phenotypes, and mosaicism.
Lluis Salvador, Jesús Del Valle, Eduard Dorca, Anne-Sophie Chong, Anne-Laure Chong, Marc R Fabian

Genet Med· May 2025

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Extraskeletal chondroma of the toe in a child with DICER1 tumor predisposition syndrome: support for a dominant negative mechanism.
Dylan Pelletier, Nelly Sabbaghian, Anne-Laure Chong, John R Priest, Yomna Elsheikh Ahmed, Marc R Fabian

Virchows Arch· June 2024

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The EDC4-XRN1 interaction controls P-body dynamics to link mRNA decapping with decay.
William R Brothers, Farah Ali, Sam Kajjo, Marc R Fabian

EMBO J· November 2023

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DICER1 platform domain missense variants inhibit miRNA biogenesis and lead to tumor susceptibility.
Dylan Pelletier, Anne-Laure Chong, Mona Wu, Leora Witkowski, Sophie Albert, Marc R Fabian

NAR Cancer· September 2023

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Uncovering a mammalian neural-specific poly(A) binding protein with unique properties.
Sahil Sharma, Sam Kajjo, Zineb Harra, Benedeta Hasaj, Victoria Delisle, Marc R Fabian

Genes Dev· August 2023

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miRNA biogenesis and inherited disorders: clinico-molecular insights.
Dylan Pelletier, Barbara Rivera, Marc R Fabian, William D Foulkes

Trends Genet· May 2023

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Development of a Virtual Reality Tool for the Treatment of Pediatric Patients in the ICU.
Laura Raya, Juan Jesus Ruiz, Marc Fabian, Adrian Ron, Javier Garcia

IEEE Comput Graph Appl· April 2023

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P-bodies directly regulate MARF1-mediated mRNA decay in human cells.
William R Brothers, Hana Fakim, Sam Kajjo, Marc R Fabian

Nucleic Acids Res· July 2022

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PABP prevents the untimely decay of select mRNA populations in human cells.
Sam Kajjo, Sahil Sharma, Shan Chen, William R Brothers, Megan Cott, Marc R Fabian

EMBO J· March 2022

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A Cell-Free System for Investigating Human MARF1 Endonuclease Activity.
Hana Fakim, Marc R Fabian

Methods Mol Biol· March 2021

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A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay.
William R Brothers, Steven Hebert, Claudia L Kleinman, Marc R Fabian

Elife· June 2020

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DGCR8 microprocessor defect characterizes familial multinodular goiter with schwannomatosis.
Barbara Rivera, Javad Nadaf, Somayyeh Fahiminiya, Maria Apellaniz-Ruiz, Avi Saskin, Marc R Fabian

J Clin Invest· March 2020

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Communication Is Key: 5'-3' Interactions that Regulate mRNA Translation and Turnover.
Hana Fakim, Marc R Fabian

Adv Exp Med Biol· December 2019

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Of seeds and supplements: structural insights into extended microRNA-target pairing.
Marc R Fabian

EMBO J· July 2019

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Leukodystrophy-associated mutations down-regulate the RNA polymerase III transcript and important regulatory RNA .
Karine Choquet, Diane Forget, Elisabeth Meloche, Marie-Josée Dicaire, Geneviève Bernard, Marc R Fabian

J Biol Chem· May 2019

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Mesenchymal Hamartoma of the Liver and DICER1 Syndrome.
Maria Apellaniz-Ruiz, Maria Segni, Matthias Kettwig, Sylvia Glüer, Dylan Pelletier, Marc R Fabian

N Engl J Med· May 2019

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Mechanistic Insights into MicroRNA-Mediated Gene Silencing.
Thomas F Duchaine, Marc R Fabian

Cold Spring Harb Perspect Biol· March 2019

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Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs.
Tamiko Nishimura, Hana Fakim, Tobias Brandmann, Ji-Young Youn, Anne-Claude Gingras, Marc R Fabian

Nucleic Acids Res· December 2018

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Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes.
Tobias Brandmann, Hana Fakim, Zoya Padamsi, Ji-Young Youn, Anne-Claude Gingras, Marc R Fabian

EMBO J· April 2018

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High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.
Ji-Young Youn, Wade H Dunham, Seo Jung Hong, James D R Knight, Mikhail Bashkurov, Marc Fabian

Mol Cell· February 2018

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Anaplastic sarcomas of the kidney are characterized by DICER1 mutations.
Mona K Wu, Gordan M Vujanic, Somayyeh Fahiminiya, Noriko Watanabe, Paul S Thorner, Marc R Fabian

Mod Pathol· January 2018

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Structural Dynamics of the GW182 Silencing Domain Including its RNA Recognition motif (RRM) Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry.
Maja K Cieplak-Rotowska, Krzysztof Tarnowski, Marcin Rubin, Marc R Fabian, Nahum Sonenberg

J Am Soc Mass Spectrom· January 2018

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Cap-binding protein 4EHP effects translation silencing by microRNAs.
Clément Chapat, Seyed Mehdi Jafarnejad, Edna Matta-Camacho, Geoffrey G Hesketh, Idit A Gelbart, Marc R Fabian

Proc Natl Acad Sci U S A· May 2017

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CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair.
Khalid Hilmi, Maïka Jangal, Maud Marques, Tiejun Zhao, Amine Saad, Marc R Fabian

Sci Adv· May 2017

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