Publications by authors named "Diane Forget"

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MAGPIE: A Machine Learning Approach to Decipher Protein-Protein Interactions in Human Plasma.
Emily Hashimoto-Roth, Diane Forget, Vanessa P Gaspar, Steffany A L Bennett, Marie-Soleil Gauthier

J Proteome Res· February 2025

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ARMC5 controls the degradation of most Pol II subunits, and ARMC5 mutation increases neural tube defect risks in mice and humans.
Hongyu Luo, Linjiang Lao, Kit Sing Au, Hope Northrup, Xiao He, Diane Forget

Genome Biol· January 2024

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Variants in impair LSM complexes assembly, neurodevelopment in zebrafish and may be associated with an ultra-rare neurological disease.
Alexa Derksen, Hung-Yu Shih, Diane Forget, Lama Darbelli, Luan T Tran

HGG Adv· July 2021

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Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor).
Ali Ben Djoudi Ouadda, Marie-Soleil Gauthier, Delia Susan-Resiga, Emmanuelle Girard, Rachid Essalmani, Diane Forget

Arterioscler Thromb Vasc Biol· October 2019

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Leukodystrophy-associated mutations down-regulate the RNA polymerase III transcript and important regulatory RNA .
Karine Choquet, Diane Forget, Elisabeth Meloche, Marie-Josée Dicaire, Geneviève Bernard

J Biol Chem· May 2019

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Bi-allelic Mutations in EPRS, Encoding the Glutamyl-Prolyl-Aminoacyl-tRNA Synthetase, Cause a Hypomyelinating Leukodystrophy.
Marisa I Mendes, Mariana Gutierrez Salazar, Kether Guerrero, Isabelle Thiffault, Gajja S Salomons, Diane Forget

Am J Hum Genet· April 2018

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Absence of neurological abnormalities in mice homozygous for the Polr3a G672E hypomyelinating leukodystrophy mutation.
Karine Choquet, Sharon Yang, Robyn D Moir, Diane Forget, Roxanne Larivière

Mol Brain· April 2017

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Abnormal expression of RNA polymerase II-associated proteins in muscle of patients with myofibrillar myopathies.
Valeria Guglielmi, Matteo Marini, Émilie Fiola Masson, Manuela Malatesta, Diane Forget

Histopathology· December 2015

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Recessive mutations in POLR1C cause a leukodystrophy by impairing biogenesis of RNA polymerase III.
Isabelle Thiffault, Nicole I Wolf, Diane Forget, Kether Guerrero, Luan T Tran

Nat Commun· July 2015

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Nuclear import of RNA polymerase II is coupled with nucleocytoplasmic shuttling of the RNA polymerase II-associated protein 2.
Diane Forget, Andrée-Anne Lacombe, Philippe Cloutier, Mathieu Lavallée-Adam, Mathieu Blanchette

Nucleic Acids Res· August 2013

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Discovery of cell compartment specific protein-protein interactions using affinity purification combined with tandem mass spectrometry.
Mathieu Lavallée-Adam, Justine Rousseau, Céline Domecq, Annie Bouchard, Diane Forget

J Proteome Res· January 2013

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The protein interaction network of the human transcription machinery reveals a role for the conserved GTPase RPAP4/GPN1 and microtubule assembly in nuclear import and biogenesis of RNA polymerase II.
Diane Forget, Andrée-Anne Lacombe, Philippe Cloutier, Racha Al-Khoury, Annie Bouchard

Mol Cell Proteomics· December 2010

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High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes.
Philippe Cloutier, Racha Al-Khoury, Mathieu Lavallée-Adam, Denis Faubert, Heng Jiang, Diane Forget

Methods· August 2009

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Use of site-specific protein-DNA photocrosslinking of purified complexes to analyze the topology of the RNA polymerase II transcription initiation complex.
Diane Forget, Céline Domecq, Benoit Coulombe

Methods Mol Biol· June 2009

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Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription.
Marilena Cojocaru, Célia Jeronimo, Diane Forget, Annie Bouchard, Dominique Bergeron

Biochem J· January 2008

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Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
Célia Jeronimo, Diane Forget, Annie Bouchard, Qintong Li, Gordon Chua

Mol Cell· July 2007

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RPAP1, a novel human RNA polymerase II-associated protein affinity purified with recombinant wild-type and mutated polymerase subunits.
Célia Jeronimo, Marie-France Langelier, Mahel Zeghouf, Marilena Cojocaru, Dominique Bergeron, Diane Forget

Mol Cell Biol· August 2004

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Ordered conformational changes in damaged DNA induced by nucleotide excision repair factors.
Angels Tapias, Jerome Auriol, Diane Forget, Jacqueline H Enzlin, Orlando D Schärer

J Biol Chem· April 2004

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Site-specific protein-DNA photocross-linking of purified complexes: topology of the RNA polymerase II transcription initiation complex.
Diane Forget, Benoit Coulombe

Methods Enzymol· February 2004

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Photo-cross-linking of a purified preinitiation complex reveals central roles for the RNA polymerase II mobile clamp and TFIIE in initiation mechanisms.
Diane Forget, Marie-France Langelier, Cynthia Thérien, Vincent Trinh, Benoit Coulombe

Mol Cell Biol· February 2004

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