Publications by authors named "Marc Fiedler"

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VEL-dependent polymerization maintains the chromatin association of Polycomb proteins for the switch to epigenetic silencing.
Anna Schulten, Geng-Jen Jang, Alex Payne-Dwyer, Marc Fiedler, Mathias L Nielsen

Mol Cell· September 2025

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A CPF-like phosphatase module links transcription termination to chromatin silencing.
Eduardo Mateo-Bonmatí, Miguel Montez, Robert Maple, Marc Fiedler, Xiaofeng Fang

Mol Cell· June 2024

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Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism.
Daniel L Dunkelmann, Carlos Piedrafita, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler

Nature· January 2024

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Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity.
Elsa Franco-Echevarría, Trevor J Rutherford, Marc Fiedler, Caroline Dean, Mariann Bienz

J Biol Chem· November 2022

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Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Marc Fiedler, Elsa Franco-Echevarría, Anna Schulten, Mathias Nielsen, Trevor J Rutherford

Cell Rep· November 2022

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Biophysical Survey of Small-Molecule β-Catenin Inhibitors: A Cautionary Tale.
Michael A McCoy, Dominique Spicer, Neil Wells, Kurt Hoogewijs, Marc Fiedler

J Med Chem· May 2022

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Mechanism-based traps enable protease and hydrolase substrate discovery.
Shan Tang, Adam T Beattie, Lucie Kafkova, Gianluca Petris, Nicolas Huguenin-Dezot, Marc Fiedler

Nature· February 2022

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Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas.
Aswini Krishnan, Jean Berthelet, Emilie Renaud, Sebastian Rosigkeit, Ute Distler, Marc Fiedler

Nat Commun· April 2020

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DIX Domain Polymerization Drives Assembly of Plant Cell Polarity Complexes.
Maritza van Dop, Marc Fiedler, Sumanth Mutte, Jeroen de Keijzer, Lisa Olijslager

Cell· February 2020

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A direct heterotypic interaction between the DIX domains of Dishevelled and Axin mediates signaling to β-catenin.
Kumpei Yamanishi, Marc Fiedler, Shin-Ichi Terawaki, Yoshiki Higuchi, Mariann Bienz

Sci Signal· December 2019

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Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Miha Renko, Marc Fiedler, Trevor J Rutherford, Jonas V Schaefer, Andreas Plückthun

Proc Natl Acad Sci U S A· October 2019

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Arabidopsis FLL2 promotes liquid-liquid phase separation of polyadenylation complexes.
Xiaofeng Fang, Liang Wang, Ryo Ishikawa, Yaoxi Li, Marc Fiedler

Nature· May 2019

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Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.
Laurens M van Tienen, Juliusz Mieszczanek, Marc Fiedler, Trevor J Rutherford, Mariann Bienz

Elife· March 2017

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Correction: Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.
Laurens M van Tienen, Juliusz Mieszczanek, Marc Fiedler, Trevor Rutherford, Mariann Bienz

Elife· March 2017

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An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP.
Marc Fiedler, Michael Graeb, Juliusz Mieszczanek, Trevor J Rutherford, Christopher M Johnson

Elife· August 2015

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Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization.
Julia Madrzak, Marc Fiedler, Christopher M Johnson, Richard Ewan, Axel Knebel

Nat Commun· April 2015

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Competitive binding of a benzimidazole to the histone-binding pocket of the Pygo PHD finger.
Thomas C R Miller, Trevor J Rutherford, Kristian Birchall, Jasveen Chugh, Marc Fiedler

ACS Chem Biol· December 2014

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Evolutionary adaptation of the fly Pygo PHD finger toward recognizing histone H3 tail methylated at arginine 2.
Thomas C R Miller, Juliusz Mieszczanek, María José Sánchez-Barrena, Trevor J Rutherford, Marc Fiedler

Structure· December 2013

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Heterologous prime-boost immunizations with a virosomal and an alphavirus replicon vaccine.
Mateusz Walczak, Arjan de Mare, Annelies Riezebos-Brilman, Joke Regts, Baukje-Nynke Hoogeboom, Marc Fiedler

Mol Pharm· February 2011

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Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin.
Marc Fiedler, Carolina Mendoza-Topaz, Trevor J Rutherford, Juliusz Mieszczanek, Mariann Bienz

Proc Natl Acad Sci U S A· February 2011

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Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ.
Kerstin Dreier, René Scheiden, Barbara Lener, Daniela Ehehalt, Haymo Pircher, Marc Fiedler

Virology· January 2011

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Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor.
Thomas C R Miller, Trevor J Rutherford, Christopher M Johnson, Marc Fiedler, Mariann Bienz

J Mol Biol· September 2010

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Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.
Ciara Metcalfe, Ashraf E K Ibrahim, Michael Graeb, Marc de la Roche, Thomas Schwarz-Romond, Marc Fiedler

Cancer Res· August 2010

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The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2.
Gilles A Spoden, Dieter Morandell, Daniela Ehehalt, Marc Fiedler, Pidder Jansen-Dürr

J Cell Biochem· May 2009

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Human papillomavirus type 45 E7 is a transforming protein inducing retinoblastoma protein degradation and anchorage-independent cell cycle progression.
Dieter Morandell, Ursula Rostek, Veronique Bouvard, Beatriz Campo-Fernández, Marc Fiedler

Virology· September 2008

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