Publications by authors named "Trevor Rutherford"

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Wnt signalosome assembly is governed by conformational flexibility of Axin and by the AP2 clathrin adaptor.
Melissa V Gammons, Elsa Franco-Echevarría, Tie-Mei Li, Trevor J Rutherford, Miha Renko

Nat Commun· May 2025

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Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity.
Elsa Franco-Echevarría, Trevor J Rutherford, Marc Fiedler, Caroline Dean, Mariann Bienz

J Biol Chem· November 2022

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Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Marc Fiedler, Elsa Franco-Echevarría, Anna Schulten, Mathias Nielsen, Trevor J Rutherford

Cell Rep· November 2022

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Selective function of the PDZ domain of Dishevelled in noncanonical Wnt signalling.
Juliusz Mieszczanek, Helen Strutt, Trevor J Rutherford, David Strutt, Mariann Bienz

J Cell Sci· June 2022

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Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Ivan Rosa E Silva, Lucia Binó, Christopher M Johnson, Trevor J Rutherford, David Neuhaus

Structure· January 2022

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Analysis of ligand binding and resulting conformational changes in pyrophosphatase NUDT9.
Ellen Gattkowski, Trevor J Rutherford, Franziska Möckl, Andreas Bauche, Simon Sander

FEBS J· December 2021

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Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites.
Gonzalo J Beitia, Trevor J Rutherford, Stefan M V Freund, Hugh R Pelham, Mariann Bienz

Proc Natl Acad Sci U S A· June 2021

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Controlled Ligand Exchange Between Ruthenium Organometallic Cofactor Precursors and a Naïve Protein Scaffold Generates Artificial Metalloenzymes Catalysing Transfer Hydrogenation.
George S Biggs, Oskar James Klein, Sarah L Maslen, J Mark Skehel, Trevor J Rutherford

Angew Chem Int Ed Engl· May 2021

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FtsK in motion reveals its mechanism for double-stranded DNA translocation.
Nicolas L Jean, Trevor J Rutherford, Jan Löwe

Proc Natl Acad Sci U S A· June 2020

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Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Miha Renko, Marc Fiedler, Trevor J Rutherford, Jonas V Schaefer, Andreas Plückthun

Proc Natl Acad Sci U S A· October 2019

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Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2.
Ellen Gattkowski, Anke Johnsen, Andreas Bauche, Franziska Möckl, Frederike Kulow, Trevor J Rutherford

Biochim Biophys Acta Mol Cell Res· July 2019

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Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.
Laurens M van Tienen, Juliusz Mieszczanek, Marc Fiedler, Trevor J Rutherford, Mariann Bienz

Elife· March 2017

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Correction: Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.
Laurens M van Tienen, Juliusz Mieszczanek, Marc Fiedler, Trevor Rutherford, Mariann Bienz

Elife· March 2017

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Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Melissa V Gammons, Miha Renko, Christopher M Johnson, Trevor J Rutherford, Mariann Bienz

Mol Cell· October 2016

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Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay.
Melissa V Gammons, Trevor J Rutherford, Zachary Steinhart, Stephane Angers, Mariann Bienz

J Cell Sci· October 2016

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Experimental and Theoretical Evaluation of the Ethynyl Moiety as a Halogen Bioisostere.
Rainer Wilcken, Markus O Zimmermann, Matthias R Bauer, Trevor J Rutherford, Alan R Fersht

ACS Chem Biol· December 2015

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An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP.
Marc Fiedler, Michael Graeb, Juliusz Mieszczanek, Trevor J Rutherford, Christopher M Johnson

Elife· August 2015

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Competitive binding of a benzimidazole to the histone-binding pocket of the Pygo PHD finger.
Thomas C R Miller, Trevor J Rutherford, Kristian Birchall, Jasveen Chugh, Marc Fiedler

ACS Chem Biol· December 2014

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Structure of the SAS-6 cartwheel hub from Leishmania major.
Mark van Breugel, Rainer Wilcken, Stephen H McLaughlin, Trevor J Rutherford, Christopher M Johnson

Elife· January 2014

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Evolutionary adaptation of the fly Pygo PHD finger toward recognizing histone H3 tail methylated at arginine 2.
Thomas C R Miller, Juliusz Mieszczanek, María José Sánchez-Barrena, Trevor J Rutherford, Marc Fiedler

Structure· December 2013

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An essential role for the ATG8 ortholog LC3C in antibacterial autophagy.
Natalia von Muhlinen, Masato Akutsu, Benjamin J Ravenhill, Ágnes Foeglein, Stuart Bloor, Trevor J Rutherford

Autophagy· May 2013

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LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy.
Natalia von Muhlinen, Masato Akutsu, Benjamin J Ravenhill, Ágnes Foeglein, Stuart Bloor, Trevor J Rutherford

Mol Cell· November 2012

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Lithocholic acid is an endogenous inhibitor of MDM4 and MDM2.
Simon M Vogel, Matthias R Bauer, Andreas C Joerger, Rainer Wilcken, Tobias Brandt, Trevor J Rutherford

Proc Natl Acad Sci U S A· October 2012

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Halogen-enriched fragment libraries as leads for drug rescue of mutant p53.
Rainer Wilcken, Xiangrui Liu, Markus O Zimmermann, Trevor J Rutherford, Alan R Fersht

J Am Chem Soc· April 2012

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An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid.
Marc de la Roche, Trevor J Rutherford, Deepti Gupta, Dmitry B Veprintsev, Barbara Saxty

Nat Commun· February 2012

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