Publications by authors named "Marc Laburthe"

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Strategies for studying the ligand binding site of GPCRs: photoaffinity labeling of the VPAC1 receptor, a prototype of class B GPCRs.
Alain Couvineau, Yossan-Var Tan, Emilie Ceraudo, Marc Laburthe

Methods Enzymol· June 2013

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VPAC receptors: structure, molecular pharmacology and interaction with accessory proteins.
Alain Couvineau, Marc Laburthe

Br J Pharmacol· May 2012

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Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1.
Anthony J Harmar, Jan Fahrenkrug, Illana Gozes, Marc Laburthe, Victor May

Br J Pharmacol· May 2012

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Spatial proximity between the VPAC1 receptor and the amino terminus of agonist and antagonist peptides reveals distinct sites of interaction.
Emilie Ceraudo, Régine Hierso, Yossan-Var Tan, Samuel Murail, Christiane Rouyer-Fessard, Marc Laburthe

FASEB J· May 2012

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The orexin receptor OX(1)R in colon cancer: a promising therapeutic target and a new paradigm in G protein-coupled receptor signalling through ITIMs.
Marc Laburthe, Thierry Voisin

Br J Pharmacol· March 2012

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[How to turn a silent proapoptotic gene in a potent antitumoral target in colorectal cancer].
Marc Laburthe

Med Sci (Paris)· March 2012

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The family B1 GPCR: structural aspects and interaction with accessory proteins.
Alain Couvineau, Marc Laburthe

Curr Drug Targets· January 2012

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VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling.
Sandrine Passemard, Vincent El Ghouzzi, Hala Nasser, Catherine Verney, Guilan Vodjdani, Marc Laburthe

J Clin Invest· August 2011

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Aberrant expression of OX1 receptors for orexins in colon cancers and liver metastases: an openable gate to apoptosis.
Thierry Voisin, Aadil El Firar, Magali Fasseu, Christiane Rouyer-Fessard, Véronique Descatoire, Marc Laburthe

Cancer Res· May 2011

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Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease.
Magali Fasseu, Xavier Tréton, Cécile Guichard, Eric Pedruzzi, Dominique Cazals-Hatem, Marc Laburthe

PLoS One· October 2010

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Discovery of a functional immunoreceptor tyrosine-based switch motif in a 7-transmembrane-spanning receptor: role in the orexin receptor OX1R-driven apoptosis.
Aadil El Firar, Thierry Voisin, Christiane Rouyer-Fessard, Mariano A Ostuni, Alain Couvineau, Marc Laburthe

FASEB J· December 2009

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Molecular and conformational determinants of pituitary adenylate cyclase-activating polypeptide (PACAP) for activation of the PAC1 receptor.
Steve Bourgault, David Vaudry, Isabelle Ségalas-Milazzo, Laure Guilhaudis, Alain Couvineau, Marc Laburthe

J Med Chem· May 2009

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Aberrant expression of proteinase-activated receptor 4 promotes colon cancer cell proliferation through a persistent signaling that involves Src and ErbB-2 kinase.
Valérie Gratio, Francine Walker, Thérèse Lehy, Marc Laburthe, Dalila Darmoul

Int J Cancer· April 2009

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Biological and structural analysis of truncated analogs of PACAP27.
Steve Bourgault, David Vaudry, Laure Guilhaudis, Emilie Raoult, Alain Couvineau, Marc Laburthe

J Mol Neurosci· November 2008

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Production and purification of large quantities of the functional N-terminal ectodomain of human VPAC1 receptor.
Alain Couvineau, Jean-Claude Robert, Tarik Ramdani, Jean-Jacques Lacapère, Christiane Rouyer-Fessard, Marc Laburthe

J Mol Neurosci· November 2008

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The N-terminal parts of VIP and antagonist PG97-269 physically interact with different regions of the human VPAC1 receptor.
Emilie Ceraudo, Yossan-Var Tan, Pascal Nicole, Alain Couvineau, Marc Laburthe

J Mol Neurosci· November 2008

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PACAP prevents toxicity induced by cisplatin in rat and primate neurons but not in proliferating ovary cells: involvement of the mitochondrial apoptotic pathway.
Nicolas Aubert, David Vaudry, Anthony Falluel-Morel, Arnaud Desfeux, Cécile Fisch, Marc Laburthe

Neurobiol Dis· October 2008

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Class-B GPCR activation: is ligand helix-capping the key?
Jean-Michel Neumann, Alain Couvineau, Samuel Murail, Jean-Jacques Lacapère, Nadège Jamin, Marc Laburthe

Trends Biochem Sci· July 2008

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A hallmark of immunoreceptor, the tyrosine-based inhibitory motif ITIM, is present in the G protein-coupled receptor OX1R for orexins and drives apoptosis: a novel mechanism.
Thierry Voisin, Aadil El Firar, Christiane Rouyer-Fessard, Valérie Gratio, Marc Laburthe

FASEB J· June 2008

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Novel stable PACAP analogs with potent activity towards the PAC1 receptor.
Steve Bourgault, David Vaudry, Béatrice Botia, Alain Couvineau, Marc Laburthe

Peptides· June 2008

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The vasoactive intestinal peptide (VIP) alpha-Helix up to C terminus interacts with the N-terminal ectodomain of the human VIP/Pituitary adenylate cyclase-activating peptide 1 receptor: photoaffinity, molecular modeling, and dynamics.
Emilie Ceraudo, Samuel Murail, Yossan-Var Tan, Jean-Jacques Lacapère, Jean-Michel Neumann, Marc Laburthe

Mol Endocrinol· January 2008

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PAR-2 activation increases human intestinal mucin secretion through EGFR transactivation.
Anne Jarry, Laetitia Dorso, Valérie Gratio, Marie-Elisabeth Forgue-Lafitte, Marc Laburthe

Biochem Biophys Res Commun· December 2007

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Orexins control intestinal glucose transport by distinct neuronal, endocrine, and direct epithelial pathways.
Robert Ducroc, Thierry Voisin, Aadil El Firar, Marc Laburthe

Diabetes· October 2007

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Class II G protein-coupled receptors for VIP and PACAP: structure, models of activation and pharmacology.
Marc Laburthe, Alain Couvineau, Var Tan

Peptides· September 2007

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Involvement of VIP and PACAP in neonatal brain lesions generated by a combined excitotoxic/inflammatory challenge.
Geraldine Favrais, Alain Couvineau, Marc Laburthe, Pierre Gressens, Vincent Lelievre

Peptides· September 2007

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