Publications by authors named "Marc Loriaux"

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Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.
Daniel Bottomly, Nicola Long, Anna Reister Schultz, Stephen E Kurtz, Cristina E Tognon, Marc M Loriaux

Cancer Cell· August 2022

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Aurora A kinase as a target for therapy in rearranged acute lymphoblastic leukemia.
Jessica Leonard, Joelle Sj Wolf, Michelle Degnin, Christopher A Eide, Dorian LaTocha, Marc M Loriaux

Haematologica· November 2021

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Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia.
Adam J Lamble, Yoko Kosaka, Ted Laderas, Allie Maffit, Andy Kaempf, Marc M Loriaux

Proc Natl Acad Sci U S A· June 2020

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Mast cell sarcoma with concurrent mast cell leukaemia.
Lauren M Raymond, Tracy Funk, Rita M Braziel, Guang Fan, Ken Gatter, Marc Loriaux

Br J Haematol· May 2020

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CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells.
David K Edwards, Kevin Watanabe-Smith, Angela Rofelty, Alisa Damnernsawad, Ted Laderas, Marc Loriaux

Blood· February 2019

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Functional genomic landscape of acute myeloid leukaemia.
Jeffrey W Tyner, Cristina E Tognon, Daniel Bottomly, Beth Wilmot, Stephen E Kurtz, Marc M Loriaux

Nature· October 2018

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Synthetic lethality of TNK2 inhibition in PTPN11-mutant leukemia.
Chelsea Jenkins, Samuel B Luty, Julia E Maxson, Christopher A Eide, Melissa L Abel, Marc Loriaux

Sci Signal· July 2018

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Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples.
David K Edwards V, David Tyler Sweeney, Hibery Ho, Christopher A Eide, Angela Rofelty, Marc M Loriaux

Oncotarget· May 2018

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SYK inhibition thwarts the BAFF - B-cell receptor crosstalk and thereby antagonizes Mcl-1 in chronic lymphocytic leukemia.
Cody Paiva, Taylor A Rowland, Bhargava Sreekantham, Claire Godbersen, Scott R Best, Marc M Loriaux

Haematologica· November 2017

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Double autophagy stimulation using chemotherapy and mTOR inhibition combined with hydroxychloroquine for autophagy modulation in patients with relapsed or refractory multiple myeloma.
Emma C Scott, Richard T Maziarz, Stephen E Spurgeon, Eva Medvedova, James Gajewski, Marc Loriaux

Haematologica· July 2017

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CPX-351 exhibits potent and direct ex vivo cytotoxicity against AML blasts with enhanced efficacy for cells harboring the FLT3-ITD mutation.
Max J Gordon, Paul Tardi, Marc M Loriaux, Stephen E Spurgeon, Elie Traer

Leuk Res· February 2017

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Targeting BCL-2 and ABL/LYN in Philadelphia chromosome-positive acute lymphoblastic leukemia.
Jessica T Leonard, Joelle S J Rowley, Christopher A Eide, Elie Traer, Brandon Hayes-Lattin, Marc Loriaux

Sci Transl Med· August 2016

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Alterations in acute myeloid leukaemia bone marrow stromal cell exosome content coincide with gains in tyrosine kinase inhibitor resistance.
Shelton Viola, Elie Traer, Jianya Huan, Noah I Hornick, Jeffrey W Tyner, Marc Loriaux

Br J Haematol· March 2016

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The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I.
Julia E Maxson, Samuel B Luty, Jason D MacManiman, Jason C Paik, Jason Gotlib, Marc M Loriaux

Clin Cancer Res· February 2016

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Small molecule inhibitor screen identifies synergistic activity of the bromodomain inhibitor CPI203 and bortezomib in drug resistant myeloma.
Matthew B Siegel, Selina Qiuying Liu, Monika A Davare, Stephen E Spurgeon, Marc M Loriaux

Oncotarget· August 2015

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Therapeutically Targetable ALK Mutations in Leukemia.
Julia E Maxson, Monika A Davare, Samuel B Luty, Christopher A Eide, Bill H Chang, Marc M Loriaux

Cancer Res· June 2015

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YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway.
Bill H Chang, Kara Johnson, Dorian LaTocha, Joelle S J Rowley, Jade Bryant, Marc Loriaux

J Hematol Oncol· April 2015

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Disruption of IKAROS activity in primitive chronic-phase CML cells mimics myeloid disease progression.
Philip A Beer, David J H F Knapp, Paul H Miller, Nagarajan Kannan, Ivan Sloma, Marc M Loriaux

Blood· January 2015

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BCR-ABL1 promotes leukemia by converting p27 into a cytoplasmic oncoprotein.
Anupriya Agarwal, Ryan J Mackenzie, Arnaud Besson, Sophia Jeng, Alyssa Carey, Marc M Loriaux

Blood· November 2014

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Comparison of methods to identify aberrant expression patterns in individual patients: augmenting our toolkit for precision medicine.
Daniel Bottomly, Peter A Ryabinin, Jeffrey W Tyner, Bill H Chang, Marc M Loriaux

Genome Med· May 2014

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A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor.
Russell T Burke, Sarah Meadows, Marc M Loriaux, Kevin S Currie, Scott A Mitchell

Oncotarget· February 2014

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The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition.
Angela G Fleischman, Julia E Maxson, Samuel B Luty, Anupriya Agarwal, Lacey R Royer, Marc M Loriaux

Blood· November 2013

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A case study of personalized therapy for osteosarcoma.
Lara E Davis, Nicolle E Hofmann, Guangheng Li, Elaine T Huang, Marc M Loriaux

Pediatr Blood Cancer· August 2013

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Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML.
Julia E Maxson, Jason Gotlib, Daniel A Pollyea, Angela G Fleischman, Anupriya Agarwal, Marc M Loriaux

N Engl J Med· May 2013

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Imatinib and Dasatinib Inhibit Hemangiosarcoma and Implicate PDGFR-β and Src in Tumor Growth.
Erin B Dickerson, Kevin Marley, Wade Edris, Jeffrey W Tyner, Vidya Schalk, Marc Loriaux

Transl Oncol· April 2013

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