Publications by authors named "Marc M Loriaux"

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Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.
Daniel Bottomly, Nicola Long, Anna Reister Schultz, Stephen E Kurtz, Cristina E Tognon, Marc M Loriaux

Cancer Cell· August 2022

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Aurora A kinase as a target for therapy in rearranged acute lymphoblastic leukemia.
Jessica Leonard, Joelle Sj Wolf, Michelle Degnin, Christopher A Eide, Dorian LaTocha, Marc M Loriaux

Haematologica· November 2021

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Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia.
Adam J Lamble, Yoko Kosaka, Ted Laderas, Allie Maffit, Andy Kaempf, Marc M Loriaux

Proc Natl Acad Sci U S A· June 2020

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Functional genomic landscape of acute myeloid leukaemia.
Jeffrey W Tyner, Cristina E Tognon, Daniel Bottomly, Beth Wilmot, Stephen E Kurtz, Marc M Loriaux

Nature· October 2018

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Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples.
David K Edwards V, David Tyler Sweeney, Hibery Ho, Christopher A Eide, Angela Rofelty, Marc M Loriaux

Oncotarget· May 2018

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SYK inhibition thwarts the BAFF - B-cell receptor crosstalk and thereby antagonizes Mcl-1 in chronic lymphocytic leukemia.
Cody Paiva, Taylor A Rowland, Bhargava Sreekantham, Claire Godbersen, Scott R Best, Marc M Loriaux

Haematologica· November 2017

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CPX-351 exhibits potent and direct ex vivo cytotoxicity against AML blasts with enhanced efficacy for cells harboring the FLT3-ITD mutation.
Max J Gordon, Paul Tardi, Marc M Loriaux, Stephen E Spurgeon, Elie Traer

Leuk Res· February 2017

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The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I.
Julia E Maxson, Samuel B Luty, Jason D MacManiman, Jason C Paik, Jason Gotlib, Marc M Loriaux

Clin Cancer Res· February 2016

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Small molecule inhibitor screen identifies synergistic activity of the bromodomain inhibitor CPI203 and bortezomib in drug resistant myeloma.
Matthew B Siegel, Selina Qiuying Liu, Monika A Davare, Stephen E Spurgeon, Marc M Loriaux

Oncotarget· August 2015

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Therapeutically Targetable ALK Mutations in Leukemia.
Julia E Maxson, Monika A Davare, Samuel B Luty, Christopher A Eide, Bill H Chang, Marc M Loriaux

Cancer Res· June 2015

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Disruption of IKAROS activity in primitive chronic-phase CML cells mimics myeloid disease progression.
Philip A Beer, David J H F Knapp, Paul H Miller, Nagarajan Kannan, Ivan Sloma, Marc M Loriaux

Blood· January 2015

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BCR-ABL1 promotes leukemia by converting p27 into a cytoplasmic oncoprotein.
Anupriya Agarwal, Ryan J Mackenzie, Arnaud Besson, Sophia Jeng, Alyssa Carey, Marc M Loriaux

Blood· November 2014

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Comparison of methods to identify aberrant expression patterns in individual patients: augmenting our toolkit for precision medicine.
Daniel Bottomly, Peter A Ryabinin, Jeffrey W Tyner, Bill H Chang, Marc M Loriaux

Genome Med· May 2014

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A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor.
Russell T Burke, Sarah Meadows, Marc M Loriaux, Kevin S Currie, Scott A Mitchell

Oncotarget· February 2014

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The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition.
Angela G Fleischman, Julia E Maxson, Samuel B Luty, Anupriya Agarwal, Lacey R Royer, Marc M Loriaux

Blood· November 2013

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A case study of personalized therapy for osteosarcoma.
Lara E Davis, Nicolle E Hofmann, Guangheng Li, Elaine T Huang, Marc M Loriaux

Pediatr Blood Cancer· August 2013

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Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML.
Julia E Maxson, Jason Gotlib, Daniel A Pollyea, Angela G Fleischman, Anupriya Agarwal, Marc M Loriaux

N Engl J Med· May 2013

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The selective SYK inhibitor P505-15 (PRT062607) inhibits B cell signaling and function in vitro and in vivo and augments the activity of fludarabine in chronic lymphocytic leukemia.
Stephen E Spurgeon, Greg Coffey, Luke B Fletcher, Russell Burke, Jeffrey W Tyner, Marc M Loriaux

J Pharmacol Exp Ther· February 2013

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HitWalker: variant prioritization for personalized functional cancer genomics.
Daniel Bottomly, Beth Wilmot, Jeffrey W Tyner, Christopher A Eide, Marc M Loriaux

Bioinformatics· February 2013

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Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening.
Jeffrey W Tyner, Wayne F Yang, Armand Bankhead, Guang Fan, Luke B Fletcher, Marc M Loriaux

Cancer Res· January 2013

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Crosstalk between ROR1 and the Pre-B cell receptor promotes survival of t(1;19) acute lymphoblastic leukemia.
Vincent T Bicocca, Bill H Chang, Behzad Kharabi Masouleh, Markus Muschen, Marc M Loriaux

Cancer Cell· November 2012

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An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma.
Jinu Abraham, Ying Xuan Chua, Jason M Glover, Jeffrey W Tyner, Marc M Loriaux

Biochem Biophys Res Commun· September 2012

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Creation of fibrinogen-enhanced experimental blood clots to evaluate mechanical thrombectomy devices for treatment of acute stroke: an in vitro study.
Zhong Hua Luo, Alex Chung, Gibok Choi, Yih Huie Lin, Barry T Uchida, Marc M Loriaux

J Vasc Interv Radiol· August 2012

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TSLP signaling network revealed by SILAC-based phosphoproteomics.
Jun Zhong, Min-Sik Kim, Raghothama Chaerkady, Xinyan Wu, Tai-Chung Huang, Marc M Loriaux

Mol Cell Proteomics· June 2012

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TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms.
Angela G Fleischman, Karl J Aichberger, Samuel B Luty, Thomas G Bumm, Curtis L Petersen, Marc M Loriaux

Blood· December 2011

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