Publications by authors named "Marc N Offman"

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Comparison of a molecular dynamics model with the X-ray structure of the N370S acid-beta-glucosidase mutant that causes Gaucher disease.
Marc N Offman, Marcin Krol, Burkhard Rost, Israel Silman, Joel L Sussman

Protein Eng Des Sel· October 2011

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A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease.
Alexander Zimprich, Anna Benet-Pagès, Walter Struhal, Elisabeth Graf, Sebastian H Eck, Marc N Offman

Am J Hum Genet· July 2011

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Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity.
Marc N Offman, Marcin Krol, Naina Patel, Shekhar Krishnan, JiZhong Liu

Blood· February 2011

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Molecular basis of reduced glucosylceramidase activity in the most common Gaucher disease mutant, N370S.
Marc N Offman, Marcin Krol, Israel Silman, Joel L Sussman, Anthony H Futerman

J Biol Chem· December 2010

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A dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug L-asparaginase.
Naina Patel, Shekhar Krishnan, Marc N Offman, Marcin Krol, Catherine X Moss

J Clin Invest· July 2009

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Alternating evolutionary pressure in a genetic algorithm facilitates protein model selection.
Marc N Offman, Alexander L Tournier, Paul A Bates

BMC Struct Biol· August 2008

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Developing a move-set for protein model refinement.
Marc N Offman, Paul W Fitzjohn, Paul A Bates

Bioinformatics· August 2006

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No statistical support for correlation between the positions of protein interaction sites and alternatively spliced regions.
Marc N Offman, Ramil N Nurtdinov, Mikhail S Gelfand, Dmitrij Frishman

BMC Bioinformatics· April 2004

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