Publications by authors named "Marc Singleton"

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Evolutionary analyses of intrinsically disordered regions reveal widespread signals of conservation.
Marc D Singleton, Michael B Eisen

PLoS Comput Biol· April 2024

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Leveraging genomic redundancy to improve inference and alignment of orthologous proteins.
Marc Singleton, Michael Eisen

G3 (Bethesda)· December 2023

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Metabolism and pharmacokinetics characterization of metarrestin in multiple species.
Elias C Padilha, Pranav Shah, Amy Q Wang, Marc D Singleton, Emma A Hughes

Cancer Chemother Pharmacol· April 2020

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Phosphocyclocreatine is the dominant form of cyclocreatine in control and creatine transporter deficiency patient fibroblasts.
Kirill Gorshkov, Amy Q Wang, Wei Sun, Ethan Fisher, Marta Frigeni, Marc Singleton

Pharmacol Res Perspect· December 2019

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Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-Kras;Tp53 (KPC) mice, a genetically engineered model of pancreatic cancer.
Tomas Vilimas, Amy Q Wang, Samarjit Patnaik, Emma A Hughes, Marc D Singleton

Cancer Chemother Pharmacol· December 2018

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Preclinical Pharmacological Development of Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection.
Adam Rolt, Derek Le, Zongyi Hu, Amy Q Wang, Pranav Shah, Marc Singleton

J Infect Dis· May 2018

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The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction.
Catherine A Wakeman, Jessica L Moore, Michael J Noto, Yaofang Zhang, Marc D Singleton

Nat Commun· June 2016

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Phevor combines multiple biomedical ontologies for accurate identification of disease-causing alleles in single individuals and small nuclear families.
Marc V Singleton, Stephen L Guthery, Karl V Voelkerding, Karin Chen, Brett Kennedy

Am J Hum Genet· April 2014

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The development of next-generation sequencing assays for the mitochondrial genome and 108 nuclear genes associated with mitochondrial disorders.
Shale Dames, Lan-Szu Chou, Ye Xiao, Tyler Wayman, Jennifer Stocks, Marc Singleton

J Mol Diagn· July 2013

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A probabilistic disease-gene finder for personal genomes.
Mark Yandell, Chad Huff, Hao Hu, Marc Singleton, Barry Moore

Genome Res· September 2011

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Global analysis of disease-related DNA sequence variation in 10 healthy individuals: implications for whole genome-based clinical diagnostics.
Barry Moore, Hao Hu, Marc Singleton, Francisco M De La Vega, Martin G Reese

Genet Med· March 2011

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Validation of DNA-based prognostic testing to predict spinal curve progression in adolescent idiopathic scoliosis.
Kenneth Ward, James W Ogilvie, Marc V Singleton, Rakesh Chettier, Gordon Engler

Spine (Phila Pa 1976)· December 2010

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