Publications by authors named "Marc Winnefeld"

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Primary Keratinocyte Model of Actinic Keratosis Reveals UV-Induced DNA Damage Accumulation and Persistent Interferon Signaling.
Leonardo Elsbroek, Katja Reuschlein, Syrus Karsai, Anna Geueke, Mareike von Petersdorff-Campen, Marc Winnefeld

J Invest Dermatol· December 2025

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Systemic factors in young human serum influence responses of human skin and bone marrow-derived blood cells in a microphysiological co-culture system.
Johanna Ritter, Cassandra Falckenhayn, Minyue Qi, Leonie Gather, Daniel Gutjahr, Marc Winnefeld

Aging (Albany NY)· July 2025

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Identification of dihydromyricetin as a natural DNA methylation inhibitor with rejuvenating activity in human skin.
Cassandra Falckenhayn, Agata Bienkowska, Jörn Söhle, Katrin Wegner, Guenter Raddatz, Marc Winnefeld

Front Aging· March 2024

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Development of an epigenetic clock to predict visual age progression of human skin.
Agata Bienkowska, Günter Raddatz, Jörn Söhle, Boris Kristof, Henry Völzke, Marc Winnefeld

Front Aging· January 2024

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Cohort Profile Update: The Study of Health in Pomerania (SHIP).
Henry Völzke, Janka Schössow, Carsten Oliver Schmidt, Clemens Jürgens, Adrian Richter, Marc Winnefeld

Int J Epidemiol· December 2022

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Macrophages Are Polarized toward an Inflammatory Phenotype by their Aged Microenvironment in the Human Skin.
Leonie Gather, Neetika Nath, Cassandra Falckenhayn, Sergio Oterino-Sogo, Thomas Bosch, Marc Winnefeld

J Invest Dermatol· December 2022

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Single-Cell RNA Profiling of Human Skin Reveals Age-Related Loss of Dermal Sheath Cells and Their Contribution to a Juvenile Phenotype.
Juliane M D Ahlers, Cassandra Falckenhayn, Nicholas Holzscheck, Llorenç Solé-Boldo, Sabrina Schütz, Marc Winnefeld

Front Genet· January 2022

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Modeling transcriptomic age using knowledge-primed artificial neural networks.
Nicholas Holzscheck, Cassandra Falckenhayn, Jörn Söhle, Boris Kristof, Ralf Siegner, Marc Winnefeld

NPJ Aging Mech Dis· June 2021

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Human Adipose-Derived Mesenchymal Stromal/Stem Cell Spheroids Possess High Adipogenic Capacity and Acquire an Adipose Tissue-like Extracellular Matrix Pattern.
Christiane Hoefner, Christian Muhr, Hannes Horder, Miriam Wiesner, Katharina Wittmann, Marc Winnefeld

Tissue Eng Part A· August 2020

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Concomitant DNA methylation and transcriptome signatures define epidermal responses to acute solar UV radiation.
Nicholas Holzscheck, Jörn Söhle, Torsten Schläger, Cassandra Falckenhayn, Elke Grönniger, Marc Winnefeld

Sci Rep· July 2020

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Multi-omics network analysis reveals distinct stages in the human aging progression in epidermal tissue.
Nicholas Holzscheck, Jörn Söhle, Boris Kristof, Elke Grönniger, Stefan Gallinat, Marc Winnefeld

Aging (Albany NY)· June 2020

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Integrated analysis of motif activity and gene expression changes of transcription factors.
Jesper Grud Skat Madsen, Alexander Rauch, Elvira Laila Van Hauwaert, Søren Fisker Schmidt, Marc Winnefeld

Genome Res· February 2018

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Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin.
Manuel Rodríguez-Paredes, Felix Bormann, Günter Raddatz, Julian Gutekunst, Carlota Lucena-Porcel, Marc Winnefeld

Nat Commun· February 2018

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Methacrylated gelatin/hyaluronan-based hydrogels for soft tissue engineering.
Lukas Kessler, Sandra Gehrke, Marc Winnefeld, Birgit Huber, Eva Hoch

J Tissue Eng· December 2017

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Identification of miR-126 as a new regulator of skin ageing.
Jan Fiedler, Elke Grönniger, Angelika Pfanne, Simone Brönneke, Katrin Schmidt, Marc Winnefeld

Exp Dermatol· March 2017

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An integrative metabolomics and transcriptomics study to identify metabolic alterations in aged skin of humans in vivo.
Andreas Kuehne, Janosch Hildebrand, Joern Soehle, Horst Wenck, Lara Terstegen, Marc Winnefeld

BMC Genomics· February 2017

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Integration of Mature Adipocytes to Build-Up a Functional Three-Layered Full-Skin Equivalent.
Birgit Huber, Antonia Link, Kirstin Linke, Sandra A Gehrke, Marc Winnefeld

Tissue Eng Part C Methods· August 2016

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Reduced DNA methylation patterning and transcriptional connectivity define human skin aging.
Felix Bormann, Manuel Rodríguez-Paredes, Sabine Hagemann, Himanshu Manchanda, Boris Kristof, Marc Winnefeld

Aging Cell· June 2016

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Acute Activation of Oxidative Pentose Phosphate Pathway as First-Line Response to Oxidative Stress in Human Skin Cells.
Andreas Kuehne, Hila Emmert, Joern Soehle, Marc Winnefeld, Frank Fischer

Mol Cell· August 2015

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Genome-wide expression analysis of wounded skin reveals novel genes involved in angiogenesis.
Simone Brönneke, Bodo Brückner, Jörn Söhle, Ralf Siegner, Christoph Smuda, Marc Winnefeld

Angiogenesis· July 2015

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Epigenetic regulation of depot-specific gene expression in adipose tissue.
Sandra Gehrke, Bodo Brueckner, Andreas Schepky, Johannes Klein, Alexander Iwen, Marc Winnefeld

PLoS One· September 2014

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Gluteal and abdominal subcutaneous adipose tissue depots as stroma cell source: gluteal cells display increased adipogenic and osteogenic differentiation potentials.
Karl Alexander Iwen, Anna-Christin Priewe, Marc Winnefeld, Christian Rose, Frank Siemers

Exp Dermatol· June 2014

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Aging is associated with highly defined epigenetic changes in the human epidermis.
Günter Raddatz, Sabine Hagemann, Dvir Aran, Jörn Söhle, Pranav P Kulkarni, Marc Winnefeld

Epigenetics Chromatin· October 2013

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Implications of epigenetic mechanisms for vascular development and disease.
Sabine Hagemann, Simone Brönneke, Marc Winnefeld

Epigenomics· October 2012

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