Publications by authors named "Marcel Meima"

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Extreme resistance to thyroid hormone caused by a novel mosaic thyroid hormone receptor beta mutation.
Ferdy S van Geest, Wenjun Liao, Paul G Voorhoeve, Willemijn G Leen, Nitash Zwaveling-Soonawala, Marcel E Meima

Eur Thyroid J· December 2025

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Mechanisms of developmental neurotoxicity mediated by perturbed thyroid hormone homeostasis in the brain: an adverse outcome pathway network.
Nathalie T O M Dierichs, Aldert H Piersma, Robin P Peeters, W Edward Visser, Marcel E Meima

Crit Rev Toxicol· May 2025

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Mapping variants in thyroid hormone transporter MCT8 to disease severity by genomic, phenotypic, functional, structural and deep learning integration.
Stefan Groeneweg, Ferdy S van Geest, Mariano Martín, Mafalda Dias, Jonathan Frazer, Marcel E Meima

Nat Commun· March 2025

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Two novel in vitro assays to screen chemicals for their capacity to inhibit thyroid hormone transmembrane transporter proteins OATP1C1 and OAT4.
Fabian Wagenaars, Peter Cenijn, Zhongli Chen, Marcel Meima, Martin Scholze

Arch Toxicol· September 2024

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3,3',5-Triiodothyroacetic Acid Transporters.
Zhongli Chen, Sena Yildiz, Boyka Markova, Linda J de Rooij, Selmar Leeuwenburgh, Marcel E Meima

Thyroid· August 2024

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Resistance to Thyroid Hormone Beta Due to Mutation in a Patient Misdiagnosed With TSH-Secreting Pituitary Adenoma.
Wenjun Liao, Nipawan Waisayanand, Kanda Fanhchaksai, W Edward Visser, Marcel E Meima

JCEM Case Rep· August 2024

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Identification of Iodotyrosines as Novel Substrates for the Thyroid Hormone Transporter MCT8.
Stefan Groeneweg, Chantal Zevenbergen, Elaine C Lima de Souza, Ferdy S van Geest, Barbara Kloeckener-Gruissem, Marcel E Meima

Thyroid· July 2024

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Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.
Rosalie B T M Sterenborg, Inga Steinbrenner, Yong Li, Melissa N Bujnis, Tatsuhiko Naito, Marcel E Meima

Nat Commun· January 2024

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Decreased hepatic thyroid hormone signaling in systemic and liver-specific but not brain-specific accelerated aging due to DNA repair deficiency in mice.
Sander Barnhoorn, Marcel E Meima, Robin P Peeters, Veerle M Darras, Selmar Leeuwenburgh

Eur Thyroid J· December 2023

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Novel (sulfated) thyroid hormone transporters in the solute carrier 22 family.
Zhongli Chen, Robin P Peeters, Wesley Flach, Linda J de Rooij, Sena Yildiz, Marcel E Meima

Eur Thyroid J· August 2023

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Asymmetrical Transport of Thyroxine Across Human Term Placenta.
Zhongli Chen, Robin P Peeters, Selmar Leeuwenburgh, Michelle Broekhuizen, Rugina I Neuman, Marcel E Meima

Thyroid· May 2023

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Thyroid Hormone Transporters in Pregnancy and Fetal Development.
Zhongli Chen, Marcel E Meima, Robin P Peeters, W Edward Visser

Int J Mol Sci· December 2022

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Thyroid Hormone Transporters in a Human Placental Cell Model.
Zhongli Chen, A S Elise van der Sman, Stefan Groeneweg, Linda Johanna de Rooij, W Edward Visser, Marcel E Meima

Thyroid· September 2022

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Binding Characteristics of Thyroid Hormone Distributor Proteins to Thyroid Hormone Metabolites.
Rutchanna M S Jongejan, Marcel E Meima, W Edward Visser, Tim I M Korevaar, Sjoerd A A van den Berg

Thyroid· August 2022

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The Effects of Common Genetic Variation in 96 Genes Involved in Thyroid Hormone Regulation on TSH and FT4 Concentrations.
Rosalie B T M Sterenborg, Tessel E Galesloot, Alexander Teumer, Romana T Netea-Maier, Doug Speed, Marcel E Meima

J Clin Endocrinol Metab· May 2022

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Functional Characterization of the Novel and Specific Thyroid Hormone Transporter SLC17A4.
Stefan Groeneweg, Ferdy S van Geest, Zhongli Chen, Stefania Farina, Ramona E A van Heerebeek, Marcel E Meima

Thyroid· March 2022

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Change in Thyroid Hormone Metabolite Concentrations Across Different Thyroid States.
Rutchanna M S Jongejan, Evert F S van Velsen, Marcel E Meima, Theo Klein, Sjoerd A A van den Berg

Thyroid· February 2022

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The pyriproxyfen metabolite, 4'-OH-PPF, disrupts thyroid hormone signaling in neural stem cells, modifying neurodevelopmental genes affected by ZIKA virus infection.
Pieter Vancamp, Petra Spirhanzlova, Anthony Sébillot, Lucile Butruille, Jean-David Gothié, Marcel Meima

Environ Pollut· September 2021

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Clinical and Functional Consequences of C-Terminal Variants in MCT8: A Case Series.
Ferdy S van Geest, Marcel E Meima, Kyra E Stuurman, Nicole I Wolf, Marjo S van der Knaap

J Clin Endocrinol Metab· January 2021

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Insights Into the Mechanism of MCT8 Oligomerization.
Stefan Groeneweg, Amanda van den Berge, Elaine C Lima de Souza, Marcel E Meima, Robin P Peeters

J Endocr Soc· August 2020

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A Mass Spectrometry-Based Panel of Nine Thyroid Hormone Metabolites in Human Serum.
Rutchanna M S Jongejan, Theo Klein, Marcel E Meima, W Edward Visser, Ramona E A van Heerebeek

Clin Chem· April 2020

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Removing Critical Gaps in Chemical Test Methods by Developing New Assays for the Identification of Thyroid Hormone System-Disrupting Chemicals-The ATHENA Project.
Andreas Kortenkamp, Marta Axelstad, Asma H Baig, Åke Bergman, Carl-Gustaf Bornehag, Marcel E Meima

Int J Mol Sci· April 2020

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The Functional Impairment of Thyroid Hormone Receptor Alpha 1 Isoform Mutants Is Mainly Dictated by Reduced Ligand Sensitivity.
Karn Wejaphikul, Anja L M van Gucht, Stefan Groeneweg, W Edward Visser, Theo J Visser, Marcel E Meima

Thyroid· December 2019

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Characterization of Human, Mouse, and Zebrafish MCT8 Orthologues.
Stefan Groeneweg, Simone Kersseboom, Amanda van den Berge, Anna Dolcetta-Capuzzo, Ferdy S van Geest, Marcel E Meima

Thyroid· October 2019

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Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis.

JAMA· August 2019

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