Publications by authors named "Marcel Spulak"

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Evaluation of pharmacokinetics, pharmacodynamics, and toxicity of potential quinazoline bronchodilators derived from vasicinone.
Marcel Špulák, Dominik Nelic, Alena Randáková, Klára Konečná, Ondřej Janďourek

J Pharmacol Exp Ther· August 2025

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2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR).
Zuzana Rania Brožová, Jan Dušek, Norbert Palša, Jana Maixnerová, Rajamanikkam Kamaraj

Eur J Med Chem· November 2023

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Sustainable ionic liquids-based molecular platforms for designing acetylcholinesterase reactivators.
Illia V Kapitanov, Marcel Špulák, Milan Pour, Ondřej Soukup, Jan Marek

Chem Biol Interact· November 2023

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Derivatives of montanine-type alkaloids and their implication for the treatment of Alzheimer's disease: Synthesis, biological activity and in silico study.
Negar Maafi, Filip Pidaný, Jana Maříková, Jan Korábečný, Daniela Hulcová

Bioorg Med Chem Lett· November 2021

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Stability study of α-bromophenylacetic acid: Does it represent an appropriate model analyte for chiral separations?
Pavel Jáč, Zuzana Bubáková, David Moreno-González, Gabriela Kováčová, Marcel Špulák

Electrophoresis· October 2020

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Correction to 2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists.
Tomas Smutny, Alice Nova, Marcela Drechslerová, Alejandro Carazo, Lucie Hyrsova

J Med Chem· December 2016

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2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists.
Tomas Smutny, Alice Nova, Marcela Drechslerová, Alejandro Carazo, Lucie Hyrsova

J Med Chem· May 2016

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Novel bronchodilatory quinazolines and quinoxalines: synthesis and biological evaluation.
Marcel Špulák, Jana Pourová, Marie Vopršálová, Jiří Mikušek, Jiří Kuneš

Eur J Med Chem· March 2014

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Investigation of the metabolism of monepantel in ovine hepatocytes by UHPLC/MS/MS.
Lucie Stuchlíková, Robert Jirásko, Ivan Vokřál, Jiří Lamka, Marcel Spulák

Anal Bioanal Chem· February 2013

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Synthesis and biological activity of desmethoxy analogues of coruscanone A.
Lucie Tichotová, Eliška Matoušová, Marcel Spulák, Jiří Kuneš, Ivan Votruba

Bioorg Med Chem Lett· October 2011

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3,5-disubstituted pyranone analogues of highly antifungally active furanones: conversion of biological effect from antifungal to cytostatic.
Radan Schiller, Lucie Tichotová, Jan Pavlík, Vladimír Buchta, Bohuslav Melichar

Bioorg Med Chem Lett· December 2010

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Antifungal 3,5-disubstituted furanones: From 5-acyloxymethyl to 5-alkylidene derivatives.
Petr Senel, Lucie Tichotová, Ivan Votruba, Vladimír Buchta, Marcel Spulák

Bioorg Med Chem· March 2010

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Direct C-H arylation and alkenylation of 1-substituted tetrazoles: phosphine as stabilizing factor.
Marcel Spulák, Richard Lubojacký, Petr Senel, Jirí Kunes, Milan Pour

J Org Chem· January 2010

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A short entry to alpha-substituted gamma-alkylidene pentenolides. Synthesis and preliminary biological evaluation of novel gelastatin analogues.
Jan Pavlík, Ivan Snajdr, Jirí Kunes, Marcel Spulák, Milan Pour

J Org Chem· January 2009

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In vitro activities of 3-(halogenated phenyl)-5-acyloxymethyl- 2,5-dihydrofuran-2-ones against common and emerging yeasts and molds.
Vladimír Buchta, Milan Pour, Petra Kubanová, Luis Silva, Ivan Votruba

Antimicrob Agents Chemother· March 2004

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Synthesis and structure-antifungal activity relationships of 3-aryl-5-alkyl-2,5-dihydrofuran-2-ones and their carbanalogues: further refinement of tentative pharmacophore group.
Milan Pour, Marcel Spulák, Vojtech Balsánek, Jirí Kunes, Petra Kubanová

Bioorg Med Chem· July 2003

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