Publications by authors named "Marcel Wuthrich"

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Endoglucanase 2 (Eng2), a shared immunodominant antigen in dimorphic fungi that elicits immunity during infection.
Uju J Okaa, Cleison Ledesma Taira, Lucas Dos Santos Dias, Hannah Dobson, Gregory C Kujoth

J Clin Invest· November 2025

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Brain-infiltrating CD4 T cells drive inflammatory microglia proliferation during cryptococcal meningitis in mice.
Sofia Hain, Man Shun Fu, Lucy Wigg, Lorna George, David Lecky, Marcel Wuthrich

Nat Commun· October 2025

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Endoglucanase-2 (Eng2), a conserved immunodominant antigen in dimorphic fungi that elicits immunity and resistance during infection.
Uju Joy Okaa, Cleison Ledesma Taira, Lucas Dos Santos Dias, Hannah Dobson, Gregory Kujoth

bioRxiv· June 2025

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Vaccination with O-linked Mannans Protects against Systemic Candidiasis through Innate Lymphocyte Populations.
Cleison Ledesma Taira, Lucas Dos Santos Dias, Sarah Lichtenberger, Alexander J Whitehead, Brenda Kischkel

J Immunol· September 2024

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The C-Type Lectin Receptor Dectin-2 Is a Receptor for Aspergillus fumigatus Galactomannan.
Jennifer L Reedy, Arianne J Crossen, Paige E Negoro, Hannah Brown Harding, Rebecca A Ward

mBio· February 2023

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Distinctive populations of CD4T cells associated with vaccine efficacy.
Therese Woodring, Colin N Dewey, Lucas Dos Santos Dias, Xin He, Hannah E Dobson

iScience· September 2022

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SLAMF1 Is Dispensable for Vaccine-Induced T Cell Development but Required for Resistance to Fungal Infection.
Elaine M Kohn, Lucas Dos Santos Dias, Hannah E Dobson, Xin He, Huafeng Wang

J Immunol· March 2022

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Variation in Host Resistance to Blastomyces dermatitidis: Potential Use of Genetic Reference Panels and Advances in Immunophenotyping of Diverse Mouse Strains.
Elaine M Kohn, Cleison Taira, Hanah Dobson, Lucas Dos Santos Dias, Uju Okaa

mBio· February 2022

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Combination Adjuvants Enhance Recombinant Protein Vaccine Protection against Fungal Infection.
Marcel Wüthrich, Hannah E Dobson, Cleison Ledesma Taira, Uju Joy Okaa, Lucas Dos Santos Dias

mBio· August 2021

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Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity.
Lucas Dos Santos Dias, Hannah E Dobson, Brock Kingstad Bakke, Gregory C Kujoth, Junfeng Huang

PLoS Pathog· March 2021

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CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Infection.
Althea Campuzano, Hao Zhang, Gary R Ostroff, Lucas Dos Santos Dias, Marcel Wüthrich

J Immunol· June 2020

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Early immune response against Fonsecaea pedrosoi requires Dectin-2-mediated Th17 activity, whereas Th1 response, aided by Treg cells, is crucial for fungal clearance in later stage of experimental chromoblastomycosis.
Isaque Medeiros Siqueira, Marcel Wüthrich, Mengyi Li, Huafeng Wang, Lucas de Oliveira Las-Casas

PLoS Negl Trop Dis· June 2020

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Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance.
Hannah E Dobson, Lucas Dos Santos Dias, Elaine M Kohn, Scott Fites, Darin L Wiesner

Mucosal Immunol· May 2020

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Radiologists and nuclear medicine physicians are looking forward to a cross-curricular training.
Soung Yung Kim, Theodoros Xydias, Alan A Peters, Michael P Brönnimann, Marcel Wüthrich

Eur Radiol· September 2019

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Infectious particle identity determines dissemination and disease outcome for the inhaled human fungal pathogen Cryptococcus.
Naomi M Walsh, Michael R Botts, Andrew J McDermott, Sébastien C Ortiz, Marcel Wüthrich

PLoS Pathog· June 2019

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Virally-vectored vaccine candidates against white-nose syndrome induce anti-fungal immune response in little brown bats (Myotis lucifugus).
Tonie E Rocke, Brock Kingstad-Bakke, Marcel Wüthrich, Ben Stading, Rachel C Abbott

Sci Rep· May 2019

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Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.
Nydiaris Hernández-Santos, Darin L Wiesner, J Scott Fites, Andrew J McDermott, Thomas Warner

Cell Host Microbe· April 2019

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Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.
Nydiaris Hernández-Santos, Darin L Wiesner, J Scott Fites, Andrew J McDermott, Thomas Warner

Cell Host Microbe· April 2018

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CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen Blastomyces dermatitidis.
Gregory C Kujoth, Thomas D Sullivan, Richard Merkhofer, Taek-Jin Lee, Huafeng Wang

mBio· April 2018

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Dectin-2 Is a C-Type Lectin Receptor that Recognizes Pneumocystis and Participates in Innate Immune Responses.
Theodore J Kottom, Deanne M Hebrink, Paige E Jenson, Paige L Marsolek, Marcel Wüthrich

Am J Respir Cell Mol Biol· February 2018

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O-Mannosylation of Proteins Enables Yeast Survival at Mammalian Body Temperatures.
Andrew L Garfoot, Kristie D Goughenour, Marcel Wüthrich, Murugesan V S Rajaram, Larry S Schlesinger

mBio· January 2018

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Ligation of Dectin-2 with a novel microbial ligand promotes adjuvant activity for vaccination.
Huafeng Wang, Taek-Jin Lee, Scott J Fites, Richard Merkhofer, Robert Zarnowski

PLoS Pathog· August 2017

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Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense.
Philipp Wiemann, Adi Perevitsky, Fang Yun Lim, Yana Shadkchan, Benjamin P Knox

Cell Rep· June 2017

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Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense.
Philipp Wiemann, Adi Perevitsky, Fang Yun Lim, Yana Shadkchan, Benjamin P Knox

Cell Rep· May 2017

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Antifungal Tc17 cells are durable and stable, persisting as long-lasting vaccine memory without plasticity towards IFNγ cells.
Som Gowda Nanjappa, Andrew J McDermott, J Scott Fites, Kevin Galles, Marcel Wüthrich

PLoS Pathog· May 2017

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